CAS: 190011-87-1; 3-Chloro-2,6-Difluorobenzaldehyde

上下游产品

1-chloro-2,4-difluorobenzene 4-morpholinecarboxaldehyde n-butyllithium (3-chloro-2,6-difluoro-phenyl)-methanol 2-(3-chloro-2,6-difluoro-phenyl)-imidazole 3-chloro-2,6-difluorobenzonitrile (Z)-1-(1H-benzoimidazol-5-yl)-5-(3-chloro-2,6-difluoro-phenyl)-4-cyclohexylimino-imidazolidin-2-one (Z)-1-(3H-benzoimidazol-5-yl)-5-(3-chloro-2,6-difluoro-phenyl)-4-(1,2,2-trimethyl-propylimino)-imidazolidin-2-one

2,4-二氟氯苯置于lithium Diisopropyl Amide体系中,用 Dmf (N,N-Dimethyl-Formamide) 用作溶剂,化学反应生成3-氯-2,6-二氟苯甲醛
参考文献:2″-Deoxy Hygromycin Derivatives
标题:2″-Deoxy Hygromycin Derivatives
摘要:这项发明涉及公式化合物及其药学上可接受的盐,前药和溶剂化合物,其中r1和r2如本文所定义.公式1的化合物是抗菌和抗原虫剂,可用于治疗各种细菌和原虫感染以及与此类感染相关的疾病.该发明还涉及含有公式1化合物的药物组合物以及通过给予公式1化合物治疗细菌和原虫感染的方法.

专利信息

专利号:EP-3070087-B1
优先权日:2011-08-05
标题 :Intermediates for the synthesis of cyclic p1 linkers as factor xia inhibitors

专利号:EP-3070087-A1
优先权日:2011-08-05
标 题 :Intermediates for the synthesis of cyclic p1 linkers as factor xia inhibitors

专利号:ES-2733096-T3
优先权日:2011-08-05
标题:Intermediaries for the synthesis of cyclic P1 linkers as XIA factor inhibitors