CAS: 155934-55-7; (4R,5R)-2,2-Dimethyl-5-Vinyl-1,3-Dioxolane-4-Carbaldehyde

英文名称(4R,5R)-2,2-Dimethyl-5-Vinyl-1,3-Dioxolane-4-Carbaldehyde
中文名称替格瑞洛杂质128
IUPAC名称(4R,5R)-2,2-dimethyl-5-vinyl-1,3-dioxolane-4-carbaldehyde
其它别名D-Erythro-Pent-4-Enose, 4,5-Dideoxy-2,3-O-(1-Methylethylidene)- (9Ci); D-Erythro-Pent-4-Enose, 4,5-Dideoxy-2,3-O-(1-Methylethylidene)-; (4R,5R)-2,2-Dimethyl-5-Vinyl-[1,3]Dioxolane-4-Carbaldehyde
CAS编号155934-55-7
分子式:C8H12O3分子量:156.18
产品CID: 775372
产品分类分析化学 → 标准品 → 药典标准品和杂质标准品

相似结构搜索
InChIKey: AMXAGLAPRRVGDY-RQJHMYQMSA-N
InChI=1S/C8H12O3/c1-4-6-7(5-9)11-8(2,3)10-6/h4-7H,1H2,2-3H3/t6-,7+/m1/s1
计算化学: 氢键受体数3.0氢键供体数*可旋转键数2.0

MSDS等安全信息

上下游产品

methyl 5-deoxy-5-iodo-2,3-isopropylidene-β-D-ribofuranoside (3aS,4S,6aR)-4-(iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole (4S,5R)-2,2-dimethyl-4-hydroxymethyl-5-vinyl-1,3-dioxolane 2,3-O-isopropylidene-D-ribofuranose (4S,5R)-2,2-dimethyl-4-hydroxymethyl-5-vinyl-1,3-dioxolane N-(4S,5R)-benzyl-((2,2-dimethyl-5-vinyl-[1,3]dioxolan-4-yl)methylene)amine 1,2,7,8-tetradeoxy-3-benzoyl-5,6-O-isopropylidene-D-allo-°Cta-1,7-dienitol

合成工艺路线路线简述

📜2,3-O-Isopropylidene-D-Ribose置于咪唑,碘,三苯基膦体系中,用四氢呋喃用作溶剂,化学反应生成替格瑞洛杂质128
参考文献:Thioimidate N-Oxides: From Nature To Synthetic Pathways
标题:Thioimidate N-Oxides: From Nature To Synthetic Pathways
摘要:受天然存在的脱硫脂肪草的意外反应性的启发,已经设计了在简单或碳水化合物模板上的硫亚胺n-氧化物(tio)的合成方法.无论是通过卤环化还是米特松布条件,起始的硫醇肟会环化以高效生成相应的tio.
Doi:10.1055/s-0029-1219382

海关参考信息

2901210000-乙烯
2901220000-丙烯
2905122000-异丙醇
2905310000-1,2-乙二醇
💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
详情请参考：📖 海关编码查询和海关进出口税则

其他信息查阅

供应商参考报价(招募中)

品牌试剂参考报价(招募中)

实用工具

📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

主要参考文献

参考标题:Synthesis Of Gabosine A And N From Ribose By The Use Of Ring-Closing Metathesis
作者:Rune Nygaard Monrad,Mette Fanefjord,Flemming Gundorph Hansen,N. Michael E. Jensen,Robert Madsen |发布日期:2009.1
摘要:Six-Membered Gabosine Skeleton By Ring-Closing Olefin Metathesis. Subsequent Protective Group Manipulations And Oxidation Gives Rise To Gabosine N In A Total Of 8 Steps From Ribose While The Synthesis Of Gabosine A Employs An Additional Step For Inverting A Secondary Hydroxy Group. (© Wiley-Vch Verlag Gmbh & Co. Kgaa, 69451 Weinheim, Germany, 2009)