CAS: 10031-82-0; 4-Ethoxybenzaldehyde

该化合物是一种芳香藻,其特征是,在甲苯环相对于甲丁烯功能组(CHO)的准位置,附于苯环的乙氧基组(-OCH2CH3),一种乙氧基苯甲胺,该化合物一般是一种无色的黄色黄色液体,具有甜味,花粉味,在乙醇和乙醚等有机溶剂中,可中度溶解,但由于其水溶性强的乙氧类,该化合物在水溶性中溶性有限.该化合物用于有机合成和香水中芳香成分中,其回活性主要归因于甲丁基苯的功能组,可进行典型的反应,如氧化,减少和凝聚.此外,4-乙氧基苯并丁可因乙氧组的电饱和性替代反应而参与,但由于其水溶性性质,该混合物的溶解性有限.该化合物用于有机合成合成合成和香化成分,在皮肤化合物上可采取安全措施.

结构式图片

相似化合物

23676-08-6 23676-09-7 619-86-3

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

CAS号74-96-4 溴乙烷 | CAS号123-08-0 4-羟基苯甲醛; 对羟基苯甲醛 | CAS号75-03-6 碘乙烷 | CAS号6214-44-4 对乙氧基苄醇 | CAS号64-67-5 硫酸二乙酯 | CAS号64-17-5 乙醇 | CAS号459-57-4 对氟苯甲醛 | CAS号67272-97-3 4-乙氧基-N,N-二乙基苯胺 | CAS号1178964-07-2 2-(4-ethoxyphen... | CAS号108373-05-3 3-溴-4-乙氧基苯甲醛 | CAS号55836-71-0 4-乙氧基苯甲酰胺 | CAS号1504-69-4 4-乙氧基肉桂酸乙酯 | CAS号141701-93-1 1,3-bis(4-ethox... | CAS号14921-71-2 4-[(4-ethoxyphe... | CAS号23491-52-3 赫斯特荧光染料33342 | CAS号2373-79-7 4-乙氧基肉桂酸 | CAS号6653-80-1 1-氯甲基-4-乙氧基苯 | CAS号622-60-6 4-甲基苯乙醚 | CAS号108-88-3 甲苯

合成工艺路线路线简述

    苯乙醚置于盐酸,三氯化铝,氢氰酸体系中,化学反应生成4-乙氧基苯甲醛
    参考文献:Gattermann,Chemische Berichte,1898,Vol. 31,P. 151
    标题:Gattermann,Chemische Berichte,1898,Vol. 31,P. 151

    专利信息


    专利号:US-5861532-A
    优先权日:1997-03-04
    标 题:Solid-phase synthesis of N-alkyl amides
    发明人:BROWN EDWARD G; NUSS JOHN M
    权利人:CHIRON CORP
    摘要:Methods for solid phase synthesis of N-alkyl amides comprise reductive amination of carbonyl compounds using a reducing agent and an amine-containing linker bound to a solid support. The methods afford high yields of linker-bound, monoalkylated amines, and subsequent coupling with acid derivatives provide derivatized N-substituted amides in excellent yields after cleavage from the solid-phase. Compositions useful in solid phase synthesis are also described.

    专利号:US-6133409-A
    优先权日:1996-12-19
    标 题:Process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and αβ-unsaturated carboxylic acid and aldehyde compounds
    发明人:SALVINO JOSEPH M; MORTON GEORGE C; MASON HELEN J; LABAUDINIERE RICHARD F
    权利人:AVENTIS PHARM PROD INC
    摘要:This invention is directed to a process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and alpha , beta -unsaturated carboxylic acid and aldehyde compounds and to polymeric hydroxylamine resin compounds useful therefor.

    专利号:US-6710208-B2
    优先权日:1996-12-19
    标题 :Process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and α,β-unsaturated carboxylic acid and aldehyde compounds
    发明人:SALVINO JOSEPH M; MORTON GEORGE C; MASON HELEN J; LABAUDINIERE RICHARD F
    权利人:AVENTIS PHARMA INC
    摘要:This invention is directed to a process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and α,β-unsaturated carboxylic acid and aldehyde compounds and to polymeric hydroxylamine resin compounds useful therefor.

    专利号:US-11745159-B2
    优先权日:2017-10-20
    标题:Heated nanowells for polynucleotide synthesis
    发明人:MARSH EUGENE P; INDERMUHLE PIERRE F; PECK BILL JAMES
    权利人:TWIST BIOSCIENCE CORP
    摘要:Defined sequence RNA synthesis by 3′→5′ direction is now well established and currently in use for synthesis and development of vast variety of therapeutic grade RNA and Si RNA etc. A number of such synthetic RNA requires a modification or labeling of 3′-end of an oligonucleotide. The synthesis of 3′-end modified RNA requiring lipophilic, long chain ligands or chromophores, using 3′→5′ synthesis methodology is challenging, requires corresponding solid support and generally results in low coupling efficiency and lower purity of the final oligonucleotide in general because of large amount of truncated sequences containing desired hydrophobic modification. We have approached this problem by developing reverse RNA monomer phosphoramidites for RNA synthesis in 5′→3′-direction. They lead to very clean oligonucleotide synthesis allowing for introduction of various modifications at the 3′-end.

    专利号:US-2024051897-A1
    优先权日:2022-07-26
    标题:Synthesis of complex 15n-labeled molecules
    发明人:DORSHEIMER JULIA; ROVIS TOMISLAV
    权利人:UNIV COLUMBIA
    摘要:Methods for conversion of a broad range of amines to their 15N isotopic counterparts and the compounds produced thereby.

    专利号:US-5175302-A
    优先权日:1987-07-13
    标 题 :Nucleophilic fluoroalkylation of aldehydes
    发明人:STAHLY G PATRICK
    权利人:ETHYL CORP
    摘要:Aryl difluoromethyl sulfone adds to aldehydes under phase transfer conditions to give novel substituted alcohols of the general formula n n RCH(OH)CF.sub.2 SO.sub.2 Ar (I) n n wherein R is an aryl, cycloaliphatic, sec- or tert-aliphatic, or heterocyclic group and Ar is an aryl group. The substituted alcohols of formula I are of particular utility as intermediates in the synthesis of a variety of useful end products. For example, the products of formula I may be utilized in desulfonylation reactions, oxidation reactions and fluorination reactions.
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    ✅ COA系统入驻 | 共享模式

    主要参考文献

    参考标题:Synthesis Of Novel 5,6-Dehydrokawain Analogs As Osteogenic Inducers And Their Action Mechanisms
    作者:Momochika Kumagai,Keisuke Nishikawa,Takashi Mishima,Izumi Yoshida,Masahiro Ide,Keiko Koizumi,Munetomo Nakamura,Yoshiki Morimoto |发布日期:2017.6
    摘要:Protein (Bmp) And Activation Of P38 Mapk Signaling Pathways. Compounds 14 And 21 Also Inhibited Rankl-Induced Osteoclast Differentiation Of Raw264 Cells. These Results Indicated That Novel 5,6-Dehydrokawain Analogs Not Only Increase Osteogenic Activity But Also Inhibit Osteoclast Differentiation, And Could Be Potential Lead Compounds For The Development Of Anti-Osteoporosis Agents.

    合成参考文献


    摘要:Joule, J. A., Science of Synthesis Knowledge Updates, (2018) 2, 339.
    摘要:Dong, X.; Liu , H., Science of Synthesis Knowledge Updates, (2019) 3, .
    摘要:Huang, Y.; Dömling, A., Science of Synthesis: Multicomponent Reactions, (2013) 1, 261.
    摘要:S109 | PARCEDC | List of 7074 potential endocrine disrupting compounds (EDCs) by PARC T4.2 | DOI:10.5281/zenodo.10944198
    参考文献:10.1107/s1600536810048026
    摘要:Sarveswari S, Vijayakumar V, Prasath R, Narasimhamurthy T, Tiekink ER. (2E)-3-(4-Eth-oxy-phen-yl)-1-(2-methyl-4-phenyl-quinolin-3-yl)prop-2-en-1-one monohydrate. Acta Crystallogr Sect E Struct Rep Online. 2010 Nov 24;66(Pt 12):o3284.
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