CAS: 901-47-3; Tame

专利信息

专利号:US-5115099-A
优先权日:1988-06-14
标 题:Substrates for determination of enzyme activity and intermediates for synthesis of the substrates as well as process for producing the intermediates
发明人：KUROIWA KATSUMASA; MATSUURA HITOSHI; KATAYAMA KATSUHIRO; NAKATSUYAMA SHUICHI; NAGASAWA TAKESHI; ENDO KOJI
权利人:NITTO BOSEKI CO LTD
摘要:Novel compounds represented by the following formula: ##STR1## wherein A represents a specific amino acid residue are excellent as substrates for determination of enzyme activity such as trypsin, etc. The compounds can be synthesized from novel arginyl-3-tert-alkyloxycarbonyl-4-nitroanilides by a novel process comprising a selective deprotection step whereby the protecting group on the α-amine group of arginine is removed in the presence of a hydrochloric acid, acetic acid and dimethylformamide mixture, but a tert-alkyl protecting group on the --COOH group of the nitroanilide ring is not removed by this step.

专利号:US-4604234-A
优先权日:1983-06-30
标题:Protein having cell growth stimulating action, composition thereof and method for producing the same
发明人：FUJII SETSURO; CHIKAZAWA NOBUMOTO; ARIMA TERUO; FUKUSHIMA MASAKAZU
权利人:SANWA KAGAKU KENKYUSHO CO
摘要:A protein effective in stimulating cell growth activity. The protein has a molecular weight of from 5,000 to about 160,000, is composed predominantly of neutral and acidic amino acids, contains a significant amount of glutamic acid and aspartic acid, and is substantially free of nucleoside phosphotransferase. The protein is useful as wound treatment agent and as promoting agent in the synthesis of DNA. A method of producing the protein and compositions containing the same are also disclosed.

专利号:EP-0513863-A1
优先权日:1988-06-14
标题:Substrates for determination of enzyme activity and intermediates for synthesis of the substrates as well as process for producing the intermediates

专利号:EP-0513863-B1
优先权日:1988-06-14
标题:Substrates for determination of enzyme activity and intermediates for synthesis of the substrates as well as process for producing the intermediates

专利号:EP-0347734-A2
优先权日:1988-06-14
标 题:Substrates for determination of enzyme activity and intermediates for synthesis of the substrates as well as process for producing the intermediates

专利号:JP-H02312598-A
优先权日:1989-05-29
标 题 :Solid phase synthesis of peptides