专利号:US-2024309024-A1 优先权日:2023-03-14 标题 :Direct synthesis of alkenylhalosilanes 发明人:LEWIS KENRICK MARTIN; ZHU YANJUN; BYRNE CHRISTOPHER M 权利人:MOMENTIVE PERFORMANCE MAT INC 摘要:A process for the direct synthesis of alkenylhalosilane monomers. Forming a slurry of liquid and copper-activated silicon from fresh silicon, cyclone fines and/or fine dust from silicon grinding, ultrafines and/or spent contact mass from the Direct Synthesis of alkylhalosilanes and arylhalosilanes, in a thermally stable solvent. Reacting the silanes by agitating the slurry with at least one unsaturated aliphatic or cycloaliphatic organohalide of the formula R1X, and optionally an organohalosilane and/or hydrogen halide, in the presence of a polymerization inhibiting Lewis base additive, at a reaction time, temperature and pressure effective to produce alkenylhalosilanes having the formulae, R1SiHX2, R12SiHX, R13SiX, R1SiX3, and R12SiX2 or mixtures thereof.
专利号:US-9469614-B2 优先权日:2011-10-27 标 题:Synthesis of triazolopyrimidine compounds 发明人:ZUPANCIC BORUT; MARAS NENAD; STERK DAMJAN 权利人:LEK PHARMACEUTICALS 摘要:The present invention relates to the field of organic synthesis and describes the synthesis of specific triazolopyrimidine compounds and intermediates thereof as well as related derivatives.
专利号:US-7605290-B2 优先权日:2006-07-26 标题 :Processes for the synthesis of O-desmethylvenlafaxine 发明人:NIDDAM-HILDESHEIM VALERIE; SHENKAR NATALIA; SHACHAN-TOV SHARONA 权利人:TEVA PHARMA 摘要:The present invention describes processes for the preparation of O-desmethylvenlafaxine and tridesmethylvenlafaxine, which may be used as an intermediate in preparing O-desmethylvenlafaxine.
专利号:US-2009069601-A1 优先权日:2006-07-26 标题:Processes for the synthesis of O-desmethylvenlafaxine 发明人:NIDDAM-HILDESHEIM VALERIE; NIDAM TAMAR; DOLITZKY BEN-ZION 权利人:NIDDAM-HILDESHEIM VALERIE; NIDAM TAMAR; DOLITZKY BEN-ZION 摘要:The present invention describes processes for the preparation of O-desmethylvenlafaxine and tridesmethylvenlafaxine, which may be used as an intermediate in preparing O-desmethylvenlafaxine.
专利号:US-2008221356-A1 优先权日:2006-07-26 标题:Processes for the synthesis of O-desmethylvenlafaxine 发明人:NIDDAM-HILDESHEIM VALERIE; NIDAM TAMAR; DOLITZKY BEN-ZION 权利人:NIDDAM-HILDESHEIM VALERIE; NIDAM TAMAR; DOLITZKY BEN-ZION 摘要:The present invention describes processes for the preparation of O-desmethylvenlafaxine and tridesmethylvenlafaxine, which may be used as an intermediate in preparing O-desmethylvenlafaxine.
专利号:US-2009137846-A1 优先权日:2006-07-26 标题 :Processes for the synthesis of O-Desmethylvenlafaxine 发明人:NIDDAM-HILDESHEIM VALERIE; NIDAM TAMAR; DOLITZKY BEN-ZION; FRENKEL GUSTAVO 权利人:NIDDAM-HILDESHEIM VALERIE; NIDAM TAMAR; DOLITZKY BEN-ZION; FRENKEL GUSTAVO 摘要:The present invention describes processes for the preparation of O-desmethylvenlafaxine and tridesmethylvenlafaxine, which may be used as an intermediate in preparing O-desmethylvenlafaxine.
摘要:Lattanzi, A., Science of Synthesis: Stereoselective Synthesis, (2011) 3, 995. 摘要:Katsuki, T., Science of Synthesis: Water in Organic Synthesis, (2012) 1, 60.