CAS: 42398-73-2; 6-Methylisoquinoline

上下游产品

4-methyl-benzaldehyde 2,2-diethoxy-ethanamine 6-methyl-1H-indene 2,4,6-Trimethyl-benzenesulfonate2-amino-6-methyl-isoquinolinium; 2,4,6-Trimethyl-benzenesulfonate2-amino-6-methyl-isoquinolinium; 6-methyl-isoquinolin-1-ol 1-chloro-6-methylisoquinoline 6-methyl-1,2,3,4-tetrahydroisoquinoline

以 二苯醚,均三甲苯 作为反应溶剂,化学反应 12.0H,反应生成 6-甲基异喹啉
参考文献:Girling,Ian R.; Widdowson,David A.,Journal Of The Chemical Society. Perkin Transactions I,1988,P. 1317-1324
标题:Girling,Ian R.; Widdowson,David A.,Journal Of The Chemical Society. Perkin Transactions I,1988,P. 1317-1324

专利信息

专利号:US-3919155-A
优先权日:1970-12-18
标题:Synthesis of aromatic amines by reaction of aromatic compounds with ammonia
发明人：SQUIRE EDWARD NOONAN
权利人:DU PONT
摘要:An improved process for producing an aromatic amine is provided in which an aromatic compound is reacted with ammonia in the presence of a conditioned nickel/nickel oxide cataloreactant at a temperature of from about 150*C. to about 500*C. and at a pressure of from about 10 to about 1000 atmospheres and in the presence of from 1 mole percent to 250 mole percent of water based on the molar amount of the aromatic compound.

专利号:US-7935827-B2
优先权日:2003-12-31
标题 :Optically active, heteroaromatic β-hydroxy esters and processes for their preparation from β-keto esters and processes for the preparation of these β-keto esters
发明人：PLATZEK JOHANNES; ZORN LUDWIG; BUCHMANN BERND; SKUBALLA WERNER; PETROV ORLIN
权利人:BAYER SCHERING PHARMA AG
摘要:The present invention relates to new optically active heteroaromatic β-hydroxy esters useful in the synthesis of epothilone derivatives, to certain compounds used to produce these intermediates, as well as to processes for their production.

专利号:US-3929889-A
优先权日:1971-02-16
标 题 :Synthesis of aromatic amines by reaction of aromatic compounds with ammonia
发明人：SQUIRE EDWARD NOONAN
权利人:DU PONT
摘要:An improved process for producing an aromatic amine is provided in which an aromatic compound is reacted with ammonia in the presence of a conditioned nickel/nickel oxide cataloreactant at a temperature of from about 150*C. to about 500*C. and at a pressure of from about 10 to about 1000 atmospheres.

专利号:US-6140505-A
优先权日:1995-03-10
标 题:Synthesis of benzo fused heterocyclic sulfonyl chlorides

专利号:US-8754237-B2
优先权日:2006-02-14
标题:Bifunctional histone deacetylase inhibitors
发明人：BRADNER JAMES ELLIOT; MAZITSCHEK RALPH; TANG WEIPING; SCHREIBER STUART L
权利人:BRADNER JAMES ELLIOT; MAZITSCHEK RALPH; TANG WEIPING; SCHREIBER STUART L; HARVARD COLLEGE; DANA FARBER CANCER INST INC
摘要:In recognition of the need to develop novel therapeutic agents and efficient methods for the synthesis thereof, the present invention provides novel bifunctional, trifunctional, or multifunctional compounds for inhibiting histone deacetylases, and pharmaceutically acceptable salts and derivatives thereof. The present invention further provides methods for treating disorders regulated by histone deacetylase activity (e.g., proliferative diseases, cancer, inflammatory diseases, protozoal infections, hair loss, etc.) comprising administering a therapeutically effective amount of an inventive compound to a subject in need thereof. The present invention also provides methods for preparing compounds of the invention.

专利号:WO-2018031521-A1
优先权日:2016-08-08
标 题:Aureobasidium derivatives and methods of synthesis