CAS: 565-74-2; 2-Bromo-3-Methylbutyricacid

相似化合物

76792-22-8 609-12-1 885478-42-2

上下游产品

3-methylbutyric acid 2-bromo-3-methyl-butyraldehyde dibromoacetonitrile isobutyraldehyde ethyl 2-bromoisovalerate 2-methoxy-3-methylbutanoic acid 3-Methylbutenoic acid 2-hydroxy-3-methylbutanoic acid

1-Ethoxy-1-Chloro-3-Methyl-Butane置于chromium(Iii) Oxide,硫酸,水,溴体系中,化学反应生成 2-溴代异戊酸
参考文献:Madinaveitia; Puyal,Anales De La Real Sociedad Espanola De Fisica Y Quimica,1918,Vol. 16,P. 336
标题:Madinaveitia; Puyal,Anales De La Real Sociedad Espanola De Fisica Y Quimica,1918,Vol. 16,P. 336

专利信息

专利号:US-5877278-A
优先权日:1992-09-24
标题:Synthesis of N-substituted oligomers
发明人：ZUCKERMANN RONALD N; GOFF DANE A; NG SIMON; SPEAR KERRY; SCOTT BARBARA O; SIGMUND AARON C; GOLDSMITH RICHARD A; MARLOWE CHARLES K; PEI YAZHONG; RICHTER LUTZ; SIMON REYNA
权利人:CHIRON CORP
摘要:A solid-phase method for the synthesis of N-substituted oligomers, such as poly (N-substituted glycines) (referred to herein as poly NSGs) is used to obtain oligomers, such as poly NSGs of potential therapeutic interest which poly NSGs can have a wide variety of side-chain substituents. Each N-substituted glycine monomer is assembled from two 'sub-monomers' directly on the solid support. Each cycle of monomer addition consists of two steps: (1) acylation of a secondary amine bound to the support with an acylating agent comprising a leaving group capable of nucleophilic displacement by -NH2, such as a haloacetic acid, and (2) introduction of the side-chain by nucleophilic displacement of the leaving group, such as halogen (as a solid support-bound alpha -haloacetamide) with a sufficient amount of a second sub-monomer comprising an -NH2 group, such as a primary amine, alkoxyamine, semicarbazide, acyl hydrazide, carbazate or the like. Repetition of the two step cycle of acylation and displacement gives the desired oligomers. The efficient synthesis of a wide variety of oligomeric NSGs using automated synthesis technology of the present method makes these oligomers attractive candidates for the generation and rapid screening of diverse peptidomimetic libraries. The oligomers of the invention, such as N-substituted glycines (i.e. poly NSGs) disclosed here provide a new class of peptide-like compounds not found in nature, but which are synthetically accessible and have been shown to possess significant biological activity and proteolytic stability. Combinatorial libraries of cyclic compounds are disclosed wherein the cyclic compounds are comprised of at least one ring structure derived from cyclization of a peptoid backbone. The diversity of product compounds is generated by the sequential addition of substituted submonomers. The combinatorial library includes 10 or more, preferably 100 or more, and more preferably 1,000 or more distinct and different compounds. The library includes each of the product compounds in retrievable and analyzable amounts and preferably includes at least one biologically active compound. Methods of synthesizing the combinatorial libraries and assay devices produced using the libraries are disclosed as is methodology for screening for and obtaining biologically active cyclic organic compounds.

专利号:US-4260633-A
优先权日:1980-04-21
标题:Pesticidal esters of amino acids
发明人：ANDERSON RICHARD J; ADAMS KAREN G; HENRICK CLIVE A
权利人:ZOECON CORP
摘要:Novel diastereomeric esters of amino acids, novel intermediates therefor, synthesis thereof, and the use of said esters for the control of pests.

专利号:US-4269981-A
优先权日:1979-09-24
标 题:Certain pyridylmethyl esters of formamido-lower-alkanoates and derivatives thereof
发明人：HENRICK CLIVE A
权利人:ZOECON CORP
摘要:Pyridyl esters and thiolesters of amino acids, intermediates therefor, synthesis thereof and the use of said esters and thiolesters and compositions for the control of pests.

专利号:US-4447613-A
优先权日:1979-08-24
标 题 :Pyridyl esters and thiolesters of aminoalkanoic acids
发明人：HENRICK CLIVE A
权利人:ZOECON CORP
摘要:Pyridyl esters and thiolesters of amino acids, intermediates therefor, synthesis thereof and the use of said esters and thiolesters and compositions for the control of pests.

专利号:CN-106467470-B
优先权日:2015-08-19
标 题 :Novel chiral metal complexes and their use in synthesis of metal complexes1H NMR Spectroscopy for chirality of charged CompoundsUse of

专利号:EP-0789577-A1
优先权日:1995-06-07
标 题:Synthesis of n-substituted oligomers