CAS: 5585-93-3; Oxypendyl
- 英文名称Oxypendyl
- 中文名称奥昔喷地
- IUPAC名称2-(4-(3-(1-Aza-10-phenothiazinyl)propyl)-1-piperazinyl)ethanol
- 其它别名10H-Pyrido[3,2-b][1,4]benzothiazine,1-piperazineethanol deriv.; 10-[3-[1-(2-Hydroxyethyl)-4-piperazinyl]-propyl]thiophenylpyridylamine; 4-[3-(10H-Pyrido[3,2-b][1,4]benzothiazin-10-yl)propyl]-1-piperazineethanol; Oxipendyl; Oxypendyl
- CAS编号5585-93-3
- MFCD编号:MFCD00865541
- FDA UNII编号:Q76F3HAE5V
- 分子式:C20H26N4OS分子量:370.51
- 产品CID: 1530602
- 产品分类有机原料 → 有机氮化合物
物理性质
MSDS等安全信息
上下游产品
CAS号261-96-1 氮杂苯酚噻嗪 | CAS号6631-37-4 2-苯基氨基吡啶 | CAS号42351-33-7 10-(3-piperazin... | CAS号107-07-3 2-氯乙醇合成工艺路线路线简述
📜2-苯胺基吡啶置于碘,Potassium Carbonate,Sulfur,Sodium Amide体系中,用 正丁醇,苯 作为反应溶剂,化学反应生成 奥昔喷地
参考文献:Schuler,W.A.; Klebe,H.,Justus Liebigs Annalen Der Chemie,1962,Vol. 653,P. 172-180
标题:Schuler,W.A.; Klebe,H.,Justus Liebigs Annalen Der Chemie,1962,Vol. 653,P. 172-180
海关参考信息
- 2921211000-乙二胺
2922110001-单乙醇胺
2922192100-二甲氨基乙醇
2922192210-2-二乙氨基乙醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:WO-0054773-A1
优先权日:1999-03-12
标题:Dopamine agonists in combination with nitric oxide donors, compositions and methods of use
发明人：GARVEY DAVID S
权利人:NITROMED INC; GARVEY DAVID S
摘要:The present invention is directed to novel compositions comprising at least one dopamine agonist in combination with at least one nitric oxide donor (i.e. compounds that donate, transfer or release nitric oxide, elevate endogenous levels of endothelium-derived relaxing factor, stimulate endogenous synthesis of nitric oxide or are substrates for nitric oxide synthase). The novel compositions may optionally comprise at least one therapeutic agent, such as, a vasoactive agent, an antimetic agent, and mixtures thereof. The dopamine agonist is preferably apomorphine. The present invention is also directed to methods for treating and/or preventing sexual dysfunctions and/or enhancing sexual responses in patients. In other embodiments, the present invention is directed to methods treating or preventing neurodegenerative diseases, mitochondrial diseases, spinal cord injury, central or psychostimulant addiction, senile dementia, circulatory disorders, cardiovascular disorders, hyperprolactinaemia or myopia. The compounds and/or compositions of the present invention can also be provided in the form of a pharmaceutical kit.
专利号:US-11759496-B2
优先权日:2016-05-10
标题:Compounds and pharmaceutical use thereof in the treatment of cancer
发明人：SUSIN SANTOS A; KAROYAN PHILIPPE; MERLE-BERAL HÉLÈNE
权利人:KAROYAN PHILIPPE
摘要:The present invention relates to a compound or a pharmaceutical salt thereof comprising a hexapeptide sequence of formula (I), its method of synthesis and its use in anticancer therapy. The invention also relates to a pharmaceutical composition for use in the treatment of cancer comprising at least one soluble peptide according to the invention or at least one acid nucleic according to the invention or at least one expression vector according to the invention, or at least one host cell according to the invention and a pharmaceutically acceptable carrier.
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
1: Simpson GM, Angus JW. A preliminary study of oxypendyl in chronic schizophrenia. Curr Ther Res Clin Exp. 1967 Apr;9(4):225-8.
合成参考文献
摘要:Kleemann, A.; Engel, J.; Kutscher, B.; Reichert, D., Pharmaceutical Substances[Online], Thieme: Stuttgart, (2003).
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