CAS: 351-83-7; 4-Fluoroacetanilide

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CAS号158364-41-1 Ethanone, 1-(4-... | CAS号403-42-9 对氟苯乙酮 | CAS号60-35-5 乙酰胺 | CAS号352-34-1 4-氟碘苯 | CAS号460-00-4 对氟溴苯 | CAS号75-36-5 乙酰氯 | CAS号371-40-4 4-氟苯胺 | CAS号108-24-7 乙酸酐 | CAS号103-84-4 N-乙酰苯胺 | CAS号329-79-3 4-氟苯乙酮肟 | CAS号38962-61-7 5-氨基-2-氟苯磺酸 | CAS号330-83-6 4-氟二苯胺 | CAS号364-78-3 4-氟-2-硝基苯胺 | CAS号448-39-5 4'-氟-2'-硝基乙酰苯胺 | CAS号345-17-5 2-氯-5-氟硝基苯 | CAS号583-42-6 5-氟-1H-苯并[d]咪唑-... | CAS号367-31-7 4-氟-1,2-苯二胺 | CAS号459-59-6 4-氟-N-甲基苯胺 | CAS号446-09-3 1-溴-4-氟-2-硝基苯 | CAS号405-67-4 N-乙基-4-氟苯胺

N-乙酰苯胺置于二(叔丁基羰基氧基)碘苯,氟化氢吡啶体系中,用 二氯甲烷 作为反应溶剂,化学反应 12.0H,以68%的收率获得产物4-氟乙酰苯胺
参考文献:Hypervalent Iodine Mediated Para-Selective Fluorination Of Anilides
标题:Hypervalent Iodine Mediated Para-Selective Fluorination Of Anilides
摘要:A Metal-Free Method For The Direct Regioselective Fluorination Of Anilides Has Been Developed. In The Presence Of Bis(Tert-Butylcarbonyloxy)Iodobenzene (Phi(Opiv)(2)) And Hydrogen Fluoride-Pyridine,The Para-Fluorination Products Of Anilides Were Obtained In Moderate To Good Yields. Because Of Its Operational Safety And The Use Of Readily Available Reagents,This New Procedure Provides Facile Access To A Variety Of Para-Fluorinated Anilides.
DOI:10.1021/jo302099D

专利信息

专利号:US-8716485-B2
优先权日:2010-03-29
标 题:Pyrazole synthesis by coupling of carboxylic acid derivatives and enamines
发明人：NEUMANN JULIA; SURI MAMTA; GLORIUS FRANK
权利人:NEUMANN JULIA; SURI MAMTA; GLORIUS FRANK; WESTFÄLISHE WILHELMS UNIVERSITÄT MÃœNSTER
摘要:The invention describes a novel process for synthesizing pyrazoles by means of oxidative conversion of enamines with suitable N-containing carboxylic acid derivatives.

专利号:JP-2013523674-A
优先权日:2010-03-29
标题:Synthesis of pyrazoles by coupling of carboxylic acid derivatives with enamines.

专利号:WO-2017156194-A1
优先权日:2016-03-08
标题:Compositions and methods for inhibiting influenza rna polymerase pa endonuclease
发明人：PUERTA DAVID T; COHEN SETH M; CREDILLE CY V
权利人:UNIV CALIFORNIA; PUERTA DAVID T
摘要:There are provided inter alia metalloenzyme inhibitors, such as inhibitors of influenza A RNA dependent RNA polymerase PA subunit endonuclease, and methods of synthesis and use of the same.

专利号:US-2013012715-A1
优先权日:2010-03-29
标题 :Pyrazole synthesis by coupling of carboxylic acid derivatives and enamines

专利号:DE-102010013282-A1
优先权日:2010-03-29
标题 :Pyrazole synthesis by coupling of carboxylic acid derivatives and enamines

专利号:CN-107880037-A
优先权日:2017-09-27
标题:A kind of synthesis method and application of 2-oxo-2-(arylaniline) ethyl substituted moxifloxacin series compounds