CAS: 21742-00-7; 2-(Trifluoromethyl)Benzyl Chloride

上下游产品

CAS号346-06-5 邻三氟甲基苯甲醇 | CAS号433-97-6 邻三氟甲基苯甲酸 | CAS号346-06-5 邻三氟甲基苯甲醇 | CAS号433-97-6 邻三氟甲基苯甲酸 | CAS号3038-47-9 邻三氟甲基苯乙腈

邻三氟甲基苯甲醛置于sodium Tetrahydroborate,氯化亚砜体系中,用 水 用作溶剂,65.0 °C,90.0 Kpa 条件下,反应 1.33H,反应生成2-三氟甲基苄基氯
参考文献:一种2-甲基-5-氨基三氟甲苯的制备方法
标题:一种2-甲基-5-氨基三氟甲苯的制备方法
摘要:本发明提供一种2‑甲基‑5‑氨基三氟甲苯的制备方法,以2‑三氟甲基苯甲醛为原料,经硼氢化钠还原得到2‑三氟甲基苄醇;经氯化亚砜氯化得到2‑三氟甲基氯苄;再经硝化得到2‑氯甲基‑5‑硝基三氟甲苯;最后加氢还原得到目标产物2‑甲基‑5‑氨基三氟甲苯.本方法易于操作,产品收率高,成本低廉,易于工业化.

专利信息

专利号:WO-2008090570-A1
优先权日:2007-01-25
标题 :Novel antimicrobials
发明人：JAIN RAJESH; TREHAN SANJAY; DAS JAGATTARAN; KAUR GURMEET; KANWAR SANDEEP; MAGADI SITARAM KUMAR
权利人:PANACEA BIOTEC LTD; JAIN RAJESH; TREHAN SANJAY; DAS JAGATTARAN; KAUR GURMEET; KANWAR SANDEEP; MAGADI SITARAM KUMAR
摘要:The present invention relates to novel phenyl oxazolidinone compounds of formula (I) or their pharmaceutically acceptable analogs, tautomeric forms, stereoisomers, polymorphs, prodrugs, metabolites, salts or solvates thereof. The invention also relates to the processes for the synthesis of novel compounds of formula (I) or their pharmaceutically acceptable analogs, tautomeric forms, stereoisomers, polymorphs, prodrugs, metabolites, salts or solvates thereof. The present invention also provides pharmaceutical compositions comprising novel compounds of formula I and methods of using them. The compounds of the present invention are useful as antimicrobial agents, effective against a number of aerobic and/or anaerobic Gram positive and/or Gram negative pathogens such as multi drug resistant Staphylococcus spp., Streptococcus spp., Enterococcus spp., Bacterioides spp., Clostridia spp., H. influenza, Moraxella Spp., as well as acid-fast organisms such as Mycobacterium tuberculosis and the like.

专利号:US-2006211603-A1
优先权日:2004-08-18
标 题:Ramoplanin derivatives possessing antibacterial activity
发明人：RAJU BORE G; CIABATTI ROMEO; MAFFIOLI SONIA I; SINGH UPINDER; ROMANO GABRIELLA; MICHELUCCI ELENA; TISENI PAOLO S; CANDIANI GIANPAOLO; KIM BUM; O'DOWD HARDWIN
权利人:VICURON PHARM INC
摘要:Novel ramoplanin derivatives are disclosed. These ramoplanin derivatives exhibit antibacterial activity. As the compounds of the subject invention exhibit potent activities against gram positive bacteria, they are useful antimicrobial agents. Methods of synthesis and of use of the compounds are also disclosed.

专利号:CN-104829598-A
优先权日:2015-05-27
标题:A kind of quinazolinone compound containing 1,2,4-triazole sulfide and its synthesis method and application