CAS: 2624-43-3; Cyclofenil,4,4'-(Cyclohexylidenemethylene)Bisphenol1,1'-Diacetate

上下游产品

2,2-bis(4-hydroxyphenyl)methylenecyclohexane acetic anhydride 1,1'-(cyclohexylidenemethylene)bis(4-methoxy)benzene 4,4'-Dihydroxybenzophenone2,2-bis(4-hydroxyphenyl)methylenecyclohexane

📜4,4'-二羟基二苯甲酮置于titanium(III) Chloride,Lithium体系中,用 吡啶,乙二醇二甲醚 用作溶剂,化学反应 17.0H,反应生成环芬尼
参考文献:低价钛新合成赛庚啶和相关化合物
标题:低价钛新合成赛庚啶和相关化合物
摘要:描述了一种基于两种合适的酮与低价钛的不对称二羰基偶联制备联苯亚甲基哌啶,赛庚啶和相关化合物的简单方法.
Doi:10.1016/s0040-4020(01)89809-4

专利信息

专利号:US-11873305-B2
优先权日:2020-06-30
标题 :Processes for synthesis of substituted indole intermediates for the synthesis of serd compounds
发明人：ZHANG HAIMING; XU JIE; WUITSCHIK GEORG; ANGELAUD REMY; HEROLD SEBASTIAN; STUTZ ALFRED; BRUETSCH TOBIAS; BURKHARD JOHANNES
权利人:GENENTECH INC; HOFFMANN LA ROCHE
摘要:Provided herein are processes for the preparation of indolyl intermediates using Wenker Synthesis for the total synthesis of SERD compounds useful in the treatment of cancer.

专利号:US-8647823-B2
优先权日:2005-07-22
标 题 :Polynucleotide synthesis on a modified surface
发明人：PARK JOON-WON; HONG BONG-JIN
权利人:PARK JOON-WON; HONG BONG-JIN; POSTECH FOUNDATION; POSCO
摘要:The present invention relates to a method for the synthesis of a polynucleotide on a modified surface of a substrate, wherein the modified surface is obtained by chemically modifying with macromolecules in which a plurality of termini of the branched region are bound to the surface and a terminus of the linear region is functionalized.

专利号:US-9936723-B2
优先权日:2014-02-12
标题 :Process for the synthesis of substituted 1-benzyl-3-(1-(isoxazol-4-ylmethyl)-1h-pyrazol-4-yl)imidazolidine-2,4-diones
发明人：FOTSING JOSEPH R
权利人:SENOMYX INC
摘要:The present invention relates to processes and intermediates for the preparation of compounds of formula (I): n nor a salt or oxide thereof, wherein Alk, M1, M2, R1, R2, R3, R4, R5, R6, R7, and n are as described herein. The present invention also relates to compounds of formula (I) and composition comprising a compound of formula (I). Also disclosed is a method of altering or improving the taste of a composition that includes adding to the composition at least one compound of formula (I), in an amount effective to obtain a modified composition having altered or improved taste relative to an otherwise identical composition lacking said compound.

专利号:US-2025289827-A1
优先权日:2022-12-02
标 题:Morphic forms of a mutant braf degrader and methods of manufacture thereof
发明人：YU ROBERT T; HE MINSHENG; SCHNADERBECK MATTHEW J; KREGER BRIDGET; POLLOCK ROY MACFARLANE; JIANG SIYI; LI MEIQI; CHEN BOLU; LU JIANNAN
权利人:C4 THERAPEUTICS INC
摘要:Advantageous isolated morphic forms of (3R)-3-[6-[2-cyano-3-[[ethyl(methyl)sulfamoyl]amino]-6-fluorophenoxy]-4-oxoquinazolin-3-yl]-8-[2-[1-[3-(2,4-dioxo-1,3-diazinan-1-yl)-5-fluoro-1-methylindazol-6-yl]-4-hydroxypiperidin-4-yl]acetyl]-1-oxa-8-azaspiro[4.5]decane (Compound 1), which is a mutant BRAF degrader, and methods to prepare Compound 1 morphic forms for therapeutic applications are provided in the invention. The invention also provides improved methods for the synthesis of Compound 1, new pharmaceutical compositions comprising Compound 1, and new uses of Compound 1.

专利号:US-2024174678-A1
优先权日:2020-06-30
标 题 :Processes for synthesis of substituted indole intermediates for the synthesis of serd compounds

专利号:EP-3104712-A1
优先权日:2014-02-12
标题 :Improved process for the synthesis of substituted 1-benzyl-3-(1-(isoxazol-4-ylmethyl)-1h-pyrazol-4-yl)imidazolidine-2,4-diones