CAS: 4132-48-3; 4-Isopropylanisole

该化合物是一种合成芳香化合物,其特点是异丙基代代苯乙醇结构,由于其稳定的芳香特征,通常用作有机合成和芳香应用中的中间体;该化合物在有机溶剂中表现出有利的溶解性,便于其在各种化学工艺中使用;其独特的气味特性使它适合融入香水和香味配方;该异丙基混合物组增加了其挥发性,并与其他芳香成分相容.从工业角度讲,它因其在电子生物替代反应中具有一贯的纯度和再活动性而具有价值.建议适当处理和储存以保持其化学完整性.

结构式图片

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

CAS号104-92-7 对溴苯甲醚 | CAS号1888-75-1 异丙基锂 | CAS号50625-30-4 trifluoro(4-met... | CAS号75-26-3 2-溴丙烷 | CAS号77047-87-1 2-丙基溴化锌 | CAS号1712-69-2 1-甲氧基-4-(1-丙烯-2-基)苯 | CAS号99-89-8 4-异丙基苯酚 | CAS号74-88-4 碘甲烷 | CAS号78176-20-2 1-methoxy-4-(2-... | CAS号5720-07-0 4-甲氧基苯硼酸 | CAS号5432-85-9 4-异丙基环己酮 | CAS号99-89-8 4-异丙基苯酚 | CAS号32445-98-0 2,3-bis(4-metho... | CAS号100-09-4 对甲氧基苯甲酸 | CAS号100-06-1 对甲氧基苯乙酮 | CAS号18428-19-8 1-(2-hydroperox... | CAS号7428-99-1 2-(4-甲氧基苯基)丙-2-醇 | CAS号150-76-5 4-甲氧基苯酚(MEHQ) | CAS号100-17-4 4-硝基苯甲醚 | CAS号1576-10-9 2-硝基-4-乙基苯酚

合成工艺路线路线简述

    📜1-异丙烯基-4-甲氧基苯置于[fe3(Hmds)4]Fe(η6-Toluene),氢气体系中,20.0 °C,190.0 Kpa 条件下,反应 3.0H,以100%的收率获得产物4-异丙基苯甲醚
    参考文献:可溶性铁纳米团簇催化剂的烯烃加氢
    标题:可溶性铁纳米团簇催化剂的烯烃加氢
    摘要:贵金属技术的替代以及利用地球上丰富的金属实现新的反应性是可持续合成的核心.迄今为止,烯烃加氢最有效地是通过贵金属催化剂进行的.本研究报道了一种铁催化的三取代和四取代烯烃氢化方案,该方案在温和条件(1-4 Bar H 2,20 oc)下具有前所未有的活性和范围.通过分离充当催化剂库和颗粒生长的可溶种子的新型铁纳米簇结构,记录了均相和非均相铁催化界面的指导性快照.
    DOI:10.1002/anie.201612548

    海关参考信息

    专利信息


    专利号:US-8293930-B1
    优先权日:2004-06-25
    标题 :One pot synthesis of taxane derivatives and their conversion to paclitaxel and docetaxel
    发明人:NAIDU RAGINA
    权利人:NAIDU RAGINA; CHATHAM BIOTEC LTD
    摘要:A process is provided for the semi-synthesis of taxane intermediates useful in the preparation of paclitaxel and docetaxel, in particular, the semi-synthesis of protected taxane intermediate in a one pot reaction of protecting the C-7 and C-10 positions and attaching a side chain at the C-13 position and subsequently deprotecting the group to form paclitaxel or docetaxel, and taxane intermediates.

    专利号:US-7893283-B2
    优先权日:2004-06-04
    标题:Semi-synthesis of taxane intermediates and their conversion to paclitaxel and docetaxel
    发明人:NAIDU RAGINA
    权利人:CHATHAM BIOTEC LTD
    摘要:A process is provided for the semi-synthesis of taxane intermediates useful in the preparation of paclitaxel and docetaxel, in particular, the semi-synthesis of protected taxane intermediates.

    专利号:US-7202370-B2
    优先权日:2003-10-27
    标 题 :Semi-synthesis of taxane intermediates from 9-dihydro-13-acetylbaccatin III
    发明人:NAIDU RAGINA
    权利人:CONOR MEDSYSTEMS INC
    摘要:A method is provided for the semi-synthesis of taxane intermediates useful in the preparation of paclitaxel and docetaxel from 9-dihydro-13-acetylbaccatin III. The preparation of a suitably protected baccatin III backbone from 9-dihydro-13-acetylbaccatin III, and the insertion of the phenylisoserine side chain onto the protected baccatin III from 9-dihydro-13-acetylbaccatin III to form the taxane derivatives, paclitaxel and docetaxel is disclosed.

    专利号:US-2005192445-A1
    优先权日:2004-03-01
    标题:Semi-synthesis of taxane intermediates and aziridine analogues and their conversion to paclitaxel and docetaxel
    发明人:NAIDU RAGINA
    权利人:PHYTOGEN LIFE SCIENCES INC
    摘要:A process is provided for the semi-synthesis of taxane intermediates and aziridine analogues of cephalomannne and baccatin III intermediates, and the conversion of such intermediates and analogues to paclitaxel and docetaxel.

    专利号:US-7358382-B2
    优先权日:2001-08-03
    标 题 :Protected 3,5-dihydroxy-2,2-dimethyl-valeronitriles for the synthesis of epothilones and epothilone derivatives and process for the production
    发明人:WESTERMANN JURGEN; PLATZEK JOHANNES; PETROV ORLIN
    权利人:BAYER SCHERING PHARMA AG
    摘要:The invention relates to 3,5-dihydroxy-2,2-dimethyl-valeronitriles for the synthesis of epothilones and epothilone derivatives and process for the production of these new intermediate products in the synthesis and the use for the production of epothilones or epothilone derivatives.

    专利号:US-8618281-B2
    优先权日:2006-01-03
    标 题 :Geometric synthesis of porphyrin rods
    发明人:LINDSEY JONATHAN S; YU LIANHE; THAMYONGKIT PATCHANITA; BHISE ANIL D
    权利人:LINDSEY JONATHAN S; YU LIANHE; THAMYONGKIT PATCHANITA; BHISE ANIL D; UNIV NORTH CAROLINA STATE
    摘要:A method of making a compound of Formula I′ n ncomprises reacting a compound of the formula DLCHO, with a compound of the formulan n nto produce the compound of Formula I′. Methods of using the compounds are also described, particularly as intermediates for the synthesis of porphyrin rods, which porphyrin rods are in turn useful for (among other things) the production of molecular memory devices.

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:Drabowicz, J.; Krasowska, D.; Wicha, J., Science of Synthesis, (2009) 48, 258.
    摘要:Li, L.; Biscoe, M. R., Science of Synthesis: Cross Coupling and Heck-Type Reactions, (2012) 1, 828.
    摘要:Li, L.; Biscoe, M. R., Science of Synthesis: Cross Coupling and Heck-Type Reactions, (2012) 1, 826.
    摘要:Hou, Z.-W.; Xu, H.-C., Science of Synthesis: Special Topics, (2021) 1, 198.
    摘要:Mateos-Gil, J.; Fa, Science of Synthesis: Knowledge Updates, (2024) 1, 168.
    📝 需求与反馈
    尽可能描述清楚需求与问题信息
    ×

    通知