📜Alkaline Earth Salt Of/the/ Methylsulfuric Acid置于盐酸体系中,化学反应生成 S-苄基异硫脲盐酸盐 参考文献:Chabrier,Bulletin De La Societe Chimique De France,1947,P. 797,805 标题:Chabrier,Bulletin De La Societe Chimique De France,1947,P. 797,805
专利号:US-12415828-B2 优先权日:2014-08-22 标题:Modified oligonucleotides and methods for their synthesis 发明人:STETSENKO DMITRY; KUPRYUSHKIN MAXIM; PYSHNYI DMITRII 权利人:NOOGEN LLC 摘要:Modified oligonucleotides that contain one or more of the phosphate groups substituted at phosphorus and methods for their synthesis are disclosed.
专利号:US-7732436-B2 优先权日:2003-05-19 标 题 :Preparation of hymenialdisine derivatives and use thereof 发明人:TEPE JETZE J 权利人:UNIV MICHIGAN STATE 摘要:The synthesis and biological activity of indoloazepines and acid amine salts thereof which are structurally related to naturally-occurring hymenialdisine is disclosed. Naturally-occurring hymenialdisine obtained from the sponge is a potent inhibitor of production of cytokines interleukin-2 (IL-2) and tumor necrosis factor-α (TNF-α). The chemically-synthesized indoloazepines of the invention also inhibit production of IL-2 and TNF-α. The indoloazepines are useful for treating inflammatory diseases, particularly diseases associated with kinases NF-κB or GSK-3β activation or NF-κB activated gene expression products. The indoloazepines are useful for the treatment of cancer by the inhibition of kinases CHK1 and CHK2.
专利号:DE-2928136-A1 优先权日:1979-07-12 标 题:PHOSPHOROUS AZO COMPOUNDS AND THE PRODUCTION AND USE THEREOF AS PEST CONTROL, LIGHT-SENSITIVE MATERIALS AND AS SUBSTANCES FOR THE SYNTHESIS OF PYRAZOLONES
专利号:EP-0022512-A1 优先权日:1979-07-12 标题:Azo compounds containing phosphorus, their preparation, and their use as pesticides, as light sensitive materials and as starting materials for the synthesis of pyrazolones
专利号:CN-119192087-A 优先权日:2024-08-27 标 题 :Chemical synthesis method of ergothioneine
[参考文献]: Kenji Matsuno, Et Al. S-Benzylisothiourea Derivatives As Small-Molecule Inhibitors Of Indoleamine-2,3-Dioxygenase. Bioorg Med Chem Lett. 2010 Sep 1;20(17):5126-9.