1,6-己二醇置于吡啶盐酸盐体系中,化学反应 2.0H,反应生成6-氯-1-己醇 参考文献:转化比较聚氯乙烯和溴化吡啶鎓多反应树脂:Cas De L'Hedioldiol-1,6 1 标题:转化比较聚氯乙烯和溴化吡啶鎓多反应树脂:Cas De L'Hedioldiol-1,6 1 摘要:氯化吡啶鎓和溴化物通过复杂的多反应链过程与1,6-己二醇反应,主要提供不饱和烃,环醚,不饱和卤化物和不饱和醇.5-己烯-1-醇和1-己醇在相同条件下经历的相似转化表明了有关该机理的几种假设.来自13 C NMR数据的一些原始分配涉及确定产物的结构. Doi:10.1016/0040-4020(77)80426-2
专利号:US-3943157-A 优先权日:1971-07-26 标题 :Synthesis of codling moth attractant 发明人:HENRICK CLIVE A; SIDDALL JOHN B 权利人:ZOECON CORP 摘要:Sterospecific synthesis of an attractant for the codling moth by reacting sorbic aldehyde with an organo-metallic reagent to yield a 1-ether of trans-8-trans-10-dodecadiene-1,7-diol which is reduced via a 7-sulfonic acid ester to yield an ether of trans-8-trans-10-dodecadiene-1-ol and hydrolyzed to trans-8-trans-10-dodecadien-1-ol. ##SPC1##
专利号:US-2013302247-A1 优先权日:2012-05-09 标 题:Synthesis of fluoroarachidonic acid and methods of use thereof 发明人:PICHIKA RAMAIAH; ECKELMAN WILLIAM C; RAPOPORT STANLEY I; TAHA AMEER; KOTTA KISHORE 权利人:US HEALTH; UNIV CALIFORNIA 摘要:There are provided, inter alia, methods for diagnosis of the extent of neuroinflammation in a subject. The methods include administering an 18 F-labeled arachidonic acid to a subject in need thereof, obtaining a positron emission tomography (PET) scan of the subject, and determine the extent of neuroinflammation from the PET scan. There are provided, inter alia, methods of synthesis of reagents useful for the production of an 18 F-labeled arachidonic acid.
专利号:US-2013184465-A1 优先权日:2010-09-30 标 题:Process for the synthesis of thio-triazolo-group containing compounds 发明人:DOCHNAHL MAXIMILIAN; KEIL MICHAEL; GEBHARDT JOACHIM; VOGELBACHER UWE JOSEF; RACK MICHAEL 权利人:DOCHNAHL MAXIMILIAN; KEIL MICHAEL; GEBHARDT JOACHIM; VOGELBACHER UWE JOSEF; RACK MICHAEL; BASF SE 摘要:The present invention relates to a process using specific magnesium reagents for providing thio-triazolo group-containing compounds and for the synthesis of precursors therefor. The invention furthermore relates to intermediates and to their preparation.
专利号:EP-1641729-B1 优先权日:2003-07-09 标题:Use of functionalized onium salts as a soluble support for organic synthesis 发明人:VAULTIER MICHEL; GMOUH SAID; HASSINE FATIMA 权利人:CENTRE NAT RECH SCIENT; UNIV RENNES 摘要:The invention relates to the use of a onium salt functionalized by at least one organic function, as a soluble support, in the presence of at least one organic solvent, for organic synthesis of a molecule, in a homogenous phase, by at least one transformation of said organic function. The onium salt enables the synthesized molecule to be released. The onium salt is present in liquid or solid form at room temperature and corresponds to formula A1+, X1-, wherein A1+ represents a cation and X1- represents an anion.
专利号:US-7147800-B2 优先权日:2001-01-23 标题 :Selective ether cleavage synthesis of liquid crystals 发明人:WELLINGHOFF STEPHEN T; HANSON DOUGLAS P 权利人:SOUTHWEST RES INST 摘要:A method for making platform molecules comprising: reacting 4-alkoxy benzoyl chloride with R2-hydroquinone under first conditions effective to produce bis 1,4[4-alkoxy-benzoyloxy]-R2-phenylene comprising bis terminal alkoxy groups wherein R2 is a bulky organic group; and, subjecting the bis 1,4[4-alkoxy-benzoyloxy]-R2-phenylene to second conditions effective to selectively cleave the bis terminal alkoxy groups to produce a solution comprising complexes comprising diphenolic platform molecules comprising bis terminal hydroxyl groups, the second conditions also being effective to precipitate the complexes out of the solution.
专利号:US-4912253-A 优先权日:1988-06-06 标题 :Method for the preparation of an unsaturated alcohol or ester thereof 发明人:FUKUMOTO TAKEHIKO; YAMAMOTO AKIRA 权利人:SHINETSU CHEMICAL CO 摘要:An efficient method is proposed for the synthesis of an unsaturated alcohol of the general formula R--CHâ•?CH(CH 2 ) n+1 OH, in which R is a hydrogen atom or a monovalent hydrocarbon group having 1 to 10 carbon atoms and the subscript n is an integer in the range from 3 to 10, in which an acetate of the formula R--CHâ•?CHCH 2 OCOCH 3 is subjected to a coupling reaction with a Grignard reagent of the formula X 1 Mg(CH 2 ) n OMgX 2 , in which X 1 and X 2 are each a halogen atom, and then the reaction product is hydrolyzed. When the reaction product of the coupling reaction is reacted with acetic anhydride instead of hydrolysis, the corresponding acetate can readily be obtained. These unsaturated alcohols and acetates form a class of important biologically active compounds or intermediates thereof including sex pheromone compounds of insects.