CAS: 610-30-0; 2,4-Dinitrobenzoic Acid

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CAS号34103-64-5 N-((5R)-2c-hydr... | CAS号20195-22-6 2,4-dinitrobenz... | CAS号121-14-2 2,4-二硝基甲苯标准溶液 | CAS号33672-95-6 ethyl 2,4-dinit... | CAS号528-75-6 2,4-二硝基苯甲醛 | CAS号18959-19-8 4-nitrophenyl 2... | CAS号139361-27-6 (4-methylphenyl... | CAS号139361-28-7 4-chlorophenyl ... | CAS号20195-22-6 2,4-dinitrobenz... | CAS号18436-61-8 1-乙炔-2,4-二硝基苯 | CAS号18959-17-6 2,4-二硝基苯甲酸甲酯 | CAS号99-65-0 间二硝基苯 | CAS号619-17-0 2-氨基-4-硝基苯甲酸 | CAS号610-36-6 4-氨基-2-硝基苯甲酸 | CAS号74230-08-3 4-羟基-2-硝基苯甲酸 | CAS号129459-89-8 [(2,4-dinitrobe... | CAS号139361-27-6 (4-methylphenyl... | CAS号108-45-2 间苯二胺

📜1-[2-(2,4-二硝基苯基)乙基]-2,4-二硝基苯置于二环己烷并-18-冠醚-6,Potassium Permanganate体系中,用 苯 作为反应溶剂,化学反应 5.0H,以53.86%的收率获得产物2,4-二硝基苯甲酸
参考文献:一种合成2,4-二硝基苯甲酸的方法
标题:一种合成2,4-二硝基苯甲酸的方法
摘要:本发明涉及有机中间体制备技术领域,具体涉及一种合成2,4-二硝基苯甲酸的方法,包括以联苄为原料经硝化得到四硝基联苄,四硝基联苄再经氧化得到2,4-二硝基苯甲酸.本发明提供了一种合成2,4-二硝基苯甲酸的全新原料路线和工艺方法,其硝化与氧化反应均在常温下进行,具有条件温和,能耗低,产物易纯化的优点.

专利信息

专利号:US-7897758-B2
优先权日:2005-04-27
标题 :Activators for oligonucleotide and phosphoramidite synthesis
发明人：WOLTER ANDREAS; LEUCK MICHAEL
权利人:SIGMA ALDRICH CO
摘要:The present invention discloses novel methods for the synthesis of oligonucleotides and nucleoside phosphoramidites. The methods are based on employing aryl-substituted 5-phenyl-1H-tetrazoles with perfluoroalkyl groups on the aromatic ring as activators. In one aspect the novel activators are used in the synthesis of oligonucleotides via the phosphoramidite approach. In this aspect the activators are highly efficient and can be applied with very short coupling times. In a further aspect, the activators of the invention are used in the synthesis of phosphoramidites through the reaction of nucleosides comprising a free hydroxyl group with phosphitylating agents. In this aspect the activators provide very pure phosphoramidites under mild conditions. The activators of the invention are further characterized by being highly soluble, non-hygroscopic and non-hazardous.

专利号:US-5648489-A
优先权日:1994-05-17
标题 :Syntheses of acyclic guanine nucleosides
发明人：CHU CHUNG K; DU JINFA; WANG CHUNGUANG
权利人:UNIV GEORGIA
摘要:A method is provided for the synthesis of synthesis of acyclic purine nucleosides, particularly 9-(2-hydroxy-ethoxymethyl)-guanine (acyclovir) and 9-[(1,3-dihydroxy-2-propoxy)methyl]guanine ('DHPG') where the N2,N9-diprotected guanine is reacted with CH3C(O)OCH2O(CH2)2)OC(O)CH3 or 2-acetoxymethoxy-1,3-diacetoxypropane, respectively, in the presence of a mixture of an acid and acetic anhydride, or in the presence of an acid, where the acid can be phosphoric acid or polyphosphoric acid.

专利号:US-3555015-A
优先权日:1968-09-17
标 题 :Process for the preparation of gona-1,3,5(10),7-tetraenes
发明人：STEIN REINHARDT P; BUZEY GEORGE C JR; SMITH HERCHEL
权利人:AMERICAN HOME PROD
摘要:TREATMENT OF A 13-ALKYLGONA-1,3,5(10),8-TETRAENE WITH ORGANIC PERACID RESULTS IN THE FORMATION OF A CORRESPONDING 8,9-EPOXY-13-ALKYLGONA-1,3,5(10)-TRIENE, WHICH UPON TREATMENT WITH ACID, IS RING-OPENED AND REARRANGED TO THE CORRESPONDING 13-ALKYLGONA-1,3,5(10),9(11)-TETRAEN-8-OL. CATALYTIC HYDROGENATION THEN AFFORDS THE CORRESPONDING 13-ALKYLGONA-1,3,5(10)-TRIEN-8-OL WHICH UPON DEHYDRATION GIVES THE CORRESPONDING 13-ALKYLGONA-1,3,5(10),7-TETRAENE. THERE IS THUS PROVIDED A ROUTE TO THE SYNTHESIS OF EQUILIN AND RELATED COMPOUNDS.

专利号:US-5132419-A
优先权日:1989-10-03
标题 :Process for the preparation of 7-amino-3-((z)-1-propen-1yl)-3-cephem-4-carboxylic acid
发明人：LANZ JOACHIM; NAAB PAUL; ROSENTRETER ULRICH
权利人:BAYER AG
摘要:(7-APCA) having the formula (I) ##STR1## which is an important synthesis intermediate in the preparation of cephalosporin-like antibiotics, is prepared by treating a compound of the formula (II) ##STR2## in which R 1 and R 2 represent alkyl, aryl and aralkyl radicals, with a strong protonic acid or with a Lewis acid. Compound (II) is prepared by adding triphenylphosphine and alkali metal iodide to a compound of the formula (VI) ##STR3## then reacting with acetaldehyde in base. Compound (VI) is prepared by treating a compound of the formula (VII) ##STR4## with a base in a polar solvent at -70° C. to 0° C. Compound (VII) is prepared by treating a compound of the formula (VIII) ##STR5## with a chlorinating agent in an organic solvent.

专利号:US-9217012-B2
优先权日:2009-04-08
标题 :Inhibitors of protein tyrosine phosphatases
发明人：ZHANG ZHONG-YIN; ZHANG SHENG
权利人:ZHANG ZHONG-YIN; ZHANG SHENG; UNIV INDIANA RES & TECH CORP
摘要:Disclosed herein are compounds that selectively inhibit members of the PTP family of enzymes. Synthesized compounds demonstrated selective inhibition of TC-PTP. Also provided are methods of using the compounds and formulations containing the compounds. Also described is a fluorescence-tagged combinatorial library synthesis and screening method. And methods of using these compounds to effect enzyme activity both in cells and in vitro as well as method of using these compounds to treat diseases in human and animals.

专利号:CN-117659327-A
优先权日:2023-12-13
标题 :Method for catalytic synthesis of novel polyurethane elastomer and application thereof