专利号:CN-113087691-B 优先权日:2021-03-26 标题:A method for the synthesis of chiral aryl tertiary alcohols and benzopyrans based on a kinetic resolution strategy
专利号:CN-113372184-A 优先权日:2021-03-26 标 题 :A method for the synthesis of C–N-axis chiral phenanthridines based on a chirality transfer strategy
专利号:CN-113087691-A 优先权日:2021-03-26 标 题:A method for the synthesis of chiral aryl tertiary alcohols and benzopyrans based on kinetic resolution strategy
专利号:US-5561143-A 优先权日:1995-01-25 标题:Aliphatic amino bis-aryl squalene synthase inhibitors 发明人:GRONEBERG ROBERT A; REGAN JOHN R; NEUENSCHWANDER KENT W; SCOTESE ANTHONY C 权利人:RHONE POULENC RORER PHARMA 摘要:This invention relates to a class of novel aliphatic amino bis-aryl compounds containing at least four carbon atoms and an amino group either substituted thereon or incorporated therein and is further linked or bridged to two mono- and/or bicyclic rings. Compounds of this invention reduce levels of serum cholesterol in the body without significantly reducing mevalonic metabolite synthesis. This invention relates also to pharmacological compositions and method of treatment for lowering serum cholesterol levels using the compounds of this invention.
专利号:US-2013059996-A1 优先权日:2010-04-09 标 题 :Boron-Containing PI-Electron Materials Incorporating Formally Aromatic and Neutral Borepin Rings 发明人:TOVAR JOHN DAYTON; CARUSO JR ANTHONY 权利人:TOVAR JOHN DAYTON; CARUSO JR ANTHONY 摘要:The synthesis, functionalization and characterization of borepin-based extended pi-electron molecules is disclosed. Bulky substituents shielded the vacant boron p-orbitals thus allowing synthetic manipulation and purification under ambient lab conditions. The presently disclosed borepin-containing compounds displayed reversible cathodic electrochemistry and can be viewed as n-type analogues to bent acene hydrocarbons.
专利号:US-5534532-A 优先权日:1993-05-21 标题 :Aliphatic amino bis-aryl squalene synthase inhibitors 发明人:GRONEBERG ROBERT A; REGAN JOHN R; NEUENSCHWANDER KENT W; SCOTESE ANTHONY C 权利人:RHONE POULENC RORER PHARMA 摘要:This invention relates to a class of novel aliphatic amino bis-aryl compounds containing at least four carbon atoms and an amino group either substituted thereon or incorporated therein and is further linked or bridged to two mono- and/or bicyclic rings. Compounds of this invention reduce levels of serum cholesterol in the body without significantly reducing mevalonic metabolite synthesis. This invention relates also to pharmacological compositions and method of treatment for lowering serum cholesterol levels using the compounds of this invention.