CAS: 198470-85-8; Sodium ((4-(5-Methyl-3-Phenylisoxazol-4-yl)Phenyl)Sulfonyl)(Propionyl)Amide

专利信息

专利号:US-2003157061-A1
优先权日:2001-12-05
标 题 :Combinations of a cyclooxygenase-2 selective inhibitor and a TNFalpha antagonist and therapeutic uses therefor
发明人：BENNETT DENNIS A
权利人:PHARMACIA CORP
摘要:A method for the prevention, treatment, or inhibition of pain, inflammation, or inflammation-related disorder and for the prevention, treatment, or inhibition of a cardiovascular disease or disorder in a subject that is in need of such prevention, treatment or inhibition, involves the administration to the subject of a cyclooxygenase-2 selective inhibitor or prodrug thereof and a TNFα antagonist. A method can also involve the treatment, prevention, or inhibition of cancer in a subject in need of such treatment, prevention, or inhibition, by administering to the subject a cyclooxygenase-2 selective inhibitor or prodrug thereof and a TNFα antagonist which is selected from the group consisting of a compound that affects the synthesis of TNFα, a compound that inhibits the binding of TNFα with a receptor specific for TNFα, and a compound that interferes with intracellular signaling triggered by TNFα binding with a receptor. Compositions, pharmaceutical compositions and kits that can be used with the methods are also described.

专利号:US-8183409-B2
优先权日:2004-05-06
标题:High yield and rapid synthesis methods for producing metallo-organic salts
发明人：CHRISTGAU STEPHAN; ANDERSEN JENS E T
权利人:CHRISTGAU STEPHAN; ANDERSEN JENS E T; OSTEOLOGIX AS
摘要:A new method for preparing salts of metal cations and organic acids, especially divalent salts of alkaline earth metal ions from group II of the periodic system and carboxylic acids. The method comprising the use of a high temperature (about 90° or more) and, optionally. high pressure, in order to obtain a higher yield, purity and faster reaction speed than obtained with known synthesis methods. In particular, the present invention relates to the production of strontium salts of carboxylic acids. Novel strontium salts are also provided by the present method.

专利号:CN-111257441-A
优先权日:2019-12-31
标 题 :A kind of detection method of impurities in parecoxib sodium synthesis process

专利号:CN-105367508-A
优先权日:2015-11-25
标题:A kind of preparation method of parecoxib sodium synthesis process impurity

专利号:CN-105367508-B
优先权日:2015-11-25
标 题 :A kind of preparation method of Parecoxib Sodium synthesis technique impurity

专利号:WO-2024254278-A9
优先权日:2023-06-08
标题 :Ophthalmic films
发明人：BANERJEE AMRITA; MITRAGOTRI SAMIR; LEVINSON DOUGLAS
权利人:FOUNT BIO INC
摘要:The present application describes the synthesis, formulation and uses of systems comprising conjugates or materials prepared therefrom, capable of retaining systems on the ocular surface.