专利号:US-2025179012-A1 优先权日:2022-03-04 标 题:Synthesis of sulfur(vi) compounds and reagents for same 发明人:LOPCHUK JUSTIN MATTHEW; SHULTZ ZACHARY 权利人:H LEE MOFFITT CANCER CT & RES 摘要:This disclosure provides reagents and processes for the synthesis of organic compounds, more particularly reagents and processes for the asymmetric synthesis of sulfur (VI) containing organic compounds.
专利号:US-8642766-B2 优先权日:2008-05-05 标题 :Synthesis of (+) cortistatin A and related compounds 发明人:SHENVI RYAN A; GUERRERO CARLOS A; SHI JUN; LI CHUANG-CHUANG; BARAN PHIL S 权利人:SHENVI RYAN A; GUERRERO CARLOS A; SHI JUN; LI CHUANG-CHUANG; BARAN PHIL S 摘要:An in vitro synthesis of (+) cortistatin A from readily available precursors is disclosed, as are the syntheses of related 17-aryl substituted compounds, the 17-aryl substituted compounds themselves and novel compounds useful in their preparation.
专利号:US-5554753-A 优先权日:1993-08-25 标 题:Catalytic enantioselective synthesis of α-amino acid derivatives by phase-transfer catalysis 发明人:O'DONNELL MARTIN J; WU SHENGDE; ESIKOVA IRENA; MI AIQIAO 权利人:INDIANA UNIVERSITY FOUNDATION 摘要:Described are improved processes for the enantioselective synthesis of α-amino acids which involve combinations of solvents, highly-mixed and low-temperature reaction conditions, and novel catalysts. Also described are novel catalysts and precursors to α-amino acid derivatives.
专利号:US-9982005-B2 优先权日:2013-04-04 标 题 :Macrolides and methods of their preparation and use 发明人:MYERS ANDREW G; SEIPLE IAN BASS; ZHANG ZIYANG 权利人:HARVARD COLLEGE 摘要:Provided herein are methods of preparing macrolides by the coupling of an eastern and western half, followed by macrocyclization, to provide macrolides, including both known and novel macrolides. Intermediates in the synthesis of macrolides including the eastern and western halves are also provided. Pharmaceutical compositions and methods of treating infectious diseases and inflammatory conditions using the inventive macrolides are also provided. A general diastereoselective aldol methodology used in the synthesis of the western half is further provided.
专利号:US-9102650-B2 优先权日:2014-08-08 标 题:Synthesis of new anti-inflammatory compound 发明人:XU YONG 权利人:XU YONG 摘要:According to embodiments of present disclosure, a method to produce a compound of Formula 19 is provided. Using this method, the compound of Formula 19 may be produced effectively.
专利号:US-12076715-B1 优先权日:2021-04-15 标 题:Synthesis and characterization of air-stable iron-based catalysts for Suzuki-Miyaura cross-coupling reactions of alkyl halides and aryl boronic esters 发明人:WONG ALEXANDER; BYERS JEFFERY 权利人:THE TRUSTEES OF BOSTON COLLEGE 摘要:This disclosure relates to novel catalysts for Suzuki-Miyaura cross-coupling reactions, the use thereof, and the methods of making the same.
摘要:Petasis, N. A., Science of Synthesis, (2010) 47, 220. 摘要:Li, H.; Mazet, C., Science of Synthesis Knowledge Updates, (2015) 2, 21. 摘要:Inoue, S.; Driess, M., Science of Synthesis Knowledge Updates, (2012) 4, 234. 摘要:Primer, D. N.; Molander, G. A., Science of Synthesis, (2019) , 326. 摘要:Maestri, G.; Serafino, A., Science of Synthesis, (2021) , 656.