CAS: 6310-09-4; 2-Acetyl-5-Chlorothiophene

上下游产品

CAS号96-43-5 2-氯噻吩 | CAS号108-24-7 乙酸酐 | CAS号75-36-5 乙酰氯 | CAS号88-15-3 2-乙酰基噻吩 | CAS号1956-45-2 1-(噻吩-2-基)乙酮肟 | CAS号114773-97-6 2-乙酰基噻吩邻甲基肟 | CAS号42518-98-9 5-氯-2-酰氯噻吩 | CAS号230972-02-8 1-[5-(4-吗啉)-2-噻吩]乙酮 | CAS号188937-11-3 ethyl 3-(5-chlo... | CAS号88653-55-8 2-乙酰-5-氰基噻吩 | CAS号30955-94-3 2-乙酰基-5-碘噻吩 | CAS号22353-82-8 5-氯噻吩-2-甲酰胺 | CAS号24065-33-6 2-氯噻吩-5-甲酸 | CAS号88-15-3 2-乙酰基噻吩 | CAS号18494-73-0 5,5-二乙酰基-2,2-联噻吩 | CAS号57731-17-6 2-溴-1-(5-氯噻吩-2-基)乙酮

5-Chloro-2-(α-Methoxyimino)Ethylthiophene置于盐酸体系中,化学反应 8.0H,以96%的收率获得产物2-乙酰基-5-氯噻酚
参考文献:Facile Synthesis Of 5-Substituted 2-Acetylthiophenes
标题:Facile Synthesis Of 5-Substituted 2-Acetylthiophenes
摘要:5-取代的2-(α-烷氧亚胺)乙基噻吩4-8是通过2-(α-烷氧亚胺)乙基噻吩3与电亲试剂反应获得的.噻吩4-8的水解分别产生5-取代的2-乙酰噻吩9-13.化合物3可以通过2-乙酰噻吩(1)与o-烷基羟胺的反应,或通过对1的氧化后进行o-烷基化来轻松获得.
DOI:10.1055/s-1992-26245

专利信息

专利号:WO-2013046211-A1
优先权日:2011-09-27
标 题 :Processes for the preparation of 5-chloro-n-({(5s)-2-oxo-3-[4-(3-oxo-4-morpholinyl) phenyl]-1,3-oxazolidin-5-yl}methyl)-2-thiophene-carboxamide and intermediates thereof
发明人：MOHAN RAO DODDA; KRISHNA REDDY PINGILI; VENKAT REDDY BUTHUKURI
权利人:SYMED LABS LTD; MOHAN RAO DODDA; KRISHNA REDDY PINGILI; VENKAT REDDY BUTHUKURI
摘要:TThe present invention provides processes for the preparation of 5-chloro-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-1,3-oxazolidin-5-yl}methyl)-2-thiophene-carboxamide (I) and intermediates thereof. Also provides novel intermediates and their use in the synthesis of oxazolidine derivatives.

专利号:WO-2013027225-A1
优先权日:2011-08-19
标 题:Processes for the preparation of 4-{4-[5(s)-(aminomethyl)-2-oxo-1,3-oxazolidin-3-yl]phenyl} morpholin-3-one
发明人：MOHAN RAO DODDA; KRISHNA REDDY PINGILI; VENKAT REDDY BUTHUKURI
权利人:SYMED LABS LTD; MOHAN RAO DODDA; KRISHNA REDDY PINGILI; VENKAT REDDY BUTHUKURI
摘要:The present invention provides simple, eco-friendly, cost-effective, reproducible, robust and industrial processes for the preparation of intermediate compound 4-{4-[5(S)-(aminomethyl)-2-oxo-1,3-oxazolidin-3-yl]phenyl}morpholin-3-one (II). The present invention also provides novel intermediates and their use in the synthesis of morpholinone oxazolidine derivatives.

专利号:CN-108840854-B
优先权日:2018-09-18
标 题 :A kind of method for one-pot synthesis of 5-chlorothiophene-2-carboxylic acid

专利号:CN-117486872-A
优先权日:2023-11-15
标 题 :Mechanical ball milling synthesis method of aminothiazole compound