CAS: 628-30-8; Isothiocyanic Acid Propyl Ester

该化合物是属于异硫酸盐家族的挥发性有机硫化合物,其特征是其发光的气味,通常来自十字架蔬菜或合成工业用途,该化合物由于异硫氰酸盐组(-N=C=S)的电生殖性而表现出显著的反活性,使其在有机合成中有用,并成为农用化学或药物的前体,其抗微生物和杀虫特性在作物保护中很受关注.Propyl 异硫氰酸盐还因其独特的尖性芳香而被用于口味和香味工业.适当的处理至关重要,因为它可能刺激皮肤,眼睛和粘膜.

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欧盟法规

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CAS号107-10-8 丙胺 | CAS号75-15-0 二硫化碳 | CAS号463-71-8 硫光气 | CAS号84050-92-0 N1,N3-dipropyl-... | CAS号83962-15-6 ethyl propylcar... | CAS号64221-09-6 propyl-dithi°Ca... | CAS号28249-05-0 propyl-dithi°Ca... | CAS号108168-83-8 4-propyl-5-prop... | CAS号623-95-0 1,3-二丙基脲 | CAS号821-79-4 N,N'-di-n-propy... | CAS号64671-67-6 3-methyl-4-prop... | CAS号927-67-3 正丙基硫脲 | CAS号21076-68-6 1-(dimethylamin... | CAS号32093-90-6 Thiourea,N-2-ox... | CAS号32900-00-8 3-methyl-1-prop... | CAS号110-78-1 异氰酸丙酯

合成工艺路线路线简述

    正丙胺置于二硫化碳,三乙胺,Lead(II) Nitrate,硫酸体系中,用 水 作为反应溶剂,化学反应 2.0H,以34%的收率获得产物异氰酸丙酯
    参考文献:A Facile And New Approach To Synthesize 2-Amino-4-(4-Amoinophenyl)-1H-1,3-Diazol-1-Yl-Alkylaminomethanethiones
    标题:A Facile And New Approach To Synthesize 2-Amino-4-(4-Amoinophenyl)-1H-1,3-Diazol-1-Yl-Alkylaminomethanethiones
    摘要:An "Intellectual Connection" Approach To Design A Facile And New Synthesis Of Suitably Substituted 2-Aminoimidazole-Based Precursors Of Expected Antiasthmatic Agents Through A Benzidine Type Of Rearrangement Of 2-Phenylazoimidazole And Subsequent Coupling Of The Product Thus Obtained With Alkylisothiocyanates Involving A Degenerative Operation,Thereby Improving The Time Frame Of The Overall Synthetic Sequence,Is Reported. The Alkylisothiocyanates Required In This Synthetic Sequence Are Prepared Using A Best Combination Of Reported Methods. The Compounds Reported Here Can Be Used To Produce Derivatives Of Other Biological Agents.
    DOI:10.1007/s00044-007-9003-1

    海关参考信息

    专利信息


    专利号:US-5629394-A
    优先权日:1992-12-17
    标 题 :Direct synthesis by living cationic polymerization of nitrogen-containing polymers
    发明人:CHERADAME HERVE M; CHEN FRANK J; STANAT JON E R; NGUYEN HUNG A; TABAR BEHROOZ R
    权利人:EXXON CHEMICAL PATENTS INC
    摘要:A method is provided for the direct synthesis by living cationic polymerization of novel polymeric materials functionalized with desirable nitrogen-containing functional groups such as terminal azido, cyano, carbonylamino, cyanato, thiocyanato or thiocarbonylamino groups. Polymerization and functionalization occur in a substantially simultaneous manner. All necessary reactants for the functionalization are present when polymerization is initiated. The nitrogen-containing functional group is provided as a part of a molecule having a release moiety which is preferably resonance stabilized or a tertiary alkyl type and which acts to aid the nitrogen-containing species in functioning as a leaving group.

    专利号:US-4780557-A
    优先权日:1987-08-26
    标题:Method of preparation of (substituted-thio)alkyl isothiocyanates
    发明人:SUTHERLAND GEORGE W; KUHN STEPHEN J
    权利人:DOW CHEMICAL CO
    摘要:A one-step process for the preparation of (substituted-thio)alkyl isothiocyanates in high yield comprising contacting a haloalkyl sulfide with a thiocyanate salt in the absence of a catalyst under reaction conditions sufficient to produce the desired (substituted-thio)alkyl isothiocyanate is disclosed. Examples of compounds produced by this process include CH 3 SCH 2 CH 2 NCS and n-C 6 H 13 SCH 2 CH 2 NCS. n The compounds produced by this process are useful as intermediates in the synthesis or ore flotation chemicals such as substituted thiocarbamates or thioureas.

    专利号:US-5336745-A
    优先权日:1988-06-28
    标题 :Terminally-substituted polymeric compositions from cationically polymerizable monomers and initiators
    发明人:CHERADAME HERVE M; LUNDBERG ROBERT D; CHEN FRANK J; HABIMANA JEAN DE LA CROIS
    权利人:EXXON CHEMICAL PATENTS INC
    摘要:A method is provided for the direct synthesis of novel polymeric materials functionalized with desirable nitrogen-containing functional groups such as terminal azido, cyano, carbonylamino or thiocarbonylamino groups. Polymerization and functionalization occur in a substantially simultaneous manner. All necessary reactants for the functionalization are present when polymerization is initiated. The nitrogen-containing functional group is provided as a part of a molecule having a release moiety which is preferably resonance stabilized or of tertiary alkyl type and which acts to aid the nitrogen-containing species in functioning as a leaving group.

    专利号:JP-H0284403-A
    优先权日:1988-06-28
    标题 :Direct synthesis of nitrogen-containing polymers by cationic polymerization

    专利号:EP-2864334-A1
    优先权日:2012-06-25
    标题:Synthesis of thiosemicarbazides and triazoles derived from etodolac

    专利号:WO-2014003694-A1
    优先权日:2012-06-25
    标题 :Synthesis of thiosemicarbazides and triazoles derived from etodolac
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    合成参考文献


    摘要:Keller, P. A., Science of Synthesis, (2005) 15, 363.
    摘要:Braverman, S.; Cherkinsky, M.; Birsa, M. L., Science of Synthesis, (2005) 18, 199.
    摘要:Sato, S.; Furukawa, N., Science of Synthesis, (2005) 18, 910.
    摘要:Lebel, H., Science of Synthesis, (2005) 22, 162.
    摘要:Schobert, R.; Gordon, G. J., Science of Synthesis, (2004) 27, 1045.
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