CAS: 20398-06-5; Thallium (I) Ethoxide

上下游产品

ethanol sodium ethanolate thallium(I) methoxide potassium ethoxidethallium(I) benzyl oxide thallous phenoxide H-(2endoO,5'rC1)-spiro[bicyclo[2.2.1]heptane-2,5'-oxazole]4'ξ-ethoxy-4'H-(2endoO,5'rC1)-spiro[bicyclo[2.2.1]heptane-2,5'-oxazole] methyl 4-ethoxybenzoate

专利信息

专利号:US-5484867-A
优先权日:1993-08-12
标题:Process for preparation of polyhedral oligomeric silsesquioxanes and systhesis of polymers containing polyhedral oligomeric silsesqioxane group segments
发明人：LICHTENHAN JOSEPH D; GILMAN JEFFREY W; FEHER FRANK J
权利人:UNIV DAYTON; UNIV CALIFORNIA; US ARMY
摘要:A process for preparation of reactive polyhedral oligomeric silsesquioxanes and the subsequent synthesis of polysilsesquioxanes which produce high yield, tractable polymers containing silsesquioxane segments is provided. A trifunctional polyhedral oligomeric silsesquioxane of the formula Si 7 R 7 O 9 (OA) 3 is corner capped by reacting it with a compound of the formula M-Z to form a polyhedral oligomeric silsesquioxane which can be reacted in various ways with oligomers, polymers, catalysts, or co-monomers to form polyhedral silsesquioxane polymers containing silsesquioxanes as pendant, block, or end group segments. The resulting polymers are essentially free of impurities and have controllable properties through the proper selection of the synthesis process and starting materials.

专利号:US-4158005-A
优先权日:1975-02-10
标题:Intermediates useful in the synthesis of optically active m-acyloxy-α-[(methylamino)methyl]benzyl alcohols
发明人：BODOR NICOLAE S; YUAN SUN-SHINE
权利人:INTERX RESEARCH CORP
摘要:Optically and therapeutically active compounds of the formula: ##STR1## wherein R represents a member selected from the group consisting of a straight or branched alkyl group of from one to twenty carbon atoms (C 1 -C 5 being preferred), an ethoxycarbonyl group, a benzyloxycarbonyl group, a phenyl group, an ##STR2## WHEREIN R is as defined above and R 3 is a member selected from the group consisting of a hydrogen atom, a methyl group and a phenyl group, and a 2-, 3-, or 4-pyridyl group, or the HX salts thereof, wherein X represents a pharmaceutically acceptable acid addition salt anion, are prepared optically active m-hydroxy-α-[methylamino)methyl]benzyl alcohol (phenylephrine). n The compounds prepared by the process of this invention find therapeutic application to warm-blooded animals (e.g., humans) in the management of asthma, nasal congestion and as decongestants, vasoconstrictors, mydriatic agents, and anti-glaucomatous agents in the practice of ophthalmology. n Upon administration, these compounds will enzymatically 'cleave,' thus releasing optically active phenylephrine (m-hydroxy-α-[(methylamino)methyl]benzyl alcohol, the therapeutically active moiety thereof.

专利号:US-4028368-A
优先权日:1975-02-10
标 题:Novel intermediates useful in the synthesis of optically active m-acyloxy-α-[(methylamino)methyl]benzyl alcohols
发明人：BODOR NICOLAE S; YUAN SUN-SHINE
权利人:INTERX RESEARCH CORP
摘要:Optically and therapeutically active compounds of the formula: ##STR1## wherein R represents a member selected from the group consisting of a straight or branched alkyl group of from one to twenty carbon atoms (C 1 -C 5 being preferred), an ethoxycarbonyl group, a benzyloxycarbonyl group, a phenyl group, an ##STR2## group, wherein R is as defined above and R 3 is a member selected from the group consisting of a hydrogen atom, a methyl group and a phenyl group, and a 2-, 3-, or 4-pyridyl group, or the HX salts thereof, wherein X represents a pharmaceutically acceptable acid addition salt anion, are prepared using optically active m-hydroxy-α-[(methylamino)methyl]benzyl alcohol (phenylephrine).

专利号:US-4174450-A
优先权日:1975-02-10
标 题:Intermediates useful in the preparation of optically and therapeutically active-m-acyloxy-(methyl-amino) methyl benzyl alcohols
发明人：BODOR NICOLAE S; YUAN SUN-SHINE
权利人:INTERX RESEARCH CORP
摘要:This invention deals with chemical intermediates having the formula ##STR1## wherein R 1 and R 2 together with the carbon atom to which they are attached form a single hetero atom member selected from the group consisting of a five-to seven-membered heterocycle containing one hetero-N-atom and a N-substituted five-to seven-membered heterocycle containing an hetero-N-atom whose substituent is C 1 -C 2 alkyl. These compounds are useful in the synthesis of compounds having a variety of uses as pharmaceuticals.

专利号:US-5756774-A
优先权日:1997-02-04
标 题:Synthesis of myo-inositol phosphates
发明人：BITTMAN ROBERT; LEUNG LAWRENCE
摘要:Provided herein are novel syntheses of the phosphate-based inositol derivatives 1-O- (+)-menthoxycarbonyl!-6-O-benzyl-2,3:4,5-di-O-isopropylidene-myo-inositol (D4P), D-myo-inositol 1,4,5-trisphosphate (D-IP 3 ), 6-O-benzyl-2,3:4,5-di-O-isopropylidene-myo-inositol H-phosphonate ((-)-3-HP) and L-myo-inositol 1,4,5-trisphosphate (L-IP 3 ). These syntheses employ fewer column chromatography steps for the isolation of intermediates than do prior art syntheses, and hence, are more convenient, economical and efficient than are the previously known synthetic methods.

专利号:US-2004053999-A1
优先权日:1997-09-17
标题 :Novel compounds and methods for synthesis and therapy
发明人：BISCHOFBERGER NORBERT W; DAHL TERRENCE C; HITCHCOCK MICHAEL J M; KIM CHOUNG U; LEW WILLARD; LIU HONGTAO; MILLS ROGER G; WILLIAMS MATTHEW A
摘要:Novel compounds are described. The compounds generally comprise an acidic group, a basic group, a substituted amino or N-acyl and a group having an optionally hydroxylated alkane moiety. Pharmaceutical compositions comprising the inhibitors of the invention are also described. Methods of inhibiting neuraminidase in samples suspected of containing neuraminidase are also described. Antigenic materials, polymers, antibodies, conjugates of the compounds of the invention with labels, and assay methods for detecting neuraminidase activity are also described.