CAS: 6500-81-8; ——
该化合物是一种化学化合物,被归类为循环尿素,主要用于医疗用途,以促生尿液,即增加尿液的产量;是一种乙酸钠盐,其作用机制包括抑制肾脏中Henle环状体厚的长肢中氯化钠共同运输器;这种抑制导致钠,氯化物和水的排泄增加,使其有效地处理与心脏衰竭,肝硬化和肾功能失调有关的水肿等情况;该化合物通常通过静脉或口腔对它进行静脉或口授,其潜在副作用包括电解失衡,脱水和毒性,特别是快速施用或高剂量;同任何药物一样,在治疗过程中,必须认真监测肾功能和电解程度.其化学结构包括苯氧化合物和炭酸,这可导致其化学特性.
- 英文名称——
- 中文名称依他尼酸钠
- IUPAC名称sodium 2-(2,3-dichloro-4-(2-methylenebutanoyl)phenoxy)acetate
- 其它别名Aceticacid, [2,3-dichloro-4-(2-methylene-1-oxobutyl)phenoxy]-, sodium salt (9CI); Acetic acid, [2,3-dichloro-4-(2-methylenebutyryl)phenoxy]-, sodium salt (8CI); Edecrin sodium; Ethacrynate sodium; Ethacrynic acid sodium salt; Lyovac sodiumedecrin; Sodium Edecrin; Sodium[2,3-dichloro-4-(2-methylenebutyryl)phenoxy]acetate; Sodium ethacrynate
- CAS编号6500-81-8
- MFCD编号:MFCD08141842
- FDA UNII编号:K41MYV7MPM
- 分子式:C13H12Cl2NaO4分子量:0.0
- 产品CID: 1632868
- 同类组份化合物CAS6500-81-8 (sodium)58-54-8 (free acid)
- 产品分类有机原料 → 苯类化合物 → 苯和取代衍生物
物理性质
MSDS等安全信息
合成工艺路线路线简述
📜利尿酸 以93的收率获得产物依他尼酸钠
参考文献: A Novel Process For The Preparation Of Ethacrynate Sodium[fr] Nouveau Procédé De Préparation De Sodium D'éthacrynate
标题: A Novel Process For The Preparation Of Ethacrynate Sodium[fr] Nouveau Procédé De Préparation De Sodium D'éthacrynate
摘要:本发明描述了一种新型的乙酰普鲁酸钠制备方法.该方法涉及在有机溶剂存在下,用等摩尔量的烷基羧酸钠盐处理乙酰普鲁酸.该方法得到的产品是基本纯净的形式(纯度大于99%),已知杂质限制在0.1%w/w以下.该方法还涉及乙酰普鲁酸钠的晶体形式及其制备方法.该方法是一种高效且成本效益非常好的商业规模生产基本纯净稳定形式的乙酰普鲁酸钠的方法.
海关参考信息
- 2901210000-乙烯
2901220000-丙烯
2902600000-乙苯
2905310000-1,2-乙二醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-2014315720-A1
优先权日:2012-10-24
标 题 :Polysaccharide ester microspheres and methods and articles relating thereto
发明人：FALLON DENIS G; GARRETT THOMAS S; KIZER LAWTON E; ZAZZARA KAREN L; COMBS MICHAEL T; JOHNSON RICHARD K; DEHART GARY
权利人:CELANESE ACETATE LLC
摘要:A method for producing a polysaccharide ester microsphere may include forming a polysaccharide ester product from a polysaccharide synthesis, wherein the polysaccharide ester product comprises a polysaccharide ester and a solvent; diluting the polysaccharide ester product, thereby yielding a polysaccharide ester dope; and forming a plurality of polysaccharide ester microspheres from the polysaccharide ester dope. Suitable polysaccharides may include, but are not limited to, starch, cellulose, hemicellulose, algenates, chitosan, and any combination thereof. Esters thereof may be organic esters (e.g., acetate and the like), inorganic esters (e.g., sulfonates and the like), or combinations thereof. Further, the solids conent of the polysaccharide ester dope, in some instances, may be greater than about 16 wt %.
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
合成参考文献
参考文献:10.1007/bf00188384
摘要:Ptok M, Carey TE, Altschuler RA. Relationship of monoclonal antibody (KHRI 3 epitope) to cochlear supporting cell microvilli in the guinea pig. European Archives of Oto-Rhino-Laryngology. 1993 Oct;250(6):345–50. doi: 10.1007/bf00188384.
参考文献:10.1007/s11095-006-9080-8
摘要:Shamblin SL, Hancock BC, Pikal MJ. Coupling Between Chemical Reactivity and Structural Relaxation in Pharmaceutical Glasses. Pharmaceutical Research. 2006 Aug 29;23(10):2254–68. doi: 10.1007/s11095-006-9080-8.
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