CAS: 54-36-4; 2-Methyl-1,2-Di(Pyridin-3-yl)Propan-1-One

相似化合物

51227-29-3 14578-20-2 6339-93-1

上下游产品

CAS号15825-89-5 Pyridine, 3-(1-... | CAS号6304-18-3 3-propan-2-ylpy... | CAS号15031-77-3 2-(吡啶-3-基)丙-2-醇 | CAS号17159-42-1 metyrapol

📜3-乙酰基吡啶置于硫酸,溶剂黄146,异丙醇体系中,化学反应生成 甲吡酮
参考文献:Amphenone Analogs. Iii. Pinacol-Pinacolone Type Rearrangement In The Pyridine Series1
标题:Amphenone Analogs. Iii. Pinacol-Pinacolone Type Rearrangement In The Pyridine Series1
摘要:
DOI:10.1021/ja01524A050

专利信息

专利号:US-8802660-B2
优先权日:2007-03-12
标 题:De novo synthesis of glucocorticoids in the epidermis and its uses and applications
发明人：TOMIC-CANIC MARJANA; BREM HAROLD; SAMUELS HERBERT H
权利人:TOMIC-CANIC MARJANA; BREM HAROLD; SAMUELS HERBERT H; UNIV NEW YORK
摘要:The present invention relates to methods and compositions that control, i.e., antagonize/inhibit or agonize/stimulate, de novo glucocorticoid production in the skin. Such methods and compositions can be used for the prevention and/or treatment of a variety of skin conditions, including inflammation, acute wounds, chronic non-healing wounds, keloid, fibrotic or hypertrophic scars, and epithelial-derived cancer.

专利号:US-10053426-B2
优先权日:2014-12-23
标 题 :Process for the synthesis of metyrapone and alkylated metyrapone analogs
发明人：WILLIAMS ERIC L; SUNDERHAUS JAMES D; SPRINGER JAMES J
权利人:ALBEMARLE CORP
摘要:Process for preparing metyrapone type compounds are generally described herein. In particular, one step process for preparing metyrapone type compounds are described herein. Such processes generally include an alpha-carbon arylation coupling reaction between 3-isobutyrylpyridine and 3-halopyridine compounds in the presence of a palladium catalyst and a phosphine ligand to form the metyrapone-type compounds.

专利号:EP-1886695-A1
优先权日:2006-06-27
标 题:Pharmaceutical combination of an aldosterone synthase inhibitor and a glucocorticoid receptor antagonist or a cortisol synthesis inhibitor or a corticotropin releasing factor antagonist
发明人：SCHUMACHER CHRISTOPH
权利人:SPEEDEL EXPERIMENTA AG
摘要:The invention relates to a pharmaceutical combination comprising (a) an aldosterone synthase inhibitor or a pharmaceutically acceptable salt thereof, and (b) a glucocorticoid receptor antagonist or a cortisol synthesis inhibitor or a cortisol re-synthesis inhibitor or a corticotrophin-releasing hormone receptor antagonist or combinations thereof or in each case a pharmaceutically acceptable salt thereof. Said composition is useful for the manufacture of a medicament, in particular for the manufacture of a medicament for the prevention of, delay of progression of treatment of a disease or condition characterized by the metabolic syndrome.

专利号:US-2021275545-A1
优先权日:2018-11-21
标 题 :Method of treating cancer preferably characterized by expression of a fusion protein comprising a member of the e-twenty-six family by administering an agent that inhibits the synthesis and/or activity of cortisol
发明人：YARDEN YOSEF; SRIVASTAVA SWATI
权利人:YEDA RES & DEV
摘要:A method of treating a cancer selected from the group consisting of a myeloid malignancy, a lymphoid malignancy and Ewing's sarcoma is disclosed. The method comprises administering to the subject a therapeutically effective amount of an agent that inhibits the synthesis and/or activity of cortisol.

专利号:US-8071785-B2
优先权日:2006-06-09
标题:Synthesis and evaluation of 18F-labelled-alkyl-1-[(1R)-1-phenylethyl]-1H-imidazole-5-carboxylate as a tracer for the quantification of β-11-hydroxylase enzyme in the adrenal glands
发明人：LANGSTROM BENGT; KARIMI FARHAD; BLOM ELISABETH; ERLANDSSON MARIA
权利人:LANGSTROM BENGT; KARIMI FARHAD; BLOM ELISABETH; ERLANDSSON MARIA; GE HEALTHCARE LTD
摘要:Radioactively labeled derivatives of (R)-3-(1-phenylethyl)-3H-imidazole-4-carboxylic acid esters and one-step methods for preparing these compounds are provided. The radioactively labelled compounds, and pharmaceutical acceptable salts and solvates are useful as radiopharmaceuticals, especially for use in Positron Emission Tomography (PET) for the diagnosis of adrenal cortical masses such as incidentaloma, adenoma, primary and metastatic cortical carcinoma. Associated kits and method for PET studies are also provided.

专利号:CN-115121281-A
优先权日:2022-07-14
标题 :Preparation of a metal iron-doped FAU-type zeolite and its application in the synthesis of 701 polymerization inhibitor