CAS: 100403-19-8; Ceramides

专利信息

专利号:US-8647848-B2
优先权日:2008-06-13
标题:Enzymatic synthesis of sphingolipids
发明人：HOLLMANN FRANK; THUM OLIVER; TOELLE CHRISTOPH; PROVINZANO ANGELO; KOREVAAR CORNELIS GERRIT NIJS
权利人:HOLLMANN FRANK; THUM OLIVER; TOELLE CHRISTOPH; PROVINZANO ANGELO; KOREVAAR CORNELIS GERRIT NIJS; EVONIK GOLDSCHMIDT GMBH
摘要:The invention relates to the enzymatic synthesis of sphingolipids and compositions that contain sphingolipids from lysosphingolipids and carbonic esters, and to cosmetic, dermatological or pharmaceutical formulations containing said sphingolipids or compositions.

专利号:US-2012003164-A1
优先权日:1998-12-30
标题 :Cosmetic or dermatological composition containing an active agent which stimulates synthesis of the protein hsp 32 in the skin
发明人：NIZARD CARINE; MOREAU MARIELLE; BONTE FREDERIC
权利人:NIZARD CARINE; MOREAU MARIELLE; BONTE FREDERIC; DIOR CHRISTIAN PARFUMS
摘要:A dermatological or cosmetological composition for an external topical administration, included together with pharmaceutically and/or cosmetologically acceptable excipients: at least one UVA-stabilizing and/or UVB-stabilizing screening agent, at least one compound capable of activating the endogenous synthesis of Heat Shock Protein (HSP) 32 or a functional peptide fragment of such a protein, and forskolin or any extract containing it.

专利号:WO-2024222981-A1
优先权日:2023-04-28
标题 :Ester conjugate of sphingolipid and hyaluronan, method of synthesis thereof, composition containing thereof, use of conjugate or composition
发明人：JUHASCIK MARTIN; HUERTA-ANGELES GLORIA; STARMANOVA KATERINA; STEPAN PETR; EXNEROVA ANDREA; NESPOROVA KRISTINA; KOVACIK ANDREJ; BRANDEJSOVA MARTINA; VECEROVA PETRA; POLASKOVA JANA; HERMANNOVA MARTINA; BUFFA RADOVAN; VAGNEROVA HANA; VELEBNY VLADIMIR
权利人:CONTIPRO AS
摘要:The present invention relates to an ester conjugate of sphingolipid and hyaluronan, a composition comprising thereof and its use. Furthermore, it relates to methods of the ester conjugate synthesis.

专利号:US-11529370-B2
优先权日:2017-11-24
标 题 :Use of composition comprising stem cell-derived exosome as effective ingredient in strengthening skin barrier and improving skin barrier function
发明人：YI YONG WEON; CHO BYONG SEUNG
权利人:EXOCOBIO INC
摘要:A composition for strengthening skin barrier or improving skin barrier function is able to improve objective indicators related to the protection of skin barrier, the strengthening of skin barrier, and/or the improvement of skin barrier function. The composition exhibits the effects of increasing the amount of ceramides, dihydroceramides and sphingoid bases, increasing the activities of enzymes that are involved in the synthesis thereof, and decreasing the activities of enzymes that are involved in the degradation thereof. In addition, the composition is able to restore skin barrier function by reducing TSLP, IL-4, and IL-13 which are closely associated with skin barrier damage, and thus interrupting a vicious circle in which the lipids and proteins contributing to skin barrier decrease.

专利号:WO-2023063466-A1
优先权日:2021-10-14
标题:Method for preparing ceramide compound
发明人：CHO SE HYEON; EOM HYUN JI; KIM SEON KI; KIM NA RAE; CHA KYUNG ON
权利人:BJBIOCHEM CO LTD
摘要:Disclosed is a method for preparing a ceramide compound. Specifically, provided is a method for synthesizing ceramide by reaction of phytosphingosine and a methyl ester-based compound represented by chemical formula 2, as starting materials, in the presence of a cyclic amine base-based catalyst. The use of the cyclic amine base-based catalyst enables the synthesis of ceramide at high yield even under relatively mild conditions.

专利号:US-2008081082-A1
优先权日:2000-11-21
标题:Topical Skin Compositions, Their Preparation, and Their Use
发明人：ZIMMERMAN AMY C; DEPPA DEBRA J; O'TOOLE DEBORAH A; MAYNE JAMES R
权利人:ACCESS BUSINES GROUP INTERNAT
摘要:Topical skin compositions include a complex containing components to provide a defense against the various pathway mechanisms of free radicals, reactive oxygen species, reactive nitrogen species, and other oxidizing species on the human body including the skin. The compositions may be administered by topically applying them in an amount to inhibit those mechanisms. The compositions and methods are directed to the prevention of the adverse or detrimental effects of free radicals, reactive oxygen species, reactive nitrogen species, and other oxidizing species on the human body including the skin. Thus, the compositions according to the invention improve barrier function, inhibit elastase and collagenase, and/or promote synthesis of collagen and elastin.