CAS: 33924-48-0; Methyl 5-Chloro-2-Methoxybenzoate

该化合物是一种属于苯甲酸酯类别的有机化合物.该化合物具有一种含有甲氧基(-OCH3)的苯甲酸核心和一个在芳香环上特定位置的氯替代物(-Cl).该化合物的典型特征是其有机溶剂中的中等溶性以及水中的有限溶性,这在许多芳香酯中很常见.氯和甲基氧组的存在可以影响其回活动性和极性,使其在各种化学应用中有用,包括作为有机合成的中间体.此外,该化合物可能展示生物活动,这可能对制药研究感兴趣.其分子结构有助于其在农业化学品和调味剂中的潜在应用.应当参考安全数据,以便处理和接触任何化学物质时参考安全数据.

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MSDS等安全信息

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

CAS号3438-16-2 5-氯-2-甲氧基苯甲酸 | CAS号29568-33-0 5-氯-2-甲氧基苯甲酰氯 | CAS号33977-11-6 5-氯-2-甲氧基苯甲酸肼 | CAS号7035-10-1 5-氯-2-甲氧苄基醇 | CAS号64353-00-0 5-chloro-2-meth...

合成工艺路线路线简述

    📜5-氯代水杨酸置于potassium Carbonate,硫酸二甲酯体系中,用 丙酮 作为反应溶剂,以23.10 G (99%)的收率获得产物5-氯-2-甲氧基苯甲酸甲酯
    参考文献:Novel Substituted 3H-1,2,3,5-Oxathiadiazole 2-Oxides Useful As
    标题:Novel Substituted 3H-1,2,3,5-Oxathiadiazole 2-Oxides Useful As
    摘要:本发明涉及新型的取代3H-1,2,3,5-噁硫二唑-2-氧化物,以及其制备方法,化合物的使用方法和相关的药物组合物.这些化合物具有药理特性,使它们对于治疗糖尿病及相关疾病有益.

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    专利信息


    专利号:US-10005720-B2
    优先权日:2013-04-05
    标题:Compounds useful for the treatment of metabolic disorders and synthesis of the same
    发明人：SEXTON JONATHAN Z; BRENMAN JAY E; MUSSO DAVID L
    权利人:NORTH CAROLINA CENTRAL UNIV; UNIV NORTH CAROLINA CHAPEL HILL
    摘要:The present invention provides compounds of Formula (I): wherein variables X, Y, Z and R1 are as described herein. Some of the compounds described herein are glutamate dehydrogenase activators. The invention is also directed to pharmaceutical compositions comprising these compounds, uses of these compounds and compositions in the treatment of metabolic disorders as well as synthesis of the compounds.

    专利号:US-2018370905-A1
    优先权日:2013-04-05
    标题:Compounds Useful for the Treatment of Metabolic Disorders and Synthesis of the Same

    专利号:US-2016046560-A1
    优先权日:2013-04-05
    标题 :Compounds useful for the treatment of metabolic disorders and synthesis of the same

    专利号:WO-2014165816-A1
    优先权日:2013-04-05
    标 题 :Compounds useful for the treatment of metabolic disorders and synthesis of the same

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    主要参考文献

    参考标题:Room Temperature C(Sp2)-H Oxidative Chlorination Via Photoredox Catalysis
    作者:Lei Zhang,Xile Hu
    摘要:Catalysis Has Been Developed To Achieve Oxidative C-H Chlorination Of Aromatic Compounds Using Nacl As The Chlorine Source And Na2S2O8 As The Oxidant. The Reactions Occur At Room Temperature And Exhibit Exclusive Selectivity For C(Sp2)-H Bonds Over C(Sp3)-H Bonds. The Method Has Been Used For The Chlorination Of A Diverse Set Of Substrates, Including The Expedited Synthesis Of Key Intermediates To Bioactive

    合成参考文献


    摘要:Ros, A.; Fernández, R.; Lassaletta, J. M., Science of Synthesis: Catalytic Transformations via CH Activation, (2015) 2, 417.
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