其它别名Acetic Acid, 2-[2-[4-(Diphenylmethyl)-1-Piperazinyl]Ethoxy]-; Deschloro Cetirizine; Levocetirizine Impurity 20; Deschloro Cetirizine Hcl; Deschloro Cetirizine Dihcl; Usp Deschlorocetirizine; Cetirizine Ep Impurity Fq: What Is Cetirizine Ep Impurity F Q: What Is The Cas Number Of Cetirizine Ep Impurity F Q: What Is The Storage Condition Of Cetirizine Ep Impurity F Q: What Are The Applications Of Cetirizine Ep Impurity F; 2-(2-(4-Benzhydrylpiperazin-1-yl)Ethoxy)Acetic Acid (Cetirizine Impurity)
专利号:US-8350031-B2 优先权日:2008-06-02 标 题:Processes for the synthesis of levocetirizine and intermediates for use therein 发明人:RAO DHARMARAJ RAMACHANDRA; KANKAN RAJENDRA NARAYANRAO; GHAGARE MARUTI; CHIKHALIKAR SANDIP VASANT 权利人:CIPLA LTD; RAO DHARMARAJ RAMACHANDRA; KANKAN RAJENDRA NARAYANRAO; GHAGARE MARUTI; CHIKHALIKAR SANDIP VASANT 摘要:The present invention provides a compound of formula (IV) n nwherein R is Cl, Br, NO 2 , OH or OR′, and R′ is alkyl, and its use in the synthesis of levocetirizine, including its use in the synthesis of (−)-1-[(4-chlorophenyl)-phenylmethyl]piperazine, an intermediate useful in the synthesis of levocetirizine. The present invention also provides compounds (II) and (III) which are useful in the synthesis of compound (IV).
专利号:US-2011184174-A1 优先权日:2008-06-02 标题 :Processes for the Synthesis of Levocetirizine and Intermediates for Use Therein
参考标题:Processes For The Synthesis Of Levocetirizine And Intermediates For Use Therein 摘要:The Present Invention Provides A Compound Of Formula (Iv) Wherein R Is Cl, Br, No 2 , Oh Or Or′, And R′ Is Alkyl, And Its Use In The Synthesis Of Levocetirizine, Including Its Use In The Synthesis Of (−)-1-[(4-Chlorophenyl)-Phenylmethyl]Piperazine, An Intermediate Useful In The Synthesis Of Levocetirizine. The Present Invention Also Provides Compounds (II) And (III) Which Are Useful In The Synthesis Of Compound (Iv).