📜N-[2-(二甲氨基)-2-氧乙基]-氨基甲酸-1,1-二甲基乙酯置于三氟乙酸体系中,用 二氯甲烷 用作溶剂,化学反应生成N,N-二甲基甘氨酰胺 参考文献:Highly Selective And Sensitive Detection Of Biogenic Defense Phytohormone Salicylic Acid In Living Cells And Plants Using A Novel And Viable Rhodamine-Functionalized Fluorescent Probe 标题:Highly Selective And Sensitive Detection Of Biogenic Defense Phytohormone Salicylic Acid In Living Cells And Plants Using A Novel And Viable Rhodamine-Functionalized Fluorescent Probe 摘要:Detecting Plant-Derived Signal Molecules Using Fluorescent Probes Is A Key Topic And A Huge Challenge For Scientists. Salicylic Acid (Sa),A Vital Plant-Derived Defense Hormone,Can Activate Global Transcriptional Reprogramming To Systemically Express A Network Of Prominent Pathogenesis-Related Proteins Against Invasive Microorganisms. This Strategy Is Called Systemic Acquired Resistance (Sar). Therefore,Monitoring The Dynamic Fluctuations Of Sa In Subcellular Microenvironments Can Advance Our Understanding Of Different Physiological And Pathological Functions During The Sa-Induced Sar Mechanism,Thus Benefiting The Discovery And Development Of Novel Immune Activators That Contribute To Crop Protection. Here,Detection Of Signaling Molecule Sa In Plant Callus Tissues Was First Reported And Conducted By A Simple Non-Fluorescent Rhodamine-Tagged Architecture Bearing A Flexible 2-Amino-N,N-Dimethylacetamide Pattern. This Study Can Markedly Advance And Promote The Usage Of Fluorescent Sa Probes For Distinguishing Sa In The Plant Kingdom. Doi:10.1021/acs.Jafc.9B06771
专利号:US-2021395200-A1 优先权日:2018-11-16 标 题:Synthetic processes for the production of 1-((3s,4r)-4-(2,6-difluoro-4-methoxyphenyl)-2-oxopyrrolidin-3-yl)-3-phenylurea 发明人:ORTIZ ADRIAN; BOROVIKA ALINA; KOLOTUCHIN SERGEI; LUZUNG MICHAEL R; NYE JEFFREY A; TAN YICHEN; ZARETSKY SERGE; ZHU JASON J; EASTGATE MARTIN D 权利人:BRISTOL MYERS SQUIBB CO 摘要:Highly efficient processes are provided for preparing key intermediates in the synthesis of compounds (I). The process are broadly applicable and can provide selected components having a variety of substituents. Some intermediates are claimed.
专利号:US-6465656-B2 优先权日:1999-10-21 标题 :Synthesis of 1,3,5-trisubstituted pyrazoles 发明人:ZHOU JIACHENG; OH LYNETTE MAY; CONFALONE PASQUALE N; LI HUI-YIN; MA PHILIP 权利人:BRISTOL MYERS SQUIBB PHARMA CO 摘要:A novel process for making 1,3,5-trisubstituted pyrazoles of the type shown below from appropriate phenyl hydrazines is described. n These compounds are useful as factor Xa inhibitors.
专利号:US-6329527-B1 优先权日:1999-10-21 标题 :Synthesis of 1,3,5-trisubstituted pyrazoles
专利号:US-2002055641-A1 优先权日:1999-10-21 标 题 :Synthesis of 1,3,5-trisubstituted pyrazoles
专利号:RU-2010796-C1 优先权日:1986-10-13 标 题:Method of synthesis of 3-propenylcepheme derivatives or theirs pharmaceutically acceptable salts
专利号:EP-0062161-A1 优先权日:1981-03-04 标 题 :Synthesis of amides using carbamic-acid salts