CAS: 316-81-4; N,N-Dimethyl-10-(3-(4-Methylpiperazin-1-yl)Propyl)-10H-Phenothiazine-2-Sulfonamide

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CAS号5510-56-5 4-((2-氨基苯基)硫代)-... | CAS号53106-13-1 N-[2-[4-(dimeth... | CAS号1217018-61-5 N-(3-chloroprop... | CAS号1090-78-4 N,N-二甲基吩噻嗪-2-磺酰胺

合成工艺路线路线简述

    📜4-(2-Acetylamino-Phenylsulfanyl)-N,N-Dimethyl-3-Nitro-Benzenesulfonamide置于sodium Hydroxide体系中,用 乙醇,丙酮 作为反应溶剂,化学反应生成 硫丙拉嗪
    参考文献:Synthesis And Comparison Of Activity Of 2-And 3-Dimethylsulfamidophenothiazine Derivatives
    标题:Synthesis And Comparison Of Activity Of 2-And 3-Dimethylsulfamidophenothiazine Derivatives
    摘要:
    DOI:10.1007/bf00771334

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    专利信息


    专利号:US-2008214827-A1
    优先权日:2004-02-03
    标 题:Synthesis of Cyanoimino-Benzoimidazoles
    发明人:GOEHRING R RICHARD; WHITEHEAD JOHN; SHAO BIN
    权利人:EURO CELTIQUE SA
    摘要:Disclosed in certain embodiments is a process for synthesizing a compound of formula (V) and salts thereof.

    专利号:US-7300639-B2
    优先权日:2002-12-03
    标 题:Process for removing metals from liquids
    发明人:LIU WANSHENG
    权利人:BRISTOL MYERS SQUIBB CO
    摘要:A process is provided for removing one or more metals from liquids. Also provided is a process for the synthesis of aP2 inhibiting compounds having the formula (I) n nwherein R 1 , R 2 , R 3 , R 4 , HET, and X-Z are as described herein, which process comprising the step of removing one or more metals from a solution of the compound of formula I or an intermediate or precursor thereof. The processes for removing metal comprise the step of contacting the liquid with a solid extractant comprising a metal-binding functionality.

    专利号:EP-3103803-B1
    优先权日:2008-10-27
    标 题 :Intermediates for the synthesis of mtor kinase inhibitors

    专利号:CA-2555219-A1
    优先权日:2004-02-03
    标 题 :Synthesis of cyanoimino-benzoimidazoles

    专利号:US-11759496-B2
    优先权日:2016-05-10
    标题:Compounds and pharmaceutical use thereof in the treatment of cancer
    发明人:SUSIN SANTOS A; KAROYAN PHILIPPE; MERLE-BERAL HÉLÈNE
    权利人:KAROYAN PHILIPPE
    摘要:The present invention relates to a compound or a pharmaceutical salt thereof comprising a hexapeptide sequence of formula (I), its method of synthesis and its use in anticancer therapy. The invention also relates to a pharmaceutical composition for use in the treatment of cancer comprising at least one soluble peptide according to the invention or at least one acid nucleic according to the invention or at least one expression vector according to the invention, or at least one host cell according to the invention and a pharmaceutically acceptable carrier.

    专利号:US-2023271983-A1
    优先权日:2020-07-29
    标题 :Functionalized isonitriles and products, preparation and uses thereof
    发明人:SOTELO PÉREZ EDDY; AZUAJE GUERRERO JHONNY ALBERTO; MAJELLARO MARIA
    权利人:UNIV SANTIAGO COMPOSTELA
    摘要:The present invention relates to functionalized isonitrile compounds, formed by means of multicomponent environmentally friendly reactions, suitable for coupling to functional molecules such as biomolecules, APIs, chromophore and fluorophore molecules. The invention also relates to conjugates between said isonitrile compounds and functional molecules, which are useful in the synthesis of pharmaceutic drugs or tools, fluorescent molecules and labels, polymeric smart materials. The invention furthermore provides a kit for the in-vitro preparation of the functionalized isontrile compounds and conjugates. The invention also contemplates the medical use of said compounds and conjugates.

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    主要参考文献


    1: Marois G, Henrotte JG, Elie C, Franck G. [Changes in plasma prolactin and magnesium in male rats treated with thioproperazine and/or bromocriptine]. Ann Endocrinol (Paris). 1985;46(6):399-405. French. French. French. French. French. French. French. French. French. Spanish. French. German.

    合成参考文献


    摘要:Developments in Neuroscience, 7(45), 1980
    摘要:S72 | NTUPHTW | Pharmaceutically Active Substances from National Taiwan University | DOI:10.5281/zenodo.3955664
    参考文献:10.1007/bf01271201
    摘要:Griffon N, Pilon C, Sautel F, Schwartz JC, Sokoloff P. Antipsychotics with inverse agonist activity at the dopamine D3 receptor. J Neural Transm (Vienna). 1996;103(10):1163–75. doi: 10.1007/bf01271201.
    摘要:REBEILLARD M, VIDAL B, VIDAL G, VALERY B. [Thioproperazine in psychiatric practice. (Apropos of 133 cases)]. Gaz Med Fr. 1961 Jul 25;68():1853–9.
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