CAS: 60546-10-3; (6S,7R,10S,18S,19S)-7,19-Dihydroxy-12,13,14-Trimethoxy-6,7,18,19-Tetramethyl-6,7-Dihydro-10H-10,15-Propano[1,3]Dioxolo[4',5':5,6]Benzo[1,2-G]Benzo[i][1,6]Dioxacycloundecin-8(5H)-One
- 英文名称(6S,7R,10S,18S,19S)-7,19-Dihydroxy-12,13,14-Trimethoxy-6,7,18,19-Tetramethyl-6,7-Dihydro-10H-10,15-Propano[1,3]Dioxolo[4',5':5,6]Benzo[1,2-G]Benzo[i][1,6]Dioxacycloundecin-8(5H)-One
- 中文名称戈米辛D
- IUPAC名称(6S,7R,10S,18S,19S)-7,19-dihydroxy-12,13,14-trimethoxy-6,7,18,19-tetramethyl-6,7-dihydro-10H-10,15-propano[1,3]dioxolo[4',5':5,6]benzo[1,2-g]benzo[i][1,6]dioxacycloundecin-8(5H)-one
- 其它别名Gomisin D; 5,13-(Epoxybutanoxy)Benzo[3,4]Cycloocta[1,2-F][1,3]Benzodioxol-18-One,5,6,7,8-Tetrahydro-6,17-Dihydroxy-1,2,3-Trimethoxy-6,7,16,17-Tetramethyl-,(5S,6S,7S,13Ar,16R,17R)-; (11S,12R,15S,24S,25S)-12,25-Dihydroxy-18,19,20-Trimethoxy-11,12,24,25-Tetramethyl-4,6,9,14-Tetraoxapentacyclo[13.7.3.0Sup3,7Sup.0Sup8,22Sup.0Sup16,21Sup]Pentacosa-1(22),2,7,16,18,20-Hexaen-13-One; 7,19-Dihydroxy-12,13,14-Trimethoxy-6,7,18,19-Tetramethyl-6,7-Dihydro-5H-10,15-Propano[1,3]Dioxolo[4',5':5,6]Benzo[1,2-G]Benzo[i][1,6]Dioxacycloundecin-8(10H)-One; Gomisin D, 10 Mm In Dmso
- CAS编号60546-10-3
- MFCD编号:MFCD32004198
- 分子式:C28H34O10分子量:530.57
- 产品CID: 1581666
- 产品分类天然产物 → 木脂素
物理性质
MSDS等安全信息
- GHS符号GHS07
- 警示词Warning
- 危险描述H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
- 防范说明P264Thoroughly clean after treatmentP280Wear protective gloves/Wear protective clothing/Wear protective goggles/Wear a protective maskP305If it enters the eyesP351Rinse carefully with water for a few minutesP338Remove the contact lens(If any)And easy to operate,Continue flushingP337If eye irritation persistsP313Obtain medical advice/care
- 安全声明H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
合成工艺路线路线简述
海关参考信息
- 2902600000-乙苯
2905122000-异丙醇
2905143000-叔丁醇
2905310000-1,2-乙二醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
1: Song Y, Shan B, Zeng S, Zhang J, Jin C, Liao Z, Wang T, Zeng Q, He H, Wei F, Ai Z, Su D. Raw and wine processed Schisandra chinensis attenuate anxiety like behavior via modulating gut microbiota and lipid metabolism pathway. J Ethnopharmacol. 2020 Sep 29;266:113426. doi: 10.1016/j.jep.2020.113426. Epub ahead of print. 24(7):1335. doi: 10.3390/molecules24071335.
3: Zheng X, Feng F, Jiang X, Qiu J, Cai X, Xiang Z. A Rapid UPLC-MS Method for Quantification of Gomisin D in Rat Plasma and Its Application to a Pharmacokinetic and Bioavailability Study. Molecules. 2019 Apr 10;24(7):1403. doi: 10.3390/molecules24071403.
4: Szopa A, Dziurka M, Warzecha A, Kubica P, Klimek-Szczykutowicz M, Ekiert H. Targeted Lignan Profiling and Anti-Inflammatory Properties of Schisandra rubriflora and Schisandra chinensis Extracts. Molecules. 2018 Nov 27;23(12):3103. doi: 10.3390/molecules23123103.
合成参考文献
参考文献:10.1248/cpb.40.1191
摘要:SAKURAI H, NIKAIDO T, OHMOTO T, IKEYA Y, MITSUHASHI H. Inhibitors of cAMP Phosphodiesterase in Medicinal Plants. Part XVIII. Inhibitors of Adenosine 3',5'-Cyclic Monophosphate Phosphodiesterase from Schisandra chinensis and the Structure Activity Relationship of Lignans. Chem. Pharm. Bull. 1992;40(5):1191–5. doi: 10.1248/cpb.40.1191.
📝 需求与反馈
尽可能描述清楚需求与问题信息
