CAS: 40290-42-4; 1,2-Dipalmitoyl-Sn-Glycero-3-Phospho-L-Serine, Sodium Salt

上下游产品

1,2-di-O-hexacecanoyl-3-O-benzyl-sn-glycerol 1,2-dipalmitoyl-sn-glycerol 1-hexadecylcarboxylic acid O-benzyl O-[(S)-2-(benzyloxycarbonyl)-2-(benzyloxycarbonylamino)ethyl] O-[1,2-di-(O-palmitoyl)-sn-glycer-3-yl] phosphate 1,2-dipalmitoyl-sn-glycero-3-phosphatidic acid

专利信息

专利号:US-2018312534-A1
优先权日:2015-10-16
标题:Fluorescent anticancer platinum drugs
发明人：SARKAR ARINDAM; MANDAL SWADHIN KUMAR; SENGUPTA ANIRUDDHA; BISWAS GOUTAM; DUTTA PRADIP; SHARMA RUPALI; RAJ JUSTIN PAUL; SURYAVANSHI HEMANT; KUMARI SMITA
权利人:INVICTUS ONCOLOGY PVT LTD
摘要:The present disclosure is in relation to the field of nanotechnology and cancer therapeutics. In particular, the present disclosure relates to fluorescent platinum based compounds. The disclosure further relates to synthesis of said fluorescent platinum based compounds, nanoparticles and compositions comprising said fluorescent platinum based compounds/nanoparticles. The disclosure also relates to methods of managing cancer by the fluorescence changes between aforesaid platinum based compounds and corresponding free ligands, nanoparticles and compositions.

专利号:US-10730899-B2
优先权日:2013-06-14
标 题 :Lipid-based platinum compounds and nanoparticles
发明人：SENGUPTA SHILADITYA; ROY MONIDEEPA; SARKAR ARINDAM; HOSSAIN SK SAMAD; SENGUPTA ANIRUDDHA; DUTTA PRADIP; ANSARI AASIF
权利人:AKAMARA THERAPEUTICS INC
摘要:The present disclosure is in relation to the field of nanotechnology and cancer therapeutics. In particular, the present disclosure relates to platinum based compounds comprising platinum moiety, linker moiety and lipid moiety and corresponding nanoparticles thereof. The disclosure further relates to synthesis of said platinum based compounds, nanoparticles and compositions comprising said platinum based compounds/nanoparticles. The disclosure also relates to methods of managing cancer by employing aforesaid carbene compounds, platinum based compounds, nanoparticles and compositions thereof.

专利号:WO-0109155-A1
优先权日:1999-07-30
标 题 :Cloning of the streptomyces avermitilis genes for glycosylation of avermectin aglycones
发明人：MACNEIL DOUGLAS J; OCCI JAMES; GEWAIN KEITH M
权利人:MERCK & CO INC; MACNEIL DOUGLAS J; OCCI JAMES; GEWAIN KEITH M
摘要:A cluster of genes involved in the synthesis and/or addition of oleandrose to avermectin aglycones has been cloned. A 11-kb PstI clone complemented 28 avermectin glycosylation mutants in seven complementation classes. Sequencing of an 10-kb region identified 9 ORFs and an additional partial ORF. Eight of the ORFs were correlated to the seven glycosylation complementation classes. Sequence comparison to Genbank databases identified 6 genes: dTDP-glucose synthase; dTDP-glucose 4,6 dehydrase; dTDP-4-keto-hexose reductase; dTDP-hexose 3,5 epimerase; dTDP-hexose 3' O-methylase; and an avermectin aglycone-dTDP-oleandrose glycosyltransferase. The ninth ORF was essential for biosynthesis of the avermectin aglycones. The partial ORF encoded part of an avermectin polyketide synthase module 7.

专利号:WO-2024107474-A1
优先权日:2022-11-15
标 题 :Controlled lipid self-assembly for scalable manufacturing of next-generation immune stimulating complexes
发明人：IRVINE DARRELL; HAMMOND PAULA; PIRES IVAN SUSIN
权利人:MASSACHUSETTS INST TECHNOLOGY
摘要:Methods of controlled lipid self-assembly for scalable manufacturing of next-generation immune stimulating complexes (ISCOMs) are described. The methods involve mixing one or more saponins, one or more lipids, one or more sterols, one or more additional adjuvants (e.g., TLR4 agonist), and optionally one or more antigens in the presence of a detergent. Typically, the mixing step is followed by an incubation step, a dilution and/or concentration step, and/or a filtration or dialysis step for removing detergent. Preferably, methods involve a tangential flow filtration (TFF) process suitable for scalable synthesis and Good Manufacturing Practice (GMP) production of highly homogeneous clinical-grade ISCOM-based adjuvants.

专利号:WO-2024223953-A1
优先权日:2023-04-28
标 题:Calixarene compounds, their synthesis and use in pharmaceutical compositions
发明人：VANDER STRAETEN AURÉLIEN; BEVERNAEGIE ROBIN; JABIN IVAN; LAVENDOMME ROY
权利人:QUANTOOM BIOSCIENCES S A; UNIV BRUXELLES
摘要:The invention relates to new compounds of general Formula (I), which can be used in delivery systems for nucleotides. The present invention further relates to pharmaceutical compositions and their use thereof.

专利号:US-11052044-B2
优先权日:2017-03-02
标题 :In situ lipid synthesis for protein reconstitution
发明人：BREA FERNANDEZ ROBERTO JAVIER; COLE CHRISTIAN; DEVARAJ NEAL K; LYDA BRENT; SUNAHARA ROGER
权利人:UNIV CALIFORNIA
摘要:Described herein, inter alia, are compositions and methods useful for the reconstitution of membrane proteins.