CAS: 6232-11-7; Methyl 4-(Aminomethyl)Benzoate Hydrochloride

上下游产品

methyl 4-[N-(tert-butoxycarbonyl)aminomethyl]benzoate methanol p-aminomethylbenzoic acid 4-(tert-Butoxycarbonylaminomethyl)benzoic acidN-(4-methoxycarbonylbenzyl)-3-(3-indolyl)propanamide methyl 4-((prop-2-yn-1-ylamino)methyl)benzoate methyl 4-(N,N-dimethylaminomethyl)benzoate methyl>-1-methyl-1H-indole-3-carboxamide2-chloro-N-(4-methoxycarbonyl)phenylmethyl-1-methyl-1H-indole-3-carboxamide

4-氨甲基苯甲酸置于甲醇,氯化亚砜体系中,用98.3%的收率获得产物4-氨甲基苯甲酸甲酯盐酸盐
参考文献:尺寸互补的轮烷交联用于超分子网络的稳定和降解
标题:尺寸互补的轮烷交联用于超分子网络的稳定和降解
摘要:分解:准备了由轮烷交联剂形成的凝胶,端基的大小与车轮组件的大环腔互补(参见图片).将网络结构保持在极性有机溶剂中或在碱的存在下以防止氢键键合.阴离子交换可实现凝胶的选择性和高效去交联.
DOI:10.1002/anie.201008020

专利信息

专利号:US-11485721-B2
优先权日:2017-11-21
标 题:Method for the metal-free preparation of a biaryl by a photosplicing reaction and their uses
发明人：KLOSS FLORIAN; NEUWIRTH TONI; HAENSCH VEIT; HERTWECK CHRISTIAN
权利人:LEIBNIZ INST FUER NATURSTOFF FORSCHUNG UND INFEKTIONSBIOLOGIE E V HANS KNOELL INST HKI; LEIBNIZ INST FUER NATURSTOFF FORSCHUNG UND INFEKTIONSBIOLOGIE E V HANS KNOELL INST
摘要:The present invention relates to a method for the metal-free preparation of a biaryl compound by a photosplicing reaction and its use in the preparation of chemical compounds, preferably of active ingredients e.g. in the fields of pharmaceuticals and agrochemicals. In particular, it refers to a method for the regiocontrolled preparation of a biaryl compound of formula (I): Ar—Ar′ by photochemically reacting a precursor compound of formula (II): Ar—L—Ar′ to form a biaryl compound of general formula: Ar—L—Ar′(II)→Ar—Ar′ (I) wherein Ar and Ar′, independently of each other, represent an unsubstituted or substituted C6-C20 aryl group or a heteroaryl group with 5-20 ring atoms selected from carbon, nitrogen, oxygen and sulfur, and L represents a group —X—Y—Z— as defined herein. The biaryl compounds are generally suitable as intermediates or key building blocks in a very broad spectrum of organic chemical syntheses and their respective utilities. Their use within the field of synthesis of active ingredients is an aspect of the invention, and their use in the preparation of pharmaceutically active ingredients is particularly preferred.

专利号:EP-2084147-B1
优先权日:2006-08-29
标 题:Heterocyclic fxr binding compounds
发明人：KREMOSER CLAUS; DEUSCHLE ULRICH; ABEL ULRICH; SCHULZ ANDREAS
权利人:PHENEX PHARMACEUTICALS AG
摘要:The present invention relates to compounds which bind to the NR1H4 receptor (FXR) and act as agonists or partial agonists of the NR1H4 receptor (FXR). The invention further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding of said nuclear receptor by said compounds, and to a process for the synthesis of said compounds.

专利号:CN-120025338-A
优先权日:2025-03-11
标 题:Synthesis method of three H1FX selective inhibitors and application of three H1FX selective inhibitors in preparation of antitumor drugs