CAS: 136849-88-2; (2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-((((2R,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-2-yl)Oxy)Methyl)Tetrahydro-2H-Pyran-2-Yl (4As,6As,6Br,8Ar,9R,10S,12Ar,12Br,14Bs)-10-(((2S,3R,4S,5S)-3-(((2S,3R,4R,5S,6S)-4-(((2S,3R,4R,5S,6R)-3,4-Dihydroxy-6-(Hydroxymethyl)-5-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-2-yl)Oxy)Tetrahydro-2H-Pyran-2-yl)Oxy)-3,5-Dihydroxy-6-Methyltetrahydro-2H-Pyran-2-yl)Oxy)-4,5-Dihydroxytetrahydro-2H-Pyran-2-yl)Oxy)-9-(Hydroxymethyl)-2,2,6A,6B,9,12A-Hexamethyl-1,3,4,5,6,6A,6B,7,8,8A,9,10,11,12,12A,12B,13,14B-Octadecahydropicene-4A(2H)-Carboxylate

该化合物是一种天然产品,主要来自某些海洋生物,特别是海绵,被归类为二级代谢物,主要来自某些海洋生物,属于已知的化合物类别,以其复杂的结构和潜在的生物活动为名,其特征为独特的分子框架,包括多个环和功能组,有助于其化学反应和生物特性.Macranthoidin B已经研究其潜在的药理效应,包括防炎和细胞毒性活动,使其对医药化学和药物开发感兴趣.它与生物目标的具体互动仍在调查之中,但其结构复杂性表明有可能产生多种生物功能.与许多自然产品一样,提取和净化过程可能具有挑战性,其稳定性在各种条件下是研究和应用的重要考虑因素.

英文名称(2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-((((2R,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-2-yl)Oxy)Methyl)Tetrahydro-2H-Pyran-2-Yl (4As,6As,6Br,8Ar,9R,10S,12Ar,12Br,14Bs)-10-(((2S,3R,4S,5S)-3-(((2S,3R,4R,5S,6S)-4-(((2S,3R,4R,5S,6R)-3,4-Dihydroxy-6-(Hydroxymethyl)-5-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-2-yl)Oxy)Tetrahydro-2H-Pyran-2-yl)Oxy)-3,5-Dihydroxy-6-Methyltetrahydro-2H-Pyran-2-yl)Oxy)-4,5-Dihydroxytetrahydro-2H-Pyran-2-yl)Oxy)-9-(Hydroxymethyl)-2,2,6A,6B,9,12A-Hexamethyl-1,3,4,5,6,6A,6B,7,8,8A,9,10,11,12,12A,12B,13,14B-Octadecahydropicene-4A(2H)-Carboxylate
中文名称灰毡毛忍冬皂苷乙
IUPAC名称(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl (4aS,6aS,6bR,8aR,9R,10S,12aR,12bR,14bS)-10-(((2S,3R,4S,5S)-3-(((2S,3R,4R,5S,6S)-4-(((2S,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-3,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-4,5-dihydroxytetrahydro-2H-pyran-2-yl)oxy)-9-(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-1,3,4,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-octadecahydropicene-4a(2H)-carboxylate
CAS编号136849-88-2
MFCD编号:MFCD20487834
FDA UNII编号:9S74S1AGHC
分子式:C65H106O32分子量:1399.53
产品CID: 573442
产品分类生物化工 → 提取物

相似结构搜索
InChIKey: RKINZCVTEPSBCI-ZBXZRPIVSA-N
InChI=1S/C65H106O32/c1-25-36(71)51(95-55-48(83)44(79)50(31(21-68)91-55)94-54-46(81)42(77)39(74)30(20-67)90-54)49(84)57(88-25)96-52-37(72)28(70)22-86-58(52)93-35-11-12-61(
计算化学: 氢键受体数32.0氢键供体数19.0可旋转键数18.0

物理性质

密度1.6±0.1 g/cm3
pKa:12.50±0.70(预测)
PSA:512.2
LogP:2.27
折射率1.654
溶解性DMF: 30 mg/mL; DMSO: 30 mg/mL; Pbs (Ph 7.2): 5 mg/mL
外观形态白色至浅棕色结晶性固体
储存条件2-8°C，密封保存，干燥环境
产品应用该化合物用于治疗炎症.

上下游产品

灰毡毛忍冬皂苷甲 Macranthoidin A 140360-29-8

合成工艺路线路线简述

📜灰毡毛忍冬皂苷甲,Udp Glucose置于di-O-Glycosyltransferase体系中,化学反应生成灰毡毛忍冬皂苷乙
参考文献:Maldi 成像辅助发现桔梗根中的二氧糖基转移酶
标题:Maldi 成像辅助发现桔梗根中的二氧糖基转移酶
摘要:开发了 Maldi Ms 成像辅助基因组筛选策略,能够鉴定和表征来自桔梗根的二-O-糖基转移酶 Pggt1 .
Doi:10.1002/anie.202301309

海关参考信息

2901210000-乙烯
2901220000-丙烯
2905122000-异丙醇
2905310000-1,2-乙二醇
💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
详情请参考：📖 海关编码查询和海关进出口税则

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供应商参考报价(招募中)

品牌试剂参考报价(招募中)

实用工具

📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

合成参考文献

参考文献:10.1159/000489147
摘要:Fan X, Rao J, Zhang Z, Li D, Cui W, Zhang J, Wang H, Tou F, Zheng Z, Shen Q. Macranthoidin B Modulates Key Metabolic Pathways to Enhance ROS Generation and Induce Cytotoxicity and Apoptosis in Colorectal Cancer. Cell Physiol Biochem. 2018;46(4):1317–30. doi: 10.1159/000489147.
摘要:Huang RS, Lu ZL, Qin DJ, Liao YK, Liang ZN. [Research on quality standards of zhuang medicine Lonicerae dasystylae flos]. Zhongguo Zhong Yao Za Zhi. 2013 Mar;38(5):762–7.