📜Dl-色氨酸置于氯化亚砜体系中,用 甲醇 作为反应溶剂,化学反应生成 Dl-色氨酸甲酯盐酸盐 参考文献:Process For Preparing Optically Active Tryptophans 标题:Process For Preparing Optically Active Tryptophans 摘要:介绍了一种dl-色氨酸的生化光学分辨方法,其中dl-色氨酸酰胺与能够产生酰胺酶的微生物的培养产物或其处理产物相互作用.在混合的dl-色氨酸酰胺中,L-色氨酸酰胺被不对称水解,形成光学活性的l-色氨酸,收率高,几乎所有的d-色氨酸酰胺都没有被水解.在分离l-色氨酸后,剩下的d-色氨酸酰胺很容易被水解,形成光学活性的d-色氨酸,收率高.
专利号:US-2023220381-A1 优先权日:2020-06-30 标 题 :Dna-encoded functionalized aptamers 发明人:SLEIMAN HANADI; LACROIX DE VIMEUR DE ROCHAME DONATIEN PHILIPPE MARIE; MCKEAGUE MAUREEN; HIRKA SERHII; SALIBA DANIEL; ANDERSON SHAUN IAN 权利人:THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING / MCGILL UNIV 摘要:It is provided the synthesis of an aptamer-like encoded oligomer (ALEnOmer), method of producing same and method of preparing a library of ALEnOmes. More particularly, the method of preparing ALEnOmer comprises coupling at least one phosphoramidite monomer with an orthogonal protecting group, and the ALEnOmer produces comprises a DNA coding strand covalently attached to an oligomer through a branching unit, wherein the oligomer has a degree of polymerization at least 5 and is an aptamer.
专利号:US-4267344-A 优先权日:1972-09-22 标 题:N-Substituted N-carboxyanhydrides of α-amino acids and their application in the preparation of peptides 发明人:HALSTROM JOHN B; KOVACS KAROLY G 权利人:PROTEINKEMISK INST TILKNYTTET 摘要:N-Substituted N-carboxyanhydrides of α-amino acids, useful in peptide syntheses, and peptide synthesis process using such compounds, are disclosed. The N-substituent is penta(lower alkoxy)benzyl, or optionally substituted 9-xanthyl, 9-thioxanthyl or 9-selenoxanthyl.
专利号:EP-4540239-A1 优先权日:2022-08-31 标题 :Chiral synthesis of nornicotine and nicotine