CAS: 2107-78-0; 7-Hydroxy-3,4-Dimethyl-2H-Chromen-2-One

该化合物是一个由苯乙烯环和丙烯环组成的引信环系统,氢氧基(OH)和甲基(-CH)组的存在有助于其化学反应和溶解性,其典型特征是黄色至橙色,在菜类中很常见,并可能由于存在可以捐赠电子的氢氧基组而表现出抗氧化特性,该化合物经常因其潜在的生物活动而进行研究,包括抗炎,抗微生物和抗癌效应,其在有机溶剂中的溶解性和水溶解性有限,会影响其在各个领域的应用,包括医药和食品科学的应用.此外,其稳定性可能受到光和pH等环境因素的影响,而光和pH等环境因素对其储存和制剂的使用非常重要.

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CAS号609-14-3 2-甲基乙酰乙酸乙酯 | CAS号108-46-3 间苯二酚 | CAS号108171-18-2 7-hydroxy-3,4-d... | CAS号17094-21-2 2-甲基-3-氧代丁酸甲酯 | CAS号2150-47-2 2,4-二羟基苯甲酸甲酯 | CAS号5852-10-8 7-羟基-4-甲基香豆素-3-乙酸 | CAS号829-20-9 2,4-二甲氧基苯乙酮 | CAS号314044-86-5 7-hydroxy-3,4-d... | CAS号35679-93-7 2-[(3,4-dimethy... | CAS号156006-10-9 3,4-dimethyl-7-... | CAS号91406-11-0 乙磺普隆 | CAS号64309-70-2 (3,4-dimethyl-2... | CAS号54917-82-7 1-(2,4-dihydrox...

合成工艺路线路线简述

    📜7-羟基-4-甲基-3-香豆素乙酸置于喹啉,铜体系中,化学反应生成二甲基伞形酮
    参考文献:Shah; Shah,Journal Of The Indian Chemical Society,1942,Vol. 19,P. 481,483
    标题:Shah; Shah,Journal Of The Indian Chemical Society,1942,Vol. 19,P. 481,483

    海关参考信息

    专利信息


    专利号:US-7041812-B2
    优先权日:2001-08-29
    标题 :Labeled nucleoside polyphosphates
    发明人：KUMAR SHIV; SOOD ANUP
    权利人:AMERSHAM BIOSCIENCES CORP
    摘要:The present invention describes new compositions of matter in the form of labeled nucleoside polyphosphates with four or more phosphates. In addition compositions of nucleoside polyphosphates with four or more phosphates that are substrates for nucleic acid polymerases with enhanced substrate properties and methods of using these nucleoside polyphosphates for nucleic acid detection, characterization and quantification are described. The compositions provided by this invention include nucleoside polyphosphate, dideoxynucleoside polyphosphate, or deoxynucleoside polyphosphate analogues which have colorimetric, chemiluminescent, or fluorescent moieties, mass tags or an electrochemical tags attached to the terminal-phosphate. When a nucleic acid polymerase uses this analogue as a substrate, an enzyme-activatable label would be present on the inorganic polyphosphate by-product of phosphoryl transfer. Removal of the polyphosphate product of phosphoryl transfer via phosphate or polyphosphate transferring enzyme leads to a detectable change in the label attached thereon. When the polymerase assay is performed in the presence of a phosphatase, there is provided a convenient method for real-time monitoring of DNA or RNA synthesis and detection of a target nucleic acid.

    专利号:US-7563574-B2
    优先权日:2006-03-31
    标题:Methods, systems and compositions for monitoring enzyme activity and applications thereof
    发明人：KORLACH JONAS; TURNER STEPHEN
    权利人:PACIFIC BIOSCIENCES CALIFORNIA
    摘要:Methods of monitoring enzyme mediated reactions, and particularly nucleic acid synthesis reactions such as pyrosequencing methods that employ enzymatic reporter systems. The methods and systems provide elevated signal levels as compared to conventional pyrosequencing processes, and/or mediate de-phasing of sequencing analyses employing pyrosequencing or other “sequencing by synthesisâ€? methods.

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    主要参考文献

    参考标题:Synthesis Of Dipeptide Derivatives Of 3,4-Substituted 7-Hydroxycoumarins
    作者:S. V. Shilin,M. M. Garazd,V. P. Khilya |发布日期:2008.5
    摘要:Coumarins Modified With Dipeptides Were Prepared By Condensation Of N-Hydroxysuccinimide Esters Of 2-(3,4,8-Substituted-2-Oxo-2H-7-Chromenyloxy)-And 2-(3,4-Substituted-7-Methyl-2-Oxo-2H-5-Chromenyloxy)Acetic And-Propionic Acids With Amino Acids And Dipeptides.

    合成参考文献


    摘要:Cheng, B.; Wang, T., Science of Synthesis Knowledge Updates, (2020) 3, 177.
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