CAS: 1486-28-8; Methyldiphenylphosphine

该化合物是一种有机磷磷磷光化合物,其特点是将磷原子结为两个苯基组和一个甲基组;该化合物一般视其纯度和温度而定,呈现为无色的黄色液体或固态,因其在化学和催化协调中的作用而闻名,特别是在涉及过渡性金属的反应中的作用.在标准条件下,甲基二苯磷光具有中等稳定性,但对氧化具有敏感性,这可能导致磷氧化物的形成.有机溶剂中的溶解性使其在各种合成应用中有用,包括有机合成和有机金属复合物的制备.此外,由于有机磷化合物的潜在毒性和环境关切,必须谨慎处理该化合物.总体而言,甲基苯磷是化学研究和工业应用中有价值的试剂.

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ECHA物质ECHA物质C&L通报REACH预注册

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CAS号2129-89-7 甲基二苯基氧化膦 | CAS号603-35-0 三苯基膦 | CAS号74-88-4 碘甲烷 | CAS号2181-42-2 三甲基碘代磺酸 | CAS号17154-34-6 二苯基(三甲基硅基)膦 | CAS号75-16-1 甲基溴化镁 | CAS号1079-66-9 氯代二苯基膦 | CAS号57901-20-9 Benzenamine,N-(... | CAS号98288-14-3 (E)-3-(2-氯苯基)丙烯酸甲酯 | CAS号110296-02-1 methyl 3-(2-chl... | CAS号106141-00-8 methyl-diphenyl... | CAS号21955-55-5 benzyl-methyl-d... | CAS号19713-73-6 Methyl (2Z)-3-p... | CAS号103-26-4 肉桂酸甲酯 | CAS号603-32-7 三苯基胂 | CAS号2129-89-7 甲基二苯基氧化膦 | CAS号937-53-1 (Z)-4-Phenyl-3-... | CAS号1896-62-4 反式苯亚甲基丙酮

合成工艺路线路线简述

    📜四苯基二膦置于sodium体系中,用 四氢呋喃,二丁醚 用作溶剂,化学反应 7.25H,反应生成二苯基甲氧基膦
    参考文献:Diemert,Klaus; Hahn,Thomas; Kuchen,Wilhelm,Phosphorus,Sulfur And Silicon And The Related Elements,1991,Vol. 60,# 3/4,P. 287-294
    标题:Diemert,Klaus; Hahn,Thomas; Kuchen,Wilhelm,Phosphorus,Sulfur And Silicon And The Related Elements,1991,Vol. 60,# 3/4,P. 287-294

    海关参考信息

    专利信息


    专利号:US-9266915-B2
    优先权日:2012-09-24
    标题 :Synthesis of open metal carbonyl clusters
    发明人:KATZ ALEXANDER S; KUPERMAN ALEXANDER; OKRUT ALEXANDER; RUNNEBAUM RON C; OUYANG XIAOYING
    权利人:CHEVRON USA INC; UNIV CALIFORNIA
    摘要:The present invention is directed to the synthesis of novel stable open metal clusters by selective oxidation of bound ligands. The synthesis comprises, for example, using an amine based oxidant for decarbonylation of specific carbonyl ligands. The synthesis can also comprise further removal of a bound amine group by an acid. The resulting metal cluster contains a coordinatively unsaturated site comprising a carbonyl vacancy. The resulting metal cluster can be used as a catalyst in a variety of chemical transformations.

    专利号:US-4749806-A
    优先权日:1984-12-28
    标题:Process for the synthesis of isocyanates and of isocyanate derivatives
    发明人:TKATCHENKO IGOR; JAOUHARI RABIH; BONNET MICHEL; DAWKINS GORDON; LECOLIER SERGE
    权利人:POUDRES & EXPLOSIFS STE NALE
    摘要:The present invention relates to a process for the synthesis of isocyanates and of isocyanate derivatives. Isocyanates are obtained by reacting an organic halide with a metal cyanate in an organic medium in the presence of a catalyst consisting of a complex of nickel with at least one organic ligand, in which complex the nickel is in the zero oxidation state. A carbamate or a urea, respectively, are obtained by a subsequent reaction with a hydroxy compound or a primary or secondary amine. Isocyanates and their derivatives are used especially either as refined synthesis agents for the production of pesticides and medications, or as monomers or comonomers for the preparation of many macromolecular compounds.

    专利号:US-4794199-A
    优先权日:1984-07-05
    标题:Process for synthesis of primary amines from olefins, syngas and ammonia
    发明人:LIN JIANG-JEN; KNIFTON JOHN F
    权利人:TEXACO INC
    摘要:This invention concerns the synthesis of primary amines from olefins, synthesis gas and ammonia via an amination process in the presence of a cobalt catalyst, an ether solvent and a tertiary group VB donor ligand.

    专利号:US-6613910-B2
    优先权日:2001-04-02
    标题 :One-pot synthesis of group 8 transition metal carbene complexes useful as olefin metathesis catalysts
    发明人:GRUBBS ROBERT H; MORGAN JOHN P; BENITEZ DIEGO; LOUIE JANIS
    权利人:CALIFORNIA INST OF TECHN
    摘要:The invention provides a novel method for synthesizing transition metal carbene complexes useful as olefin metathesis catalysts. The method is a convenient one-pot synthesis in which transition metal carbenes are prepared in high yield from readily available starting materials via a dihydrogen complex containing two different anionic ligands, preferably a phosphine and a heteroatom-stabilized carbene. The invention additionally provides a method for synthesizing precursors to carbene ligands useful, inter alia, in the aforementioned one-pot synthesis. The precursors are in the form of trichloromethyl adducts of the formula L 1 -CCl 3 , where L 1 is a heteroatom-stabilized carbene ligand, and are prepared by contacting an unsaturated, ionized analog of L-CCl 3 with a non-nucleophilic base in the presence of chloroform.

    专利号:US-2024024489-A1
    优先权日:2020-11-20
    标 题:Protected disaccharides, their process of preparation and their use in the synthesis of zwitterionic oligosaccharides, and conjugates thereof
    发明人:MULARD LAURENCE; DHARA DEBASHIS; PFISTER HELENE; PAOLETTI JULIE; PHALIPON ARMELLE; GUERREIRO-INVERNO CATHERINE
    权利人:PASTEUR INSTITUT
    摘要:The present invention provides zwitterionic oligosaccharides, in particular fragments of the surface polysaccharides from Shigella sonnei and Shigella sonnei conjugates comprising them. The present invention also provides protected disaccharides, their process of preparation and their use in the synthesis of zwitterionic oligosaccharides, and conjugates thereof, the disaccharide repeating unit of Shigella sonnei being: (I)

    专利号:US-2023286918-A1
    优先权日:2020-07-02
    标 题:Manufacturing process for 3,5-dichloropicolinonitrile for synthesis of vadadustat
    发明人:JURKAUSKAS VALDAS; JUNG YOUNG CHUN; KWON TAESOO; KANNAN ARUNACHALAM; GONDI VIJAYA BHASKER
    权利人:AKEBIA THERAPEUTICS INC
    摘要:Disclosed herein are methods and processes of preparing vadadustat or a pharmaceutically acceptable salts thereof, and intermediates (e.g., a compound of Formula (I), (I-F), (II), or (IV), or a pharmaceutically acceptable salts thereof) useful for the synthesis of vadadustat.

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    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:Eilbracht, P., Science of Synthesis, (2009) 48, 415.
    摘要:Hayashi, M., Science of Synthesis Knowledge Updates, (2013) 2, 174.
    摘要:Ayad, T.; Pirat, J.-L.; Virieux, D., Science of Synthesis Knowledge Updates, (2022) 1, 354.
    摘要:Petit, C.; Montchamp, J.-L., Science of Synthesis: Cross Coupling and Heck-Type Reactions, (2012) 2, 343.
    摘要:Chen, P.; Liu, G., Science of Synthesis: Knowledge Updates, (2023) 1, 442.
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