CAS: 2561-17-3; 3-Fluorophenylacetylene

上下游产品

CAS号40230-96-4 1-[(三甲基硅基)乙炔基]-3-氟苯 | CAS号115665-64-0 (Z)-1-(2-bromov... | CAS号402-63-1 1-(3-氟苯基)乙醇 | CAS号350-51-6 间氟苯乙烯 | CAS号17318-03-5 3-氟苯基溴化镁 | CAS号1073-06-9 间溴氟苯 | CAS号462-06-6 氟苯 | CAS号455-38-9 间氟苯甲酸 | CAS号455-36-7 间氟苯乙酮 | CAS号350-51-6 间氟苯乙烯 | CAS号446065-20-9 4-(3-氟苯基)-2-噻唑胺 | CAS号29778-28-7 1-氟-3-(2-苯基乙炔)苯 | CAS号52059-53-7 2-(3-氟苯基)乙醇 | CAS号75321-89-0 2-(3-氟苯基)乙醛 | CAS号1246566-50-6 | CAS号99-09-2 间硝基苯胺 | CAS号67562-20-3 异丁基硼酸频那醇酯

📜3-氟苯乙烯置于dipotassium Peroxodisulfate,2,2,6,6-四甲基哌啶氧化物,Potassium Tert-Butylate体系中,用 四氢呋喃,甲苯 用作溶剂,化学反应 25.0H,反应生成1-乙炔基-3-氟苯
参考文献:Mof 触发的亚纳米 Ag02 团簇和 Fe3+ 单原子的合成:异质化导致高效和协同的一锅催化反应
标题:Mof 触发的亚纳米 Ag02 团簇和 Fe3+ 单原子的合成:异质化导致高效和协同的一锅催化反应
摘要:金属有机骨架 (Mof) 通道内定义明确的 Fe 3+孤立单金属原子和 Ag 2亚纳米金属簇的组合首次通过单晶 X 射线衍射进行了报道和表征.所得杂化材料,分子式为[ag 0 2 (Ag 0 ) 1.34 Fe Iii 0.66 ]@na I 2 {ni Ii 4 [cu Ii 2 (Me 3 Mpba) 2 ] 3 }.63H 2 O ( Fe 3+银0 2 @mof),能够在一锅中催化苯乙烯前所未有地直接转化为苯乙炔.特别是,Fe 3+ Ag 0 2 @mof--可以很容易地以克规模获得--对苯乙烯与苯砜的无 Tempo 氧化交叉偶联表现出优异的催化活性,以产生乙烯基砜,产率高达 >99 %,最终原位转化为相应的苯乙炔产物.这里展示的结果构成了一个典型的例子,说明在明确定义的固体催化剂中合成不同的金属物种,结合溶液中有机反应的真正金属催化剂的物种形成,允许设计一个新的具有挑战性的反应.
Doi:10.1021/jacs.3C02155

专利信息

专利号:US-12291547-B2
优先权日:2019-06-14
标题 :Synthesis of 3-azido-3-deoxy-D-galactopyranose
发明人：GIGUÈRE DENIS; ST-GELAIS JACOB; DENAVIT VINCENT
权利人:UNIV LAVAL
摘要:The present application provides a synthetic method for production of 3-azido-3-deoxy-D-galactopyranose. Also provided are methods of using the 3-azido-3-deoxy-D-galactopyranose in the manufacture of galactoside galectin antagonists, such as TD139 (GB0139), GB1107, GB2064, and GB1211.

专利号:US-10799522-B2
优先权日:2015-07-27
标 题 :Compositions and methods relating to galectin detection
发明人：GELOVANI JURI G; TURKMAN NASHAAT; POPOV VADIM; BONOMI ROBIN; SHAVRIN ALEKSANDR; ALTHER PHILIP; BORISOV ANDREI
权利人:UNIV WAYNE STATE
摘要:Compositions and methods for detection and assessment of galectins are provided by the present invention, including labeled compositions, pharmaceutical composition including a labeled composition for galectin detection and a pharmaceutically acceptable carrier, method of aiding in diagnosis and/or treatment of a condition characterized by upregulation of one or more galectins in a subject in need thereof and precursor compositions for synthesis of chemical compositions, including but not limited to labeled compositions for detection and assessment of galectins.

专利号:US-8772301-B2
优先权日:2009-12-18
标题 :Compounds for treating disorders mediated by metabotropic glutamate receptor 5, and methods of use thereof
发明人：HARDY LARRY WENDELL; HEFFERNAN MICHELE L R; WU FRANK XINHE; SPEAR KERRY L; SARASWAT LAKSHMI D
权利人:HARDY LARRY WENDELL; HEFFERNAN MICHELE L R; WU FRANK XINHE; SPEAR KERRY L; SARASWAT LAKSHMI D; SUNOVION PHARMACEUTICALS INC
摘要:Provided herein are compounds and methods of synthesis thereof. The compounds set forth herein are useful for the treatment, prevention, and/or management of various disorders, such as neurological disorders, neurodegenerative disorders, neuropsychiatric disorders, disorders of cognition, learning or memory, gastrointestinal disorders, lower urinary tract disorder, and cancer. Compounds set forth herein modulate the activity of metabotropic glutamate receptor 5 (mGluR5) in the central nervous system or the periphery. Pharmaceutical formulations containing the compounds and their methods of use are also provided herein.

专利号:US-2022251132-A1
优先权日:2019-06-24
标 题 :Large scale process of 3,3'-dideoxy-3,3'-bis-[4-(3-fluorophenyl)-1h-1,2,3-triazol-1-yl]-1,1'-sulfanediyl-di-beta-d-galactopyranoside
发明人：ZETTERBERG FREDRIK; TYRELL ANDREW; NILSSON ULF; BERGH ANDERS; CUMMINS JONATHAN; WEYMOUTH-WILSON ALEXANDER; CLARKSON ROBERT
权利人:GALECTO BIOTECH AB
摘要:The present invention relates to a process for preparing a compound of formula (I) n n n n n n n n n n wherein said process is suitable for large scale synthesis.

专利号:US-2022251129-A1
优先权日:2019-06-14
标题:Synthesis of 3-azido-3-deoxy-d-galactopyranose

专利号:WO-2020248068-A1
优先权日:2019-06-14
标 题 :Synthesis of 3-azido-3-deoxy-d-galactopyranose