CAS: 29106-49-8; (2R,2'R,3R,3'R,4R)-2,2'-Bis(3,4-Dihydroxyphenyl)-[4,8'-Bichromane]-3,3',5,5',7,7'-Hexaol

上下游产品

CAS号223387-28-8 5,7,3',4'-tetra... | CAS号442626-19-9 3',4',5,7-tetra... | CAS号87292-49-7 tetrabeuzyl-(-)... | CAS号20728-73-8 5,7,3',4'-四-O-苄基儿茶素 | CAS号87292-54-4 (2R)-2-[3,4-bis... | CAS号154-23-4 儿茶精； 儿茶素； (2R,3... | CAS号256236-25-6 (2R,3R)-2-[3,4-... | CAS号490-46-0 表儿茶素(EC) | CAS号79907-44-1 原花青素B2-3,3'-二-O... | CAS号490-46-0 表儿茶素(EC) | CAS号154-23-4 儿茶精； 儿茶素； (2R,3... | CAS号41743-41-3 原花青素A2

[(2R,3R,4R)-2-(3,4-二羟基苯基)-4-[(2R,3R)-2-(3,4-二羟基苯基)-5,7-二羟基-3-(3,4,5-三羟基苯甲酰基)氧基-色满-8-基]-5,7-二羟基-色满-3-基]3,4,5-三羟基苯甲酸酯置于单宁酶体系中,用 水 用作溶剂,化学反应 1.0H,反应生成原花青素 B2
参考文献:Stilbene Glycoside Gallates And Proanthocyanidins From Polygonum Multiflorum
标题:Stilbene Glycoside Gallates And Proanthocyanidins From Polygonum Multiflorum
摘要:Two New Stilbene Glycoside Gallates And Proanthocyanidins Were Isolated From P. Multiflorum. The Stilbenes Were 2"-And 3"-O-Monogalloyl Esters Of 2,3,5,4''-Tetrahydroxystilbene 2-O-.Beta.-D-Glucopyranoside.
Doi:10.1016/s0031-9422(00)95282-8

专利信息

专利号:US-9133176-B2
优先权日:2002-02-15
标题:Isolation, purification and synthesis of procyanidin B2 and uses thereof
发明人：CASTILLO GERARDO; NGUYEN BETH; CHOI PAULA; LARSEN LESLEY; LORIMER STEPHEN; SNOW ALAN
权利人:CASTILLO GERARDO; NGUYEN BETH; CHOI PAULA; LARSEN LESLEY; LORIMER STEPHEN; SNOW ALAN; PROTEOTECH INC
摘要:Methods for the synthesis, isolation, and purification of procyanidin B2 are disclosed. The synthetic methods utilize epicatechin as a starting material and produce procyanidin B2 in high yields. The isolation methods extract procyanidin B2 from a sample of bark powder from plant matter of the genus Uncaria . The isolated and/or synthesized procyanidin B2 is used to treat amyloid disease, such as Alzheimer's disease and Parkinson's disease as well as improve cognitive performance and increase learning and memory in Alzheimer's patients. Pharmaceutical compositions containing the synthesized and/or isolated procyanidin B2 are also disclosed.

专利号:US-7126014-B2
优先权日:2000-09-05
标题 :Synthesis of epecatechin-4α, 8-epicatechin and -catechin dimers and derivatives thereof
发明人：KOZIKOWSKI ALAN P; ROMANCZYK JR LEO J; TUECKMANTEL WERNER
权利人:MARS INC
摘要:Oligomeric procyanidins containing 4α-linked epicatechin units are rare in nature and have hitherto not been accessible through stereoselective synthesis. Provided herein is the preparation of the prototypical dimer, epicatechin-4α,8-epicatechin, by reaction of the protected 4-ketones with aryllithium reagents derived by halogen/metal exchange from the aryl bromides. Removal of the 4-hydroxyl group from the resulting tertiary benzylic alcohols is effected by tri-n-butyltin hydride and trifluoroacetic acid in a completely stereoselective manner, resulting in hydride delivery exclusively from the β face.

专利号:EP-1921076-A1
优先权日:2002-10-11
标题:systhesis of procyanidin B2
发明人：CASTILLO GERARDO M; NGUYEN BETH P; CHOI PAULA Y; LARSEN LESLEY; LORIMER STEPHEN D; SNOW ALAN D
权利人:PROTEOTECH INC
摘要:Methods for the synthesis of procyanidin B2 are disclosed. The synthetic methods utilize epicatechin as a starting material and produce procyanidin BZ in high yields.

专利号:US-2007036742-A1
优先权日:2005-08-09
标题 :Methods and compositions for modulating hair growth or regrowth
发明人：ROUFS JAMES B; DUVEL LANE A; FAST DAVID J; GLYNN KELLY M
权利人:ACCESS BUSINESS GROUP INT LLC
摘要:The present invention relates to compositions and methods for modulating hair growth or regrowth. The compositions of the present invention comprise extracts of one or more of the following: Boswellia serrata, Undaria pinnatifida, green tea (e.g., Camellia sinensis ), shiso, Pureraria mirifica, luteolin (e.g. Perilla ocymoides leaf extract), astilbin, vitamin E, amentoflavone, tetrahydropiperine, licochalcone, astaxanthin, red clover, Brassica juncea, unfermented green rooibos, enzyme CoQ10, salvia, ximenynic acid, hops oleoresin, apple, soy, saw palmetto, or ellagic extract, or any derivative thereof. In particular, the compositions and methods of the present invention can be used to stimulate or increase hair growth and/or prevent or slow the loss of hair by having one or more of the following functions: (a) inhibiting synthesis of DHT; (b) inhibiting proteasomal activity; (c) inhibiting IL-1 activity; (d) increasing vascularization; (e) increasing expression of vascular endothelial growth factor; (f) increasing expression of keratinocyte growth factor; (g) inhibiting inflammation; or (h) acting as an antibacterial.

专利号:US-2003100775-A1
优先权日:2000-09-05
标 题 :Synthesis of 4alpha-arylepicatechins

专利号:US-2007197804-A1
优先权日:2000-09-05
标题:Synthesis of 4alpha-arylepicatechins