CAS: 20555-88-8; 6-(Hydroxyamino)Pyrimidin-2(1H)-One

相似化合物

71-30-7 20555-88-8 71-30-7

上下游产品

Cytosine 4-methylsulfanylpyrimidin-2(1H)-one 4-hydroxyimino-5,6-dihydro-6-hydroxyaminopyrimidin-2(1H)-one Cytosine

📜胞嘧啶置于硫酸羟胺,Sodium Methylate体系中,用 乙醇,水 用作溶剂,以93.7%的收率获得6-羟基l氨基尿嘧啶
参考文献:N4-羟基胞苷的制备方法
标题:N4-羟基胞苷的制备方法
摘要:本发明揭示了一种具有预防和治疗包括新冠(Covid‑19)在内的多种病毒感染作用的n4‑羟基胞苷的制备方法,其制备步骤包括:以胞嘧啶和四乙酰核糖为起始原料,经羟胺化,缩合和水解反应制得n4‑羟基胞苷.该制备方法原料易得,工艺简洁,经济环保,适合工业化生产.

专利信息

专利号:WO-2020141143-A1
优先权日:2019-01-03
标 题:One pot synthesis of sets of oligonucleotides

专利号:US-12056264-B2
优先权日:2016-09-21
标题:Nucleic acid based data storage
发明人：PECK BILL JAMES
权利人:TWIST BIOSCIENCE CORP
摘要:Provided herein are compositions, devices, systems and methods for the generation and use of biomolecule-based information for storage. Additionally, devices described herein for de novo synthesis of nucleic acids encoding information related to the original source information may be rigid or flexible material. Further described herein are highly efficient methods for long term data storage with 100% accuracy in the retention of information. Also provided herein are methods and systems for efficient transfer of preselected polynucleotides from a storage structure for reading stored information.

专利号:EP-3906317-A1
优先权日:2019-01-03
标 题:One pot synthesis of sets of oligonucleotides

专利号:EP-1179598-B1
优先权日:1999-05-13
标题 :Process for producing nucleoside compound
发明人：NIKUMARU SEIYA; NAKAMURA TAKESHI
权利人:MITSUI CHEMICALS INC
摘要:In preparation of a nucleoside compound by reacting a pentose-1-phosphate and a nucleic acid base or its analogue in the presence of enzyme activity of nucleoside phosphorylase, a metal salt capable of forming a water-insoluble salt with phosphoric acid may be added to a reaction system to eliminate phosphoric acid, a byproduct, from the reaction system so that the equilibrium reaction can be shifted toward a direction for nucleoside synthesis, leading to an improved yield of the desired nucleoside compound.

专利号:US-2021332078-A1
优先权日:2015-05-11
标 题:Compositions and methods for nucleic acid amplification
发明人：WU CHENG-HSIEN
权利人:TWIST BIOSCIENCE CORP
摘要:The present disclosure provides compositions, methods and systems for the efficient removal of a non-target nucleic acid sequence from a double stranded nucleic acid amplification product. A non-target nucleic acid sequence may be a primer sequence incorporated into the double stranded nucleic acid molecule during a nucleic acid synthesis or amplification reaction. The non-target nucleic acid sequence may include a nucleobases that are not canonical DNA nucleobases, such as uracil, that can be selectively removed as part of the non-target sequence removal process.

专利号:CN-114540320-B
优先权日:2022-03-28
标题 :Cytidine hydroxylase, its genes, uses and synthesis method of the new coronavirus oral drug Molnupiravir