专利号:US-3978084-A 优先权日:1973-12-03 标题 :Synthesis of biotin 发明人:CONFALONE PASQUALE NICHOLAS; USKOKOVIC MILAN RADOJE; PIZZOLATO GIACOMO 权利人:HOFFMANN LA ROCHE 摘要:Synthesis of biotin from 4-carbomethoxy-2-(4,5-dihydrothiophen-3(2H)-one)-valeric acid methyl ester, and thiophene intermediates in this synthesis.
专利号:US-4029647-A 优先权日:1973-12-03 标 题 :Synthesis of biotin 发明人:CONFALONE PASQUALE NICHOLAS; USKOKOVIC MILAN RADOJE; PIZZOLATO GIACOMO 权利人:HOFFMANN LA ROCHE 摘要:Synthesis of biotin from 4-carbomethoxy-2-(4,5-dihydrothiophen-3(2H)-one)-valeric acid methyl ester, and thiophene intermediates in this synthesis.
专利号:US-2004053999-A1 优先权日:1997-09-17 标题 :Novel compounds and methods for synthesis and therapy 发明人:BISCHOFBERGER NORBERT W; DAHL TERRENCE C; HITCHCOCK MICHAEL J M; KIM CHOUNG U; LEW WILLARD; LIU HONGTAO; MILLS ROGER G; WILLIAMS MATTHEW A 摘要:Novel compounds are described. The compounds generally comprise an acidic group, a basic group, a substituted amino or N-acyl and a group having an optionally hydroxylated alkane moiety. Pharmaceutical compositions comprising the inhibitors of the invention are also described. Methods of inhibiting neuraminidase in samples suspected of containing neuraminidase are also described. Antigenic materials, polymers, antibodies, conjugates of the compounds of the invention with labels, and assay methods for detecting neuraminidase activity are also described.
专利号:US-6225341-B1 优先权日:1995-02-27 标 题:Compounds and methods for synthesis and therapy 发明人:BISCHOFBERGER NORBERT W; KIM CHOUNG U; LEW WILLARD; LIU HONGTAO; WILLIAMS MATTHEW A 权利人:GILEAD SCIENCES INC 摘要:Novel compounds are described. The compounds generally comprise an acidic group, a basic group, a substituted amino or N-acyl and a group having an optionally hydroxylated alkane moiety. Pharmaceutical compositions comprising the inhibitors of the invention are also described. Methods of inhibiting neuraminidase in samples suspected of containing neuraminidase are also described. Antigenic materials, polymers, antibodies, conjugates of the compounds of the invention with labels, and assay methods for detecting neuraminidase activity are also described.
专利号:CN-1153764-A 优先权日:1996-01-02 标题:A new method for the synthesis of borneol by esterification and saponification of pinene and a boron-titanium based composite catalyst
专利号:DE-69812395-T2 优先权日:1997-08-21 标 题:METHOD FOR THE SYNTHESIS OF TAXANS
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