正丙胺置于二硫化碳,三乙胺,Lead(II) Nitrate,硫酸体系中,用 水 作为反应溶剂,化学反应 2.0H,以34%的收率获得产物异氰酸丙酯 参考文献:A Facile And New Approach To Synthesize 2-Amino-4-(4-Amoinophenyl)-1H-1,3-Diazol-1-Yl-Alkylaminomethanethiones 标题:A Facile And New Approach To Synthesize 2-Amino-4-(4-Amoinophenyl)-1H-1,3-Diazol-1-Yl-Alkylaminomethanethiones 摘要:An "Intellectual Connection" Approach To Design A Facile And New Synthesis Of Suitably Substituted 2-Aminoimidazole-Based Precursors Of Expected Antiasthmatic Agents Through A Benzidine Type Of Rearrangement Of 2-Phenylazoimidazole And Subsequent Coupling Of The Product Thus Obtained With Alkylisothiocyanates Involving A Degenerative Operation,Thereby Improving The Time Frame Of The Overall Synthetic Sequence,Is Reported. The Alkylisothiocyanates Required In This Synthetic Sequence Are Prepared Using A Best Combination Of Reported Methods. The Compounds Reported Here Can Be Used To Produce Derivatives Of Other Biological Agents. DOI:10.1007/s00044-007-9003-1
专利号:US-5629394-A 优先权日:1992-12-17 标 题 :Direct synthesis by living cationic polymerization of nitrogen-containing polymers 发明人:CHERADAME HERVE M; CHEN FRANK J; STANAT JON E R; NGUYEN HUNG A; TABAR BEHROOZ R 权利人:EXXON CHEMICAL PATENTS INC 摘要:A method is provided for the direct synthesis by living cationic polymerization of novel polymeric materials functionalized with desirable nitrogen-containing functional groups such as terminal azido, cyano, carbonylamino, cyanato, thiocyanato or thiocarbonylamino groups. Polymerization and functionalization occur in a substantially simultaneous manner. All necessary reactants for the functionalization are present when polymerization is initiated. The nitrogen-containing functional group is provided as a part of a molecule having a release moiety which is preferably resonance stabilized or a tertiary alkyl type and which acts to aid the nitrogen-containing species in functioning as a leaving group.
专利号:US-4780557-A 优先权日:1987-08-26 标题:Method of preparation of (substituted-thio)alkyl isothiocyanates 发明人:SUTHERLAND GEORGE W; KUHN STEPHEN J 权利人:DOW CHEMICAL CO 摘要:A one-step process for the preparation of (substituted-thio)alkyl isothiocyanates in high yield comprising contacting a haloalkyl sulfide with a thiocyanate salt in the absence of a catalyst under reaction conditions sufficient to produce the desired (substituted-thio)alkyl isothiocyanate is disclosed. Examples of compounds produced by this process include CH 3 SCH 2 CH 2 NCS and n-C 6 H 13 SCH 2 CH 2 NCS. n The compounds produced by this process are useful as intermediates in the synthesis or ore flotation chemicals such as substituted thiocarbamates or thioureas.
专利号:US-5336745-A 优先权日:1988-06-28 标题 :Terminally-substituted polymeric compositions from cationically polymerizable monomers and initiators 发明人:CHERADAME HERVE M; LUNDBERG ROBERT D; CHEN FRANK J; HABIMANA JEAN DE LA CROIS 权利人:EXXON CHEMICAL PATENTS INC 摘要:A method is provided for the direct synthesis of novel polymeric materials functionalized with desirable nitrogen-containing functional groups such as terminal azido, cyano, carbonylamino or thiocarbonylamino groups. Polymerization and functionalization occur in a substantially simultaneous manner. All necessary reactants for the functionalization are present when polymerization is initiated. The nitrogen-containing functional group is provided as a part of a molecule having a release moiety which is preferably resonance stabilized or of tertiary alkyl type and which acts to aid the nitrogen-containing species in functioning as a leaving group.
专利号:JP-H0284403-A 优先权日:1988-06-28 标题 :Direct synthesis of nitrogen-containing polymers by cationic polymerization
专利号:EP-2864334-A1 优先权日:2012-06-25 标题:Synthesis of thiosemicarbazides and triazoles derived from etodolac
专利号:WO-2014003694-A1 优先权日:2012-06-25 标题 :Synthesis of thiosemicarbazides and triazoles derived from etodolac