CAS: 17406-45-0; (2S,3R,4S,5S,6R)-2-(((2S,3R,4S,5R,6R)-2-(((2R,3R,4R,5R,6R)-4,5-Dihydroxy-2-(Hydroxymethyl)-6-(((2As,4S,5'S,6As,6Bs,8As,8Br,9S,10S,11As,12As,12Br)-5',6A,8A,9-Tetramethyloctadecahydrospiro[naphtho[2',1':4,5]Indeno[2,1-B]Furan-10,2'-Piperidin]-4-yl)Oxy)Tetra

专利信息

专利号:US-2025281557-A1
优先权日:2024-03-08
标 题:Methods for cascade amplifications of therapeutic payloads (catp) & compositions for cancer immunotherapies and gene therapy
发明人：LI YINGZHONG; ZHANG LIBIN
权利人:SUNVAX MRNA THERAPEUTICS INC
摘要:The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of oncolytic defective virus compositions and methods of in vivo synthesis thereof. The composition includes a first nucleic acid construct encoding a self-amplifying mRNA (sa-mRNA) encoding at least one gene of interest (GOI) or a plurality of GOIs, a second nucleic acid construct encoding an mRNA encoding at least one virus structural protein, and at least one payload delivery system.

专利号:CN-110526961-B
优先权日:2019-09-09
标题 :Application of transcription factor participating in regulation and control of synthesis of tomato steroid alkaloid

专利号:US-2025281418-A1
优先权日:2021-08-11
标题:Lipid nanoparticle formulations and methods of synthesis thereof
发明人：SMITH MICHAEL H
权利人:MODERNATX INC
摘要:Stabilized formulations of lipids and nucleic acids, including lipid nanoparticle formulations which encapsulate nucleic acids are disclosed herein. Methods of using the formulations are also provided.

专利号:WO-2024230844-A1
优先权日:2023-05-11
标 题:Cationic lipids and preparation method thereof
发明人：MASHIACH ROI
权利人:RIBOX THERAPEUTICS HK LTD
摘要:The present invention provides cationic lipids and lipid nanoparticle formulations comprising these lipids, alone or in combination with other lipids. These lipid nanoparticles may be formulated with nucleic acids to facilitate their intracellular delivery both in vitro and for therapeutic applications. The present invention also provides methods of chemical synthesis of these lipids.

专利号:CN-120051564-A
优先权日:2023-09-18
标题:A plant Q10 synthesis element for improving the synthesis level of plant coenzyme Q10 and its application

专利号:US-12102085-B2
优先权日:2013-10-18
标题 :Insecticidal active mixtures comprising carboxamide compound
发明人：SIKULJAK TATJANA; GEWEHR MARKUS
权利人:BASF AGROCHEMICAL PRODUCTS BV
摘要:The present invention relates to pesticidal mixtures comprising as active compound I an insecticidal active carboxamide derivative and at least one active compound II selected from a group M comprising acteylcholine esterase inhibitors, GABA-gated chloride channel antagonists, sodium channel modulators, nicotinic acteylcholine receptor agonists/antagonists, allosteric nicotinic acetylcholine receptor activators, chloride channel activators, juvenile hormone mimics, homopteran feeding blockers, mit grow inhibitors, inhibitors of mitochondrial ATP synthase, uncouplers of the oxidative phosphorylation, inhibitors of the chitin biosynthesis, moulting disruptors, ecdyson receptor agonists, octamin receptor agonists, inhibitors of the MET, voltage-dependent sodium channel blockers, inhibitors of the lipid synthesis, ryanodine receptor modulators and other compounds as defined in the description, in synergistically effective amounts.The invention relates further to methods and use of these mixtures for combating and controlling insects, arachnids or nematodes in and on plants, and for protecting such plants being infested with pests, especially also for protecting plant proparagation material, such as seeds.