CAS: 223251-16-9; (4-(2-(Azepan-1-yl)Ethoxy)Phenyl)Methanol

上下游产品

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4-(2-Oxo-2-Hexamethyleneimino-Ethoxy)-Benzaldehyde置于红铝体系中,用 甲苯 用作溶剂,化学反应生成(4-(2-(氮杂环庚烷-1-基)乙氧基)苯基)甲醇
参考文献:Processes For The Preparation Of Aminoethoxybenzyl Alcohols
标题:Processes For The Preparation Of Aminoethoxybenzyl Alcohols
摘要:本发明提供了制备公式i中的氨乙氧基苄醇的过程和中间体,该化合物在制备药用化合物中有用.

专利信息

专利号:US-6268504-B1
优先权日:1997-10-15
标题 :Aryloxy-alkyl-dialkylamines
发明人：RAVEENDRANATH PANOLIL; ZELDIS JOSEPH; VID GALINA; POTOSKI JOHN R; REN JIANXIN; IERA SILVIO
权利人:AMERICAN HOME PROD
摘要:The present invention provides compounds useful in the synthesis of biologically active compounds, and processes for their production, the compounds having the formula:wherein: R1 and R2 are, independently, selected from H; C1-C12 alkyl or C1-C6 perfluorinated alkyl; X represents a leaving group; A is O or S; m is an integer from 1 to 3, preferably 2; R3, R4, R5, and R6 are independently selected from H, halogen, -NO2, alkyl, alkoxy, C1-C6 perfluorinated alkyl, OH or the C1-C4 esters or alkyl ethers thereof, -CN, -O-R1, -O-Ar, -S-R1, -S-Ar, -SO-R1, -SO-Ar, -SO2-R1, -SO2-Ar, -CO-R1, -CO-Ar, -CO2-R1, or -CO2-Ar; and Y is selected from a) the moiety:wherein R7 and R8 are independently selected from the group of H, C1-C6 alkyl, or phenyl; or b) an optionally substituted five-, six- or seven-membered saturated, unsaturated or partially unsaturated heterocycle or bicyclic heterocycle containing up to two heteroatoms selected from the group consisting of -O-, -NH-, -N(C1C4 alkyl)-, -N=, and -S(O)n-.