CAS: 13983-20-5; Deuterium Hydride

该化合物是一种化学化合物,由分子式HD所代表,由1个原子和1个氢原子组成.这是一种稳定的氢同位素,除单质子外,还有1个中子(H),使其约比普通氢重一倍.氢离子化物是一种无色,无味的室温气体,与普通氢具有类似的化学特性,尽管由于存在非盈利性,它具有独特的物理特性.它与普通氢相比,它具有更高的沸点和密度.氢离子还被用于各种科学应用,包括核磁共振光谱学和化学与生物研究中的痕量.它独特的同位素构成使得能够研究反应机制和分子动态.此外,它还在脱酸化合物的生产中发挥着作用,这些化合物在制药和先进材料中都很宝贵.

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    专利信息


    专利号:US-2010173100-A1
    优先权日:2006-01-16
    标题 :Method for the synthesis of product molecules
    发明人:WEISS HORST; GERBER GUSTAV; NUERNBERGER PATRICK HENNING; WOLPERT DANIEL STEPHAN
    权利人:BASF AG
    摘要:The invention relates to a method for the synthesis of product molecules, wherein ultrashort laser pulses shaped with the aid of a pulse shaper are generated and a gas which contains educt molecules is fed onto a surface, on which the educt molecules are at least partially adsorbed, the shaped ultrashort laser pulses being directed onto the surface in order to control a reaction process for synthesis of the product molecules from educts adsorbed on the surface.

    专利号:US-9512162-B2
    优先权日:2012-07-31
    标题 :Synthesis of deuterated ribo nucleosides, N-protected phosphoramidites and oligonucleotides
    发明人:SRIVASTAVA SURESH C; YASKO AMY
    权利人:ASED LLC
    摘要:The present invention is directed towards the synthesis of high purity deuterated sugars, deuterated phosphoramidites, deuterated nucleobases, deuterated nucleosides, deuterated oligonucleotides, and deuterated RNA's of defined sequences which can exhibit biochemically useful and biologically valuable properties, thus having potential for therapeutic uses.

    专利号:US-9493773-B2
    优先权日:2012-07-31
    标题:Synthesis of deuterated ribo nucleosides, N-protected phosphoramidites, and oligonucleotides
    发明人:SRIVASTAVA SURESH C; YASKO AMY
    权利人:ASED LLC
    摘要:The present invention is directed towards the synthesis of high purity deuterated sugars, deuterated phosphoramidites, deuterated nucleobases, deuterated nucleosides, deuterated oligonucleotides, and deuterated RNA's of defined sequences which can exhibit biochemically useful and biologically valuable properties, thus having potential for therapeutic uses.

    专利号:US-9365607-B1
    优先权日:2012-07-31
    标题 :Synthesis of deuterated ribo nucleosides, N-protected phosphoramidites, and oligonucleotides
    发明人:SRIVASTAVA SURESH C; YASKO AMY
    权利人:ASED LLC
    摘要:The present invention is directed towards the synthesis of high purity deuterated sugars, deuterated phosphoramidites, deuterated nucleobases, deuterated nucleosides, deuterated oligonucleotides, and deuterated RNA's of defined sequences which can exhibit biochemically useful and biologically valuable properties, thus having potential for therapeutic uses.

    专利号:WO-2012088402-A1
    优先权日:2010-12-22
    标题 :Synthesis of conolidine and discovery of a potent non-opioid analgesic for pain
    发明人:BOHN LAURA M; MICALIZIO GLENN C
    权利人:SCRIPPS RESEARCH INST; BOHN LAURA M; MICALIZIO GLENN C
    摘要:The first de novo synthetic pathway to the exceptionally rare C5-nor stemmadenine natural product, conolidine, and the first asymmetric synthesis of any member of this natural product class arc described. C5-nor stemmadenine compositions are also described. These compounds, for example,(+/- )-,(+)- and (-)-conolidine are potent and efficacious non-opioid analgesics in tonic and persistent pain.

    专利号:US-7632975-B2
    优先权日:2004-12-22
    标 题:Process for the synthesis of arylfluorenes and analogs thereof
    发明人:HEIDENHAIN SOPHIE
    权利人:CDT OXFORD LTD
    摘要:A process is provided for the synthesis of a compound of formula (I): n nwherein:n M=0 or 1; N and p are 0 or 1 to 4; X is a single bond, O, S or NH; And R 1 -R 4 are as defined in claim 1.

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    合成参考文献


    摘要:Tian, T.; Li, Z., Science of Synthesis Knowledge Updates, (2020) 2, 410.
    摘要:Claver, C.; Peñafiel, I.; Urrutigoïty, M.; Kalck, P., Science of Synthesis: Catalytic Reduction in Organic Synthesis, (2018) 2, 304.
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