CAS: 765-09-3; 1-Bromotridecane

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CAS号544-63-8 肉豆蔻酸 | CAS号112-70-9 十三醇 | CAS号112-44-7 十一醛 | CAS号671787-02-3 ethyl tridec-2-... | CAS号28267-29-0 十三酸乙酯 | CAS号2437-56-1 1-十三烯 | CAS号68975-76-8 1,1'-[methylene... | CAS号112-64-1 肉豆蔻酰氯 | CAS号10035-10-6 氢溴酸 | CAS号7789-69-7 五溴化磷 | CAS号19484-26-5 1-十三烷硫醇 | CAS号19308-06-6 °Ctadec-4-enoic acid | CAS号198011-30-2 2-°Ctadec-4-yno... | CAS号554-62-1 糖脂 | CAS号2834-03-9 2-Hexadecynoate | CAS号2825-68-5 Hexadecenoic ac... | CAS号2380-20-3 5-氧代十八烷酸甲酯 | CAS号123-78-4 D-鞘氨醇 | CAS号18787-63-8 2-十六烷酮 | CAS号27519-02-4 顺-9-二十三烯

十三烷醇置于四丁基溴化铵,氢溴酸体系中,用70.1 %的收率获得产物1-溴十三烷
参考文献:使用基于季戊四醇的单组分可电离两亲性 Janus 树枝状聚合物将 Mrna 靶向且均匀分布地递送至器官
标题:使用基于季戊四醇的单组分可电离两亲性 Janus 树枝状聚合物将 Mrna 靶向且均匀分布地递送至器官
摘要:用病毒和合成载体输送核酸开创了遗传纳米医学的先河.四组分脂质纳米粒子 (Lnp) 由可电离脂质,磷脂,胆固醇和 Peg 缀合脂质组成,通过微流体或 T 管组装,是用于递送 Mrna 的基准合成载体.我们开发了一种用于 Mrna 的单组分多功能序列定义电离两亲性 Janus Dendrimer (Iajd) 递送系统,以补充 Lnp.iajd 由多功能亲水性低代树突或与疏水性树突缀合的小树突组成.他们的灵感来自于两亲性 Janus 树枝状聚合物和糖树枝状聚合物.iajd 通过简单地注射到醋酸盐缓冲液中,而不是通过 Lnp 所需的复杂技术,与 Mrna 共同组装成可预测大小的囊泡,称为树状聚合物纳米颗粒 (Dnp).通过简单注射组装 Dnp 以及 Iajd 亲水和疏水模块中的序列设计,可以快速筛选以实现发现.当 Iajd 的分支点由通过季戊四醇 (Pe) 连接的对称和非对称取代的植物酚酸构建时
DOI:10.1021/jacs.3C07337

专利信息

专利号:US-5962515-A
优先权日:1997-05-29
标题 :Process for isolation and synthesis of 1-(3,4 methylenedioxy-phenyl)-1E-tetradecene and its analogues and their activities against tumors and infections
发明人：UPADHYAY SHAKTI N; VISHWAKARMA RAM A; GHOSAL SABARI; SHUKLA SUPRIYA; BOSE CHANDA; KAMRA ANITA
权利人:NAT INST IMMUNOLOGY
摘要:Process for isolation of 1-(3,4-methylenedioxy-phenyl)-1E-tetradecene from Piper longum. Processes for synthesis of 1-(3,4-methylenedioxy-phenyl)-1E-tetradecene; its stereoisomers and analogues are disclosed. The compounds isolated and synthesized according to this invention have immunomodulatory properties and can be used to treat tumors and infections.

专利号:US-9006472-B2
优先权日:2011-11-17
标 题 :Methods for the synthesis of 13C labeled plasmalogen
发明人：KHAN M AMIN; WOOD PAUL L; GOODENOWE DAYAN
权利人:PHENOMENOME DISCOVERIES INC
摘要:A method for preparing 13 C labeled plasmalogens as represented by Formula B: n n n n n n n n n n The method involves producing a 13 C labeled cyclic plasmalogen precursor of Formula A: n nand conversion of the precursor to a plasmalogen of Formula B.

专利号:US-9169280-B2
优先权日:2011-11-17
标 题:Methods for the synthesis of plasmalogens and plasmalogen derivatives, and therapeutic uses thereof
发明人：KHAN M AMIN; WOOD PAUL L; GOODENOWE DAYAN
权利人:PHENOMENOME DISCOVERIES INC
摘要:A method for preparing plasmalogens and derivatives thereof represented by Formula B, wherein R1 and R2 are similar or different, derived from fatty acids; R3 is selected from hydrogen and small alkyl groups. The synthetic route involves production of novel cyclic plasmalogen precursors of Formula A and their conversion to plasmalogens and plasmalogen derivatives of Formula B. Also disclosed is the therapeutic use of plasmalogens and derivatives thereof as produced by the synthetic route of the present invention.

专利号:US-2014323749-A1
优先权日:2011-11-17
标题:Methods for the synthesis of 13c labeled plasmalogen

专利号:WO-2013071412-A1
优先权日:2011-11-17
标 题:Methods for the synthesis of 13c labeled plasmalogen

专利号:GB-2450682-A
优先权日:2007-06-26
标题 :Use of benzyl protection in the synthesis of 5-n-alkylresorcinols