专利号:US-7119212-B2 优先权日:2004-03-30 标 题 :Process for the preparation of tolterodine and intermediates thereof 发明人:COLOMBO LINO; ROSSI ROBERTO; ALLEGRINI PIETRO; CASTALDI GRAZIANO 权利人:DIPHARMA SPA 摘要:A process for the preparation of 6-methyl-4-(R)-phenyl-chroman-2-one and 6-methyl-4-(S)-phenyl-chroman-2-one, intermediates for the synthesis of tolterodine and its (S) enantiomer, by reaction of 6-methyl-coumarin with phenylboronic acids, esters and derivatives thereof, in the presence of chiral catalysts.
专利号:US-2023039836-A1 优先权日:2020-01-10 标 题:Aromatic sulphonamides derivatives that inhibits pdi a3, their synthesis and use 发明人:KALVINS IVARS; CHLOPICKI STEFAN; STOJAK MARTA; ANDRIANOV VICTOR; DOMRACEVA ILONA; KANEPE-LAPSA IVETA; ZELENCOVA DIANA; WIETRZYK JOANNA; TURLEJ ELIZA; STACHOWICZ MARTYNA; JAROSZ JOANNA; MILCZAREK MAGDALENA; KRAMKOWSKI KAROL 权利人:UNIV JAGIELLONSKI 摘要:The invention relates to a new group of aromatic sulphonamides derivatives of formula (I) and their synthesis and use for modulation of the activity of protein disulfide isomerase (PDI). More particularly, the invention provides small molecule inhibitors of PDI A1 that display antiplatelet, antithrombotic and anticancer activities.
专利号:US-2006251786-A1 优先权日:2005-04-19 标 题:Cyclopropanated coumarin derivatives 发明人:TURIN LUCA 权利人:TURIN LUCA 摘要:This invention provides compound or a mixture of compounds of formula (I): n n nwherein R and R 1 are independently a substituted or unsubstituted, straight or branched alkyl or alkoxy group having up to 5 carbons, phenyl or substituted phenyl; R 2 and R 3 are each independently H or CH 3 ; m is an integer from 0 to 4, and n is an integer from 0 to 2. A method for the synthesis of these compounds is also provided, as is their use as aromachemicals and flavorants and compositions, products and articles containing them.
专利号:CA-2640585-A1 优先权日:2003-02-05 标题 :Synthesis of 2-butyl-3-(2'-(1-trityl-1h-tetrazol-5-yl)biphenyl-4-yl)-1,3-diazaspirol{4,4}-non-ene-4-one
专利号:CN-119528828-A 优先权日:2024-11-22 标题 :Synthesis method of methylation product of nitrogen heterocycle or oxygen heterocycle compound
专利号:CN-102532015-A 优先权日:2012-01-18 标 题:Solid phase synthesis method of coumarin and its analogs
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合成参考文献
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