专利号:US-2019154696-A1 优先权日:2015-08-31 标 题 :Colorimetric Labeling and Detection Methods and Compositions 发明人:CLARKE SCOTT; GEE KYLE; FINNESSY CARMEN 权利人:LIFE TECHNOLOGIES CORP 摘要:The present disclosure provides methods, compositions and kits for measuring cellular nascent nucleic acid synthesis by colorimetric labeling of nucleic acid. The nucleic acid synthesis can be measured as cell proliferation, DNA or RNA synthesis, gene expression or apoptosis. Additionally, these methods may be used to screen compounds for their effect on cellular proliferation by treating cells or an organism with the test compound simultaneous to or before treatment with a competitive nucleoside analog.