CAS: 2441-97-6; 3-Chlorocyclohex-1-Ene

该化合物是一种有机化合物,其特征是环己环,在三点处有一个氯替代体; 色色的黄色液体,其独特的气味是氯化碳氢化合物的典型; 氯原子的存在使分子极分化,影响其再活性和溶性. 3-氯环己烷已知会参与各种化学反应,包括核生殖替代和电除虫添加,原因是环己环未饱和; 其沸点和密度受到氯原子的影响,这也影响其间分子相互作用; 该化合物在有机合成中使用,并可作为其他化学品生产的中间体; 在处理三氯环己烷时,有必要采取安全防范措施,因为通过皮肤吸入或吸收会有害,而且可能造成环境危害; 应采用适当的储存和处置方法,以减少其使用的风险.

结构式图片

相似化合物

1228943-80-3 1192-88-7 5709-98-8

物理性质

MSDS等安全信息

欧盟法规

ECHA物质C&L通报

上下游产品

CAS号822-67-3 2-环己烯-1-醇 | CAS号286-20-4 环氧环己烷 | CAS号124-63-0 甲基磺酰氯 | CAS号1521-51-3 3-溴环己烯 | CAS号110-83-8 环己烯 | CAS号13698-16-3 乙基 二氯氨基甲酸酯 | CAS号1165952-91-9 cyclohexa-1,3-diene | CAS号55045-25-5 phenyltrichloro... | CAS号40969-10-6 biphenyl-2,2'-d... | CAS号822-67-3 2-环己烯-1-醇 | CAS号15129-33-6 3-cyclohex-2-en... | CAS号519-23-3 椭圆玫瑰树碱溶液 | CAS号930-68-7 环己烯酮 | CAS号591-48-0 3-甲基-1-环己烯 | CAS号542-18-7 氯代环己烷 | CAS号1541-20-4 3,3'-Bi[cyclohexene] | CAS号1145-98-8 二苯基四甲基二硅烷 | CAS号110-83-8 环己烯

合成工艺路线路线简述

  • 合成目标产物 3-Chlorocyclohexene 主要起始原料 2-Cyclohexen-1-Ol
  • 1713-33-3 = 2441-97-6 + 822-86-6
    反应条件:1.1 Reagents: Trichloroisocyanuric Acid,Triphenylphosphine Solvents: Acetonitrile; 5 - 10 Min,Neutralized,Reflux
    标题:Trihaloisocyanuric Acid/triphenylphosphine: An Efficient System For Regioselective Conversion Of Epoxides Into Vicinal Halohydrins And Vicinal Dihalides Under Mild Conditions
    作者:De Andrade,Vitor S. C.; Et Al
    参考文献:Synthesis 日期:2016 卷标:48(9) 页码:1381-1388]

    = 2441-97-6 + 822-86-6
    反应条件:1.1 Reagents: (Oc-6-21)-Tetrachloro[methylenebis(1,3-Dihydro-3-Tetradecyl-1H-Imidazol-1-Yl-2(3... Catalysts: Tetrabutylammonium Chloride Solvents: Chloroform-D; 2 H,25 °C
    标题:Bis-N-Heterocyclic Carbene Palladium(Iv) Tetrachloride Complexes: Synthesis,Reactivity,And Mechanisms Of Direct Chlorinations And Oxidations Of Organic Substrates
    作者:Mccall,A. Scott; Et Al
    参考文献:Journal Of The American Chemical Society 日期:2011 卷标:133(6) 页码:1832-1848]

    = 2441-97-6 + 822-86-6
    反应条件:1.1 Reagents: Palladium(1+),Trichloro[methylenebis(3-Tetradecyl-1H-Imidazol-1-Yl-2(3H)-Yliden... Solvents: Chloroform-D; 25 °C
    标题:Pyridine-Assisted Chlorinations And Oxidations By Palladium(Iv)
    作者:Mccall,A. Scott; Et Al
    参考文献:Organometallics 日期:2012 卷标:31(9) 页码:3527-3538]

    = 2441-97-6 + 822-86-6
    反应条件:1.1 Reagents: Tetrabutylammonium Chloride,(Oc-6-23)-(Nitrato-Ko)Oxo[5,10,15,20-Tetrakis(2,3,4,5,6-Pentafluorophenyl)-21H,2... Solvents: Dichloromethane; 2 Min,-80 °C; -80 °C -> Rt
    标题:Oxidation Of Chloride And Subsequent Chlorination Of Organic Compounds By Oxoiron(Iv) Porphyrin π-Cation Radicals
    作者:Cong,Zhiqi; Et Al
    参考文献:Angewandte Chemie 日期:2011 卷标:50(42) 页码:9935-9939
📜Cyclohexen-1-Ol置于草酰氯,Chlorotriphenylphosphonium Chloride体系中,用 氯仿 用作溶剂,化学反应 7.0H,以103 Mg的收率获得3-氯环己烯
参考文献:催化磷(v)介导的亲核取代反应:催化appel反应的发展.
标题:催化磷(v)介导的亲核取代反应:催化appel反应的发展.
摘要:已经开发了催化磷(v)介导的醇的氯化和溴化反应.新反应构成了经典appel卤化反应的催化形式.在这些新反应中,草酰氯用作消耗化学计量试剂,以产生卤化catalytic盐,这些卤化salts盐由催化氧化膦.因此,氧化膦已经从化学计量的废物转化为催化剂,并且已经验证了基于催化磷的醇的活化和亲核取代的新概念.本研究集中于对氧化膦催化的氯化反应的范围和局限性的全面探索,以及类似溴化反应的发展.进一步的机理研究,包括对催化循环中间体的密度泛函理论计算,与以卤代和烷氧基phosph盐为中间体的催化循环是一致的.
Doi:10.1021/jo201085R

海关参考信息

专利信息


专利号:WO-2015008097-A1
优先权日:2013-07-19
标 题:Asymmetric synthesis of chiral compounds
发明人：FLETCHER STEPHEN PATRICK; PORTELA MIREIA SIDERA; YOU HENGZHI; RIDEAU EMELINE
权利人:ISIS INNOVATION; FLETCHER STEPHEN PATRICK; PORTELA MIREIA SIDERA; YOU HENGZHI; RIDEAU EMELINE
摘要:The present invention provides processes for the production of chiral compounds in a stereoisomeric excess, the processes comprising: (i) contacting a first compound comprising an alkene or alkyne bond with a hydrometallating agent, wherein the first compound and the hydrometallating agent are contacted under conditions such that the first compound is hydrometallated by said hydrometallating agent; and (ii) contacting the hydrometallated first compound with a second compound comprising an allylic group, wherein the hydrometallated first compound and the second compound are contacted under conditions such that they undergo an asymmetric allylic alkylation reaction in which a carbon atom of the hydrometallated first compound binds to a carbon atom of said allylic group, forming a stereoisomeric excess of a compound having a chiral centre in an allylic position, said chiral centre being located at the carbon atom bound by said first compound, wherein said asymmetric allylic alkylation reaction is performed in the presence of a metal catalyst comprising a chiral ligand. In particular, the present invention provides processes for the production of a stereoisomeric excess of a compound of the formula (IA), (IB), (IA') or (IB') as defined herein.

专利号:US-11999688-B2
优先权日:2018-06-20
标题 :Method for producing dicarboxylic acid
发明人：HUANG SHENGJUN; ZHANG DAZHI
权利人:DALIAN INST CHEM & PHYSICS CAS
摘要:A method for producing dicarboxylic acid. The method includes: subjecting a raw material system including a cyclic olefin and a lower monocarboxylic acid to an addition reaction in the presence of an addition reaction catalyst to generate an intermediate product system including cyclic carboxylic acid ester; and subjecting the intermediate product system including cyclic carboxylic acid ester to a ring-opening and oxidation reaction in the presence of an oxidant and an oxidation catalyst to generate a corresponding dicarboxylic acid product. The addition reaction in the dicarboxylic acid synthesis route achieves a high single-pass conversion rate, and the selectivity of the corresponding cyclic carboxylic acid ester is high. The addition-oxidation synthesis route achieves faster reaction rates for both the addition reaction and oxidation reaction, and high yield of corresponding dicarboxylic acid product. The addition-oxidation based synthesis route is suitable for continuous, stable and large-scale production of corresponding dicarboxylic acid product.

专利号:JP-S6219548-A
优先权日:1985-07-19
标题 :Synthesis method of aldehyde

其他信息查阅

供应商参考报价(招募中)

品牌试剂参考报价(招募中)

实用工具

⚠️全国化工行业净网倡议书
📋制造商识别码
📖 海关编码查询
📝MSDS生成器

📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

合成参考文献


摘要:Hafeman, N. J.; Sardini, S. R., Jr.; Bhat, V.; Stoltz, B. M., Science of Synthesis, (2022) , 295.
📝 需求与反馈
尽可能描述清楚需求与问题信息
×

通知