CAS: 7365-82-4; N-(Carbamoylmethyl)-2-Aminoethanesulfonic Acid

相似化合物

19213-70-8 34730-59-1 107-68-6

专利信息

专利号:US-10501782-B1
优先权日:2014-09-05
标题:Cell-free synthesis of DNA by strand displacement
发明人：PORTER NEIL; ROTHWELL PAUL; EXTANCE JONATHAN
权利人:TOUCHLIGHT IP LTD
摘要:The present invention relates to an improved process for synthesis of DNA, RNA, proteins and like molecules, in particular cell-free enzymatic synthesis of DNA, preferably in large scale. The present invention relates to the synthesis of DNA using strand-displacement replication and the addition of nucleotides to the reaction mixture is controlled, thus controlling yield. The reaction mixture contains a starting amount of nucleotides, polymerase and DNA template, to which further nucleotides are supplied in a controlled manner.

专利号:US-8420848-B2
优先权日:2009-01-09
标题:Process for the synthesis of beta glycerol phosphate
发明人：KULKARNI YASHWANT
权利人:KULKARNI YASHWANT; SIGMA ALDRICH CO LLC
摘要:The present invention provides methods for the preparation of beta glycerol phosphate and its salts. In particular, the invention provides efficient methods for the synthesis of beta glycerol phosphate of high purity.

专利号:US-2023091493-A1
优先权日:2020-02-14
标 题:Dna synthesis yield improvements
发明人：ROTHWELL PAUL; KYSH DANIEL; PORTER NEIL
权利人:TOUCHLIGHT IP LTD
摘要:The present invention relates to an improved process for synthesis of deoxyribonucleic acid (DNA), in particular cell-free enzymatic synthesis of DNA, preferably on a large or industrial scale, with an improved yield and/or with an improved efficiency. The invention requires the use of nucleotide complexes wherein the nucleotide is associated with a mixture of divalent and monovalent cations. Preferably, the divalent cation may be magnesium or manganese.

专利号:WO-2009028973-A1
优先权日:2007-08-31
标 题:Massive production of mycobacterial glucosyl-3-phosphoglycerate synthase and the use of this enzyme as a target for antimycobacterial substances
发明人：SIMOES DA COSTA MILTON; DA SILVA EMPADINHAS NUNO MIGUEL
权利人:BIOCANT PARK CT DE INOVACAO EM; SIMOES DA COSTA MILTON; DA SILVA EMPADINHAS NUNO MIGUE
摘要:The present invention describes the isolation, identification and characterization of a gene (gpgS) and of the function of the corresponding enzyme responsible for the synthesis of glucosyl-3-phosphoglycerate (GpgS), the precursor of glucosylglycerate, a component of the methylglucose polysaccharides from mycobacteria and some closely related bacteria. This gene is conserved among mycobacteria and is essential for the growth of Mycobacterium tuberculosis, the causative agent of tuberculosis. The invention discloses the gpgS gene, processes for production of the enzymes encoded by the genes from Mycobacterium bovis and Mycobacterium smegmatis, the properties of the enzymes, the construction of plasmids that include the genes and of Escherichia coli clones containing these plasmids and that can be used for the large scale production of the enzymes, aiming at the identification or development of specific molecules that can inhibit this enzyme involved in the metabolic pathway leading to the synthesis of the methylglucose polysaccharides from mycobacteria. Therefore the present invention is applicable to the area of the pharmaceutical industry.

专利号:US-2022233673-A1
优先权日:2019-06-04
标 题:METHODS OF PRODUCING SHIGA TOXIN B-SUBUNIT (STxB) MONOMERS AND OLIGOMERS, AND USES THEREOF
发明人：BILLET ANNE; SCHMIDT FRÉDÉRIC; JOHANNES LUDGER; SERVENT DENIS; MOURIER GILLES; TARTOUR ÉRIC; KAY MICHAEL; FULCHER JAMES M
权利人:INST CURIE; CENTRE NAT RECH SCIENT; INST NAT SANTE RECH MED; COMMISSARIAT A LENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES CEA; APHP ASSIST PUBLIQUE HOPITAUX DE PARIS; UNIV PARIS; UNIV OF UTAH RESEARCH FOUDATION; UNIV UTAH RES FOUND
摘要:A method of producing a monomer of a Shiga toxin B-subunit (STxB) protein or of a variant thereof by peptide chemical synthesis, as well as to a method of producing a pentamer of the STxB protein or of the variant thereof. The methods are particularly advantageous as they overcome major issues typically observed in peptide chemical synthesis, including solubility and purity issues.

专利号:US-2008138866-A1
优先权日:2005-03-11
标题 :Process for the Preparation of (R)-4,4-Dialkoxy-Pyran-3-Ols Such as (R)-4,4-Dimethoxy-Pyran-3-Ol
发明人：MOORE JEFFREY C; KOSJEK BIRGIT; NTI-GYABAAH JOSEPH
权利人:MOORE JEFFREY C; KOSJEK BIRGIT; NTI-GYABAAH JOSEPH
摘要:The present invention is concerned with novel processes for the preparation of (R)-4,4-dimethoxy-pyran-3-ol. This compound is useful as an intermediate in the synthesis of compounds which possess pharmacological activity including CCR2 antagonists.