CAS: 7337-45-3; Tert-Butylamine Borane

上下游产品

CAS号16940-66-2 硼氢化钠 | CAS号5041-09-8 异丁胺盐酸盐 | CAS号75-64-9 叔丁胺 | CAS号19287-45-7 乙硼烷 | CAS号150-46-9 硼酸三乙酯 | CAS号75-64-9 叔丁胺 | CAS号1333-74-0 氢 | CAS号75-31-0 异丙胺

Dimethyl Sulfide Borane,叔丁胺 以 二氯甲烷 作为反应溶剂,化学反应 0.5H,反应生成 硼烷-叔丁基胺
参考文献:使用预制的伯胺硼烷有效还原二甲基腙
标题:使用预制的伯胺硼烷有效还原二甲基腙
摘要:摘要 描述了一种使用原位反应生成的胺硼烷络合物还原 N,N-二甲基腙的简便方法.研究发现,伯胺硼烷络合物在还原 N,N-二甲基腙方面表现非常出色,只需 1.1 当量,即可以优异的收率提供相应的空气敏感肼产品.
DOI:10.1080/00397911.2021.2008449

专利信息

专利号:US-4739073-A
优先权日:1983-11-04
标题:Intermediates in the synthesis of indole analogs of mevalonolactone and derivatives thereof
发明人：KATHAWALA FAIZULLA G
权利人:SANDOZ PHARMACEUTICALS CORP
摘要:Compounds of the formula wherein one of R and Ro is and the other is primary or secondary C1-6alkyl not containing an asymmetric carbon atom, C3-6cycloalkyl or phenyl(CH2)m-, wherein R4 is hydrogen, C1-3alkyl, n-butyl, i-butyl, t-butyl, C1-3alkoxy, n-butoxy, i-butoxy, trifluoromethyl, fluoro, chloro, phenoxy or benzyloxy, R5 is hydrogen, C1-3alkyl, C1-3alkoxy, trifluoromethyl, fluoro, chloro, phenoxy or benzyloxy, R5a is hydrogen, C1-2alkyl, C1-2alkoxy, fluoro or chloro, and m is 1, 2 or 3, with the provisos that both R5 and R5a must be hydrogen when R4 is hydrogen, R5a must be hydrogen when R5 is hydrogen, not more than one of R4 and R5 is trifluoromethyl, not more than one of R4 and R5 is phenoxy, and not more than one of R4 and R5 is benzyloxy, R2 is hydrogen, C1-3alkyl, n-butyl, i-butyl, t-butyl, C3-6cycloalkyl, C1-3alkoxy, n-butoxy, i-butoxy, trifluoromethyl, fluoro, chloro, phenoxy or benzyloxy, R3 is hydrogen, C1-3alkyl, C1-3alkoxy, trifluoromethyl, fluoro, chloro, phenoxy or benzyloxy, with the provisos that R3 must be hydrogen when R2 is hydrogen, not more than one of R2 and R3 is trifluoromethyl, not more than one of R2 and R3 is phenoxy, and not more than one of R2 and R3 is benzyloxy, X is -(CH2)n- or -CH=CH-, wherein n is 0, 1, 2 or 3, and Z is wherein R6 is hydrogen or C1-3alkyl, and R7 is hydrogen, C1-3alkyl, n-butyl, i-butyl, t-butyl, benzyl or M, wherein M is a pharmaceutically acceptable cation, the use thereof for inhibiting cholesterol biosynthesis and lowering the blood cholesterol level, and, therefore, in the treatment of hyperlipoproteinemia and atherosclerosis, pharmaceutical compositions comprising such compounds and processes for and intermediates in the synthesis of such compounds.

专利号:US-6875866-B2
优先权日:2002-02-21
标题:Process for synthesis of D1 receptor antagonists
发明人：DAHANUKAR VILAS H; ECKERT JEFFREY M; GALA DINESH; LUCAS BRIAN; SCHUMACHER DORIS P; ZAVIALOV ILIA
权利人:SCHERING CORP
摘要:In one embodiment, the present invention describes the synthesis of a compound of formula n n nand intermediates therefor.

专利号:US-9802934-B2
优先权日:2013-10-17
标 题 :Process for the synthesis of (R)-praziquantel
发明人：QIAN MINGXIN
权利人:TONGLI BIOMEDICAL CO LTD
摘要:The present disclosure relates to a process and new intermediates for the synthesis of (R)-praziquantel, which is obtained through four steps in proper order, that is, condensation reaction, reduction reaction, acylation reaction and ring-closing reaction, using (1R)-2-substituted-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid as starting material. Overall, the present disclosure provides a (R)-praziquantel product with higher optical purity through a process route that is more cost effective and environmentally friendly.

专利号:US-7189849-B2
优先权日:1997-02-10
标 题:Synthesis of acyclic nucleoside derivatives
发明人：LEANNA M ROBERT; RASMUSSEN MICHAEL; HANNICK STEVEN M; TIEN JIEN-HEH J; LUKIN KIRILL A; TIAN ZHENPING; CHANG SOU-JEN; CURTY CYNTHIA B; NARAYANAN BIKSHANDARKOIL A; BELLETTINI JOHN; SHELAT BHADRA; SPITZ TIFFANY
权利人:MEDIVIR AB
摘要:Novel processes towards the synthesis of the antiviral valomaciclovir stearate in which an esterified guanine acetal is reduced to the corresponding alcohol, reacted with an activated amino acid and N-deprotected. The esterified guanine acetal is prepared from a 9-guanine derivative bearing an acyclic hydroxymethylbutylacetal. The processes are amendable to one-pot reactions.

专利号:US-2013133483-A1
优先权日:2010-03-08
标题 :Synthesis of Nanoparticles Using Reducing Gases
发明人：YANG HONG; WU JIANBO; SHI MIAO; GROSS ADAM
权利人:YANG HONG; WU JIANBO; SHI MIAO; GROSS ADAM; UNIV ROCHESTER
摘要:Selective gas-reducing methods for making shape-defined metal-based nanoparticles. By avoiding the use of solid or liquid reducing reagents, the gas reducing reagent can be used to make shape well-defined metal- and metal alloy-based nanoparticles without producing contaminates in solution. Therefore, the post-synthesis process including surface treatment become simple or unnecessary. Weak capping reagents can be used for preventing nanoparticles from aggregation, which makes the further removing the capping reagents easier. The selective gas-reducing technique represents a new concept for shape control of nanoparticles, which is based on the concepts of tuning the reducing rate of the different facets. This technique can be used to produce morphology-controlled nanoparticles from nanometer- to submicron- to micron-sized scale. The Pt-based nanoparticles show improved catalytic properties (e.g., activity and durability).

专利号:US-2006241298-A1
优先权日:2005-04-21
标 题:Methods for synthesis of dicarbamate compounds and intermediates in the formation thereof
发明人：MORTKO HENRY; HE WEIXUAN; ANDERSEN MARC W; DOTSE ANTHONY K; LI JIE
权利人:MORTKO HENRY; HE WEIXUAN; ANDERSEN MARC W; DOTSE ANTHONY K; LI JIE
摘要:Disclosed is a method of making 2-substituted-2-halo-1,3-propanediols via reduction of corresponding malonate compounds. Also disclosed is a method of making 2-substituted-2-halo-1,3-dicarbamate compounds (such as halo derivatives of felbamate, including fluorofelbamate) via reduction of malonate compounds, followed by carbamoylation. Reduction of the malonate compounds is carried out using an electrophilic hydride reagent.