CAS: 121080-96-4; D-Homocitrulline

该化合物是属于氨基酸和衍生物类的化学化合物,其特点是结构中存在一个顺流合金组(OH),有助于极地溶剂中的溶解性;该组经常因其潜在的生物活动,包括其在代谢途径中的作用及其与各种生物系统的互动而进行研究;氨基基组(-NH2)及其结构中的碳oxylic酸组(-COOH)表明,它可以参与各种生物化学反应,使其与生物化学和药理等领域有关;此外,H-D-Homot-OH可能展示特定的立体化学学,从而影响其与酶或受体的再活动及互动;其应用可能延伸到药物开发,营养和理解代谢失调的研究;然而,为了充分阐明其在科学和医学方面的特性和潜在用途,必须进行详细研究.

结构式图片

相似化合物

1190-49-4 201485-38-3 201485-17-8

上下游产品

urea L-Lysine hydr°Chloride L-Hom°Citrullinhydantoinpipecolinic acid α-Benzyloxycarbonyl-L-hom°CitrullinNα-Benzyloxycarbonyl-L-hom°Citrullin α-Benzyloxycarbonyl-L-hom°Citrullin-p-nitrophenylesterNα-Benzyloxycarbonyl-L-hom°Citrullin-p-nitrophenylester

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    📜4-[(4R)-2,5-Dioxoimidazolidin-4-Yl]Butylurea 以70%的收率获得
    参考文献:Drauz,Karlheinz;Kottenhahn,Matthias;Makryaleas,Kyriakos;Klenk,Herbert+,Angew. Chem.,103,(1991) N,C. 704-706
    标题:Drauz,Karlheinz;Kottenhahn,Matthias;Makryaleas,Kyriakos;Klenk,Herbert+,Angew. Chem.,103,(1991) N,C. 704-706

    海关参考信息

    专利信息


    专利号:US-9574189-B2
    优先权日:2005-12-01
    标题:Enzymatic encoding methods for efficient synthesis of large libraries
    发明人:FRANCH THOMAS; LUNDORF MIKKEL DYBRO; JACOBSEN SØREN NYBOE; OLSEN EVA KAMPMANN; ANDERSEN ANNE LEE; HOLTMANN ANETTE; HANSEN ANDERS HOLM; SØRENSEN ANDERS MALLING; GOLDBECH ANNE; DE LEON DAEN; KALDOR DITTE KIEVSMOSE; SLØK FRANK ABILDGAARD; HUSEMOEN GITTE NYSTRUP; DOLBERG JOHANNES; Jensen Kim Birkebæ; PEDERSEN LENE; NØRREGAARD-MADSEN MADS; GODSKESEN MICHAEL ANDERS; GLAD SANNE SCHRØDER; NEVE SØREN; THISTED THOMAS; KRONBORG TINE TITILOLA AKINLEMINU; SAMS CHRISTIAN KLARNER; FELDING JAKOB; FRESKGÃ…RD PER-OLA; GOULIAEV ALEX HAAHR; PEDERSEN HENRIK
    权利人:FRANCH THOMAS; LUNDORF MIKKEL DYBRO; JACOBSEN SØREN NYBOE; OLSEN EVA KAMPMANN; ANDERSEN ANNE LEE; HOLTMANN ANETTE; HANSEN ANDERS HOLM; SØRENSEN ANDERS MALLING; GOLDBECH ANNE; DE LEON DAEN; KALDOR DITTE KIEVSMOSE; SLØK FRANK ABILDGAARD; HUSEMOEN GITTE NYSTRUP; DOLBERG JOHANNES; Jensen Kim Birkebæ; PEDERSEN LENE; NØRREGAARD-MADSEN MADS; GODSKESEN MICHAEL ANDERS; GLAD SANNE SCHRØDER; NEVE SØREN; THISTED THOMAS; KRONBORG TINE TITILOLA AKINLEMINU; SAMS CHRISTIAN KLARNER; FELDING JAKOB; FRESKGÃ…RD PER-OLA; GOULIAEV ALEX HAAHR; PEDERSEN HENRIK; NUEVOLUTION AS
    摘要:Disclosed is a method for obtaining a bifunctional complex comprising a molecule linked to a single stranded identifier oligonucleotide, wherein a nascent bifunctional complex comprising a chemical reaction site and a priming site for enzymatic addition of a tag is a) reacted at the chemical reaction site with one or more reactants, and b) reacted enzymatically at the priming site with one or more tag(s) identifying the reactant(s).

    专利号:US-2009264300-A1
    优先权日:2005-12-01
    标题 :Enzymatic encoding methods for efficient synthesis of large libraries

    专利号:US-2020216836-A1
    优先权日:2005-12-01
    标题 :Enzymatic encoding methods for efficient synthesis of large libraries

    专利号:US-5434138-A
    优先权日:1990-08-04
    标 题:Gonadoliberin antagonists
    发明人:KOENIG WOLFGANG; SANDOW JUERGEN; KOLAR CENEK
    权利人:HOECHST AG
    摘要:Peptides of the formula in which X is alkanoyl, A is optionally substituted D-Nal(2), D-Phe or D-Trp, B is optionally substituted D-Phe, C is D-Pal(3) or optionally substituted D-Phe or D-Trp, and D is Tyr or His, E is D-Ser (R1), F is Leu, Trp or Phe, G is L-Ser(R1), H is Gly-NH2, D-Ala-NH2 or Azagly-NH2 and R1 is a glycosyl radical. These peptides have an inhibitory effect on the formation of the gonadotropins lutropin and follitropin and thus also on the synthesis of testo-sterone and estrogen. A process for the preparation of these peptides is described.

    专利号:US-2019330618-A1
    优先权日:2005-12-01
    标题 :Enzymatic encoding methods for efficient synthesis of large libraries

    专利号:US-2017247688-A1
    优先权日:2005-12-01
    标题:Enzymatic encoding methods for efficient synthesis of large libraries

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    ✅ COA系统入驻 | 共享模式

    主要参考文献

    参考标题:Enzymatic Encoding Methods For Efficient Synthesis Of Large Libraries
    摘要:Disclosed Is A Method For Obtaining A Bifunctional Complex Comprising A Molecule Linked To A Single Stranded Identifier Oligonucleotide, Wherein A Nascent Bifunctional Complex Comprising A Chemical Reaction Site And A Priming Site For Enzymatic Addition Of A Tag Is A) Reacted At The Chemical Reaction Site With One Or More Reactants, And B) Reacted Enzymatically At The Priming Site With One Or More Tag(S) Identifying The Reactant(S).

    合成参考文献


    参考文献:10.1007/bf01811962
    摘要:Yano T, Korkut E, Pinski J, Szepeshazi K, Milovanovic S, Groot K, Clarke R, Comaru-Schally AM, Schally AV. Inhibition of growth of MCF-7 MIII human breast carcinoma in nude mice by treatment with agonists or antagonists of LH-RH. Breast Cancer Research and Treatment. 1992 Feb;21(1):35–45. doi: 10.1007/bf01811962.
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