专利号:US-6531470-B1 优先权日:1998-01-23 标题:Oxazolidinone combinatorial libraries, compositions and methods of preparation 发明人:GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V; NI ZHI-JIE; GORDON ERIC 权利人:UPJOHN CO 摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.
专利号:US-6562844-B2 优先权日:1998-01-23 标 题:Oxazolidinone combinatorial libraries, compositions and methods of preparation 发明人:GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V; NI ZHI-JIE; GORDON ERIC 权利人:UPJOHN CO 摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.
专利号:US-7002020-B1 优先权日:1998-01-23 标题:Oxazolidinone combinatorial libraries, compositions and methods of preparation 发明人:GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V 权利人:UPJOHN CO 摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.
专利号:CN-110256221-B 优先权日:2019-05-13 标题:Synthesis method of 2-alkylanthraquinone
专利号:CN-116730819-A 优先权日:2023-02-02 标题:A green synthesis method of ultrapure anthraquinone and 2-alkylanthraquinone
参考标题:Continuous-Flow Retro-Diels-Alder Reaction: A Process Window For Designing Heterocyclic Scaffolds 作者:Imane Nekkaa,Márta Palkó,István M. Mándity,Ferenc Miklós,Ferenc Fülöp |发布日期:2018.8.31 摘要:An Approach Based On A Highly Controlled Continuous‐flow (Cf) Retro‐diels-Alder Reaction Was Developed For The Synthesis Of New Compounds. Using This Approach, We Were Able To Rapidly Screen Reaction Conditions To Obtain The Desired Pyrimidinone Moieties In Short Reaction Times And High Yields. We Also Present An Alternative Route For The Synthesis Of Intermediates By Cf Cyclization.
合成参考文献
摘要:L. G. Bray, J. F. J. Dippy and S. R. C. Hughes, J. Chem. Soc. 1957, 265.