专利号:US-2010173100-A1 优先权日:2006-01-16 标题 :Method for the synthesis of product molecules 发明人:WEISS HORST; GERBER GUSTAV; NUERNBERGER PATRICK HENNING; WOLPERT DANIEL STEPHAN 权利人:BASF AG 摘要:The invention relates to a method for the synthesis of product molecules, wherein ultrashort laser pulses shaped with the aid of a pulse shaper are generated and a gas which contains educt molecules is fed onto a surface, on which the educt molecules are at least partially adsorbed, the shaped ultrashort laser pulses being directed onto the surface in order to control a reaction process for synthesis of the product molecules from educts adsorbed on the surface.
专利号:US-9512162-B2 优先权日:2012-07-31 标题 :Synthesis of deuterated ribo nucleosides, N-protected phosphoramidites and oligonucleotides 发明人:SRIVASTAVA SURESH C; YASKO AMY 权利人:ASED LLC 摘要:The present invention is directed towards the synthesis of high purity deuterated sugars, deuterated phosphoramidites, deuterated nucleobases, deuterated nucleosides, deuterated oligonucleotides, and deuterated RNA's of defined sequences which can exhibit biochemically useful and biologically valuable properties, thus having potential for therapeutic uses.
专利号:US-9493773-B2 优先权日:2012-07-31 标题:Synthesis of deuterated ribo nucleosides, N-protected phosphoramidites, and oligonucleotides 发明人:SRIVASTAVA SURESH C; YASKO AMY 权利人:ASED LLC 摘要:The present invention is directed towards the synthesis of high purity deuterated sugars, deuterated phosphoramidites, deuterated nucleobases, deuterated nucleosides, deuterated oligonucleotides, and deuterated RNA's of defined sequences which can exhibit biochemically useful and biologically valuable properties, thus having potential for therapeutic uses.
专利号:US-9365607-B1 优先权日:2012-07-31 标题 :Synthesis of deuterated ribo nucleosides, N-protected phosphoramidites, and oligonucleotides 发明人:SRIVASTAVA SURESH C; YASKO AMY 权利人:ASED LLC 摘要:The present invention is directed towards the synthesis of high purity deuterated sugars, deuterated phosphoramidites, deuterated nucleobases, deuterated nucleosides, deuterated oligonucleotides, and deuterated RNA's of defined sequences which can exhibit biochemically useful and biologically valuable properties, thus having potential for therapeutic uses.
专利号:WO-2012088402-A1 优先权日:2010-12-22 标题 :Synthesis of conolidine and discovery of a potent non-opioid analgesic for pain 发明人:BOHN LAURA M; MICALIZIO GLENN C 权利人:SCRIPPS RESEARCH INST; BOHN LAURA M; MICALIZIO GLENN C 摘要:The first de novo synthetic pathway to the exceptionally rare C5-nor stemmadenine natural product, conolidine, and the first asymmetric synthesis of any member of this natural product class arc described. C5-nor stemmadenine compositions are also described. These compounds, for example,(+/- )-,(+)- and (-)-conolidine are potent and efficacious non-opioid analgesics in tonic and persistent pain.
专利号:US-7632975-B2 优先权日:2004-12-22 标 题:Process for the synthesis of arylfluorenes and analogs thereof 发明人:HEIDENHAIN SOPHIE 权利人:CDT OXFORD LTD 摘要:A process is provided for the synthesis of a compound of formula (I): n nwherein:n M=0 or 1; N and p are 0 or 1 to 4; X is a single bond, O, S or NH; And R 1 -R 4 are as defined in claim 1.